Fourty two cases of peripheral facial paralysis were devided into three groups, and were administered Steroid, CH
3-VB
12, and Steroid plus CH
3-VB
12 respectively. The effect of these drugs on recovery of facial paralysis was determined using the paralysis score method that had been proposed by Yanagihara (1977), and the integrated EMG method that had been proposed by Yagi (1980).
In the case of complete recovery, rated paralysis score and the values of the integrated EMG usually increase linearly. By means of regression analysis, regression line around each value could be determined using the following equation.
Y=B·log X+A (Y=score, B=rate of recovery, X=day, A=constant)
If we assume Y=100%, X shows the number of days taken for complete recovery and constant B, a rate of recovery.
Days taken for complete recovery in Steroid, CH
3-VB
12 and Steroid plus CH
3-VB
12 were 67.3, 54.9 and 40.3, and the rate of recovery 80.7, 92.2 and 112.3 respectively.
Third group, one that was administered Steroid plus CH
3-VB
12, took shorter period of time for complete recovery than the other two groups. It is statistically significant. This means that Steroid and CH
3-VB
12 had a synergistic effect upon recovery of facial paralysis.
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