耳鼻咽喉科臨床
Online ISSN : 1884-4545
Print ISSN : 0032-6313
ISSN-L : 0032-6313
76 巻, 9 号
選択された号の論文の20件中1~20を表示しています
  • 岩橋 寛治
    1983 年 76 巻 9 号 p. 2041-2056
    発行日: 1983/09/01
    公開日: 2011/11/04
    ジャーナル フリー
    The rapid progress of vascular surgery during the past few decades was exceeded the expectations of the most surgeons and investigators.
    New diagnostic techniques such as the Doppler ultrasonic flowmeter, improved vascular substitutes of various types, and new surgical techniques have expanded the field of vascular surgery.
    Endarterectomy, bypass techniques for treating arterial occulusive disease, and surgical resection and replacement of aortic aneurysms have been perfected. Recently, more noninvasive techniques such as percutaneous transluminal angioplasty, have been developed. The availability of the Fogarty embolectomy catheter now makes it possible, under local anesthesia, to extract emboli from all the most common sites, except the renal and other visceral arteries. Dotter first reported percutaneous transluminal angioplasty as a technique for treating atherosclerotic vascular stenoses and occlusions in 1964. Grüntzig described nonsurgical recanalization of superficial femoral artery occlusions and stenoses in the superficial femoral and pelvic arteries with the use of the Grüntzig balloon catheter. Bypass techniques and other forms of organ protection during thoracic aortic and carotid artery cross-clamping provide protection from temporary or permanent dysfunction.
    A variety of disease entities can lead to arterial and venous stenoses, occlusions or dilatation, but here we are concerned exclusively with the problem of arteriosclerosis, Buerger's disease, venous thrombosis and inferior vena cava obstruction with Budd-Chiari syndrome. We treated 7 patients with inferior vena cava obstruction with the Budd-Chiari syndrome. Two patients were treated by a direct surgical approach to the inferior vena cava block, transcardiac membranotomy, and patching with autogenous pericardium after an open resection. Five were treated with a dilator, Fogarty and Grüntzig balloon catheter to fracture the membrane.
  • 松本 康, 中村 光士郎, 藤田 寛, 柳原 尚明
    1983 年 76 巻 9 号 p. 2057-2063
    発行日: 1983/09/01
    公開日: 2011/11/04
    ジャーナル フリー
    A 32-year-old male patient had bilateral facial palsy associated with chronic renal failure and repeated hemodialysis over ten years. He complained of left facial palsy of sudden onset on December 12, 1979. The palsy was diagnosed as Bell's palsy of slight degree. A week later, he noted right facial palsy. Electrodiagnostic examination indicated that the facial nerve had undergone progressive degeneration. However, surgical decompression of the facial nerve was not permitted because of severe anemia and bleeding tendency. The palsies were gradually alleviated and about 75% recovery was attained one year after the onset. About four months later, left palsy increased again. Three months thereafter, an intrameatal mass was found in the left ear and probe examination revealed an epidermoid carcinoma. It was concluded that chronic renal failure, hemodialysis and the intrameatal carcinoma were significantly related to the etiology and affected the clinical course of the facial palsies.
  • 森 弘, 北 真行, 高橋 晴雄, 野中 信二, 中村 一, 由井 正剛
    1983 年 76 巻 9 号 p. 2065-2070
    発行日: 1983/09/01
    公開日: 2011/11/04
    ジャーナル フリー
    The minimal inhibitory concentrations (MIC) of several antibiotics were investigated using staphylococcus aureus, pseudomonas aeruginosa and proteus mirabilis which were obtained by fractional cultivation of specimens from 138 cases of chronic and reccurrent otitis media.
    Thirteen of the 77 colonies (17%) of staphylococcus aureus showed higher MIC's than 25μg/ml and they were observed in children younger than 8 or adults in their thirties.
    When the MIC's for pseudomonas aeruginosa were higher than 6.25μg/ml, the conditions of the patients from whom the specimens were taken proved to be clinically intractable.
    For proteus mirabilis, the MIC's of the cephem antibiotics of the new generation were generally low.
  • 1982年に経験した63耳より
    由井 正剛, 北 真行, 高橋 晴雄, 野中 信二, 中村 一, 森 弘
    1983 年 76 巻 9 号 p. 2071-2076
    発行日: 1983/09/01
    公開日: 2011/11/04
    ジャーナル フリー
    We treated 63 patients with sudden deafness from January to December, 1982.
    The clinical course and results of viral studies in these cases were compared with those of 106 patients with sudden deafness treated from 1976 to 1981.
    1) These 63 patients were 24 male 39 female, aged 11 to 81 years. The highest incidence was in the fifth decade.
    2) Viral studies were positive in 22%, which is lower than in the past 6 years.
    3) Vertigo and viral infection showed in correlation with the prognosis in this study.
    4) Some confusing cases were analyzed separately, since it was difficult to differentiate them from those of sudden deafness: fluctuating hearing loss, Ménière's disease, acute sensorineural hearing loss of low frequencies.
    5) Influenza A virus positive patients had a good prognosis.
  • 第二報 眼振頻度および緩徐相速度からの検討
    大西 正樹, 八木 聡明, 小林 謙, 坂口 文雄, 町井 一史, 稲垣 京子, 横尾 麗子, 神尾 友和
    1983 年 76 巻 9 号 p. 2077-2081
    発行日: 1983/09/01
    公開日: 2011/11/04
    ジャーナル フリー
    Since only a small number clinics are capable of recording ENG on the first visit of patients with vertigo and/or equilibrium disturbance, we studied the relationship between the changes of spontaneous nystagmus in ENG and the number of days from the first visit to the day recording was done. In the first report, we found that there was no relation between the incidence of nystagmus and the number of days until the date of recording within two weeks from the first visit. However, this result represented only the qualitative nature of nystagmus in ENG. In order to clarify this relationship more precisely, quantitative analysis became necessary. In the present study, we analyzed the relationship between the frequency and the slow-phase velocity of nystagmus and the number of days until recording. ENGs were recorded in 1, 260 patients with vertigo and/or disequilibrium and were analyzed. We found a close relationship between the frequency as well as the slow phase of nystagmus and the number of days from the first visit, namely, the frequency and the slow phase of nystagmus significantly decreased with days past. We conclude that the present status of ENG recording in most clinics is insufficient. ENG recording should be carried out as early as possible.
  • 山崎 芳樹, 園部 紀子
    1983 年 76 巻 9 号 p. 2083-2088
    発行日: 1983/09/01
    公開日: 2011/11/04
    ジャーナル フリー
    51才, 女性, 教員. 1980年11月頃より複視, 1981年1月初旬から右眼瞼下垂, 視力低下, 頭痛, 眉毛部の膨隆がみられるようになった. 右前頭部から眼窩内にかけて硬い腫瘤が触れた. 副鼻洞の単純および断層X線写真, CT所見などから前頭洞骨腫と診断す. 脳神経外科と検討したところ, Killian 法では摘出が困難であろうとのことで, 冠状切開法で bifrontal craniotomy を行ない骨腫瘍を摘出した. 硬度は象牙様であった. 大きさは5×3×3cm, 重さは27grであった. 病理組織学的診断も骨腫であった.
  • 森巾 節子, 藤村 英一, 高木 明, 末広 進, 鈴木 庸之, 岩井 一
    1983 年 76 巻 9 号 p. 2089-2097
    発行日: 1983/09/01
    公開日: 2011/11/04
    ジャーナル フリー
    56才女性で, 喉頭限局型アミロイドーシスの一例を経験し, その電顕写真を得たので報告した.
  • 一色 信彦, 大川 正直
    1983 年 76 巻 9 号 p. 2099-2103
    発行日: 1983/09/01
    公開日: 2011/11/04
    ジャーナル フリー
    Vocal efficiency as one of the criteria for evaluating the vocal function has been a subject of investigation in phoniatrics, since van den Berg (1956) calculated it on the basis of measurements of the subglottic pressure, air-flow rate, and SPL of voice.
    Recent advances in instrumentation have made it more practical to measure the subglottic pressure, both DC and AC components of the expiratory air flow and SPL of voice. A variety of indices were proposed to represent or substitute the real vocal efficiency which is the ratio of the acoustic power to the subglottic power. They are the SPL in dB divided by the air flow rate, SPL in dB minus logarithm of the square of the air flow rate or, AC/DC where AC is the effective value of AC component of expiratory air flow and DC is the mean flow rate.
    On the basis of the definition of efficiency (American Standard Terminology), it is emphasized that the efficiency should be the ratio of useful output of the quantity to its total input, and therefore, be without dimension. Technical problems associated with measurement of vocal intensity and AC components of air flow such as the resonant effect of the vocal tract are also discussed.
  • 臼井 信郎
    1983 年 76 巻 9 号 p. 2105-2110
    発行日: 1983/09/01
    公開日: 2011/11/04
    ジャーナル フリー
    We examined the type of reactions shown by the nasal cavity and bronchi when persons with airway hypersensitivity inhaled β-adrenergic stimulants through the nasal cavity and evaluated whether a β-adrenergic stimulant possessed any nasal mucosal volume changing effects.
    The subjects of study, patients with airway hypersensitivity, were divided into two groups.
    Physiological saline solution, 3ml, was administered to the 16 patients of Group 1 and Salbutamol, 3ml, was administered to the 32 patients of Group 2 through the nasal cavity over 3 minutes, using an ultrasonic nebulizer.
    The nasal resistance and oral respiratory resistance were measured, and spirography and the flow-volume curve test were carried out before inhalation and 5 minutes after completion of inhalation.
    No significant differences could be observed in spirography in terms of %FVC or FEV1.0% values before and after inhalation of physiological saline solution, or before and after inhalation of the β-adrenergic stimulant.
    No changes in flow-volume curves could be observed in the physiological saline solution inhalation group, but a significant increase in the V50 values after inhalation could be observed in the β-adrenergic stimulant inhalation group.
    With respect to the nasal conductance, which is the inverse function of the nasal resistance, no significant difference could be observed before and after inhalation in both the physiological saline solution inhalation group and the β-adrenergic stimulant inhalation group.
    The above findings showed that inhalation of the β-adrenergic stimulant through the nasal cavity possessed bronchodilatory actions, and changes in the nasal mucosal volumes could be established.
    Therefore, there is no functional significance in the β-adrenergic receptors in the smooth muscles of the blood vessel wall of the nasal mucous membrane, and even if there is any significance, it is considered to be extremely small.
  • 増山 敬祐, 東家 倫夫, 石川 哮
    1983 年 76 巻 9 号 p. 2111-2119
    発行日: 1983/09/01
    公開日: 2011/11/04
    ジャーナル フリー
    Localized amyloidosis of the airway is a rare condition. The present study describes a case of amyloidosis of the false vocal cord and nasopharynx.
    A 74-year-old male was referred to our outpatient clinic for the purpose of further examination of a mass in the larynx. On examination, the left false vocal cord was found to be swollen and an irregular bulging of the back of the soft palate was also observed.
    Histological examination revealed massive deposits of homogenous, eosinophilic hyaline-like substance in the sub-epithelial connective tissue.
    Under general anesthesia through the tracheotomy opening, laryngofissure was performed on April 2, 1981. After splitting of the thyroid cartilage in the midline, the inner aspect of the larynx was exposed. The lesion occupied the left false vocal cord area but the surface was not ulcerative. The tumorous lesion was removed as much as possible along with the overlying mucosa.
    The resected raw surface was covered by suturing the remaining mucosa.
    Further histological examination showed that the hyaline-like substance was Congored positive and metachromatic. Congo-red stain with polarization was also positive.
    No other part of the body including the rectal mucosa showed signs of amyloid deposits.
  • 高木 範男, 山本 香列, 小林 潔子, 桧垣 清高, 横田 耕二
    1983 年 76 巻 9 号 p. 2121-2125
    発行日: 1983/09/01
    公開日: 2011/11/04
    ジャーナル フリー
    A case of brachial plexus neurinoma was reported with a review of the literature.
    A 31-year-old woman had an enlarging mass of 4 to 5cm in the right supraclavicular area for about six months. Tingling, radiating into the right shoulder and the arm, appeared on moving the mass. The ovoid, elastic hard gray tumor was removed intracapsularly from the sheath of the lower trunk of the right brachial plexus. The tumor was revealed to be a neurinoma of the Antoni A and B mixed type on histological examination. Her postoperative course was benign exept for slight weakness of the grasping power of her right hand which gradually improved in two weeks.
  • 熊井 恵美, 川堀 真一, 海野 徳二
    1983 年 76 巻 9 号 p. 2127-2134
    発行日: 1983/09/01
    公開日: 2011/11/04
    ジャーナル フリー
    Two cases of congenital cystic lesion in the thyroid gland were reported. Case 1, a 74-year-old male, was surgically treated for a cyst which was located in the thyroidal isthmus and surrounded by normal thyroid tissue. The inner surface was covered with a single flat epithelium.
    Case 2, a 6-year-old female, visited us because of a gradually increasing tumor in the right anterior neck. The cyst wall, 2mm in thickness, was lined with columnar ciliated epithelium. Many lymph follicles were observed in the subepithelial layer. The boundary from the normal thyroid tissue was not clear. The content consisted of many lymphocytes. The postoperative course of these two patients were uneventful.
    Embryonal development of the thyroid gland and surrounding tissues are complicated. Congenital cysts in this region originate from the 3rd or 4th pouches, ultimobranchial body or thyroglossal duct.
    We diagnosed these two cases as thyroglossal duct cysts based on the clinical findings and histological examination.
  • Masayoshi Tachibana, Susumu Nakae, Mitsuo Machino, Hiroyuki Morioka, O ...
    1983 年 76 巻 9 号 p. 2135-2139
    発行日: 1983/09/01
    公開日: 2011/11/04
    ジャーナル フリー
    The intercellular junctions of the vascular stria and spiral ligament in the human cochlea were examined by means of the freeze-fracture technique.
    It appeared that the vascular stria and the spiral ligament of the human shared common anatomical characteristics with that of the guinea pig as far as the intercellular junctions are concerned and we could not find any reason not to assume that the electrophysiological nature of the vascular stria of the human is basically identical to that of the guinea pig.
    The tight junctions observed at the apical portion of the marginal cell could be classified as “intermediate to tight”. The junctions observed between the basal cells were classified as “very tight”. Thus the vascular stria is barred from both endolymph and perilymphatic tissue (spiral ligament) by the tight junction.
    Virtually all the component cells of the vascular stria and the spiral ligament seemed to be interconnected by gap junctions. These cells might share a common intracellular ionic environment.
  • その傾向と解析法の検討
    西川 恵子, 関谷 透, 大山 英樹, 奥園 達也, 西川 益利, 日吉 正明
    1983 年 76 巻 9 号 p. 2141-2144
    発行日: 1983/09/01
    公開日: 2011/11/04
    ジャーナル フリー
    前庭神経炎の病因究明の一手段として, 本疾患が感染症であるという仮説に基づき, 血清蛋白分画, 特に, α1-Globulin, α2-Globulin を2元的に考えて, 解析を試みたところ, 前庭神経炎とコントロール群は分離できた. α1-Globulin, α2-Globulin は, ともに感染症急性期に変化する蛋白分画であるところから興味ある知見と考え報告した. さらに症例を増し検討をかさねたい.
  • 山下 敏夫, 二之湯 修
    1983 年 76 巻 9 号 p. 2145-2150
    発行日: 1983/09/01
    公開日: 2011/11/04
    ジャーナル フリー
    Operative specimens of human laryngeal carcinoma were successfully transplanted into athymic nude mice.
    Histological observation of seven transplants showed that the mutation rate increased in early transplants, but was stabilized in the fifth transplant or thereafter.
    Using the 6th transplant, the growth rate was compared between male and female mice and no significant difference was found. This result indicated that there was no sexual participation in laryngeal carcinoma.
  • 湯本 英二
    1983 年 76 巻 9 号 p. 2151-2168
    発行日: 1983/09/01
    公開日: 2011/11/04
    ジャーナル フリー
    As the degree of judged hoarseness increases, the noise component of the spectrogram increases and replaces the harmonic structure. The relationship between these two components has been quantified as harmonics-to-noise (H/N) ratio. The computation is straightforward; 50 consecutive pitch periods of a sustained vowel /a/ are averaged; H is defined to be the energy of the average waveform, while N is the mean energy of the differences between the individual periods and the average waveform.
    The noise the present method measures is not only those components between the harmonic components of the spectrum but also those which overlap the harmonic components. In addition, cycle-to-cycle pitch perturbations (jitter) contribute to the noise component.
    The subjects of this study consisted of 42 normal and 89 pathological cases with varying degrees of hoarseness pre- and post-operatively.
    The H/N ratio of the normal group ranges from 7.0 to 17.0 dB with a mean of 11.9dB. We expect 95% of normal subjects to have a H/N ratio greater than 7.4dB. According to this criterion with a 5 % false alarm rate, 63.2% of the preoperative phonatory samples were differentiated from normals.
    The H/N ratio, the spectrographic classification and jitter showed a significant correlation with the psychophysical measurement of the degree of hoarseness (r=0.809, 0.805 and 0.712, respectively). The result suggested that jitter is less suitable for assessing the degree of hoarseness than the H/N ratio and the spectrographic classification. Since the spectrographic evaluation is subjective and arbitrary, the H/N ratio is the best quantitative index of the degree of hoarseness. The H/N ratio also proved useful for objective assessment of the result of treatment for hoarseness.
  • 兼 典子, 椋代 光夫, 嶽 良博, 垣内 弘, 岩橋 大介, 田端 敏秀
    1983 年 76 巻 9 号 p. 2169-2175
    発行日: 1983/09/01
    公開日: 2011/11/04
    ジャーナル フリー
    未治療時における頭頸部悪性腫瘍患者9例および健常人8例の末梢血リンパ球を用いてIFNのNK活性におよぼす影響を検討した.
    その結果, 250I.U./mlのIFN-α存在下で18時間前処理することにより, 頭頸部悪性腫瘍患者リンパ球に, 健常人と同様, cytotoxicity の増強がみられた.
    これは病期の進行とは関係なく, 大部分の疾患者のリンパ球は, IFN-αに反応し, cytotoxicity が増強された.
    in vitro と同様に in vitro においてもIFNが防御機構を賦活化することが確められねばならないが, 将来は, IFN-γの使用がより効果的であろう.
  • 石川 保之, 中西 和仁
    1983 年 76 巻 9 号 p. 2177-2186
    発行日: 1983/09/01
    公開日: 2011/11/04
    ジャーナル フリー
    The therapeutic effects and safety of Isosorbide were clinically studied in 22 patients with Meniere's disease. Subjective and objective symptoms were checked every two weeks. Isosorbide was effective in 13 of 16 patients (81%) after 6 weeks of ingestion. Of the subjective symptoms, vertigo, nausea and vomiting, headache, and stiff shoulder were significantly alleviated. In contrast, the effects on cochlear symptoms were limited. With regard to objective symptoms, Isosorbide was effective in terms of positionsl nystagmus test but not for the hearing test. Side effects such as dizziness, nausea, and discomfort in the throat, chest and epigastrium were observed in 6 patients (29%).
  • 横山 俊彦, 磯野 節
    1983 年 76 巻 9 号 p. 2187-2195
    発行日: 1983/09/01
    公開日: 2011/11/04
    ジャーナル フリー
    幼小児鼻アレルギーに対するヒスタグロビン (HG) ネビュライザーの効果, 特に投与量, 投与間隔を検討するために, 3才から15才までの本疾患患者47名を対象に, HG1回1/2 vial, 週2回投与群 (A群) と1回1/4 vial, 週3回投与群 (B群) の比較検討を行なった.
    1) 患者の背景に関する各種因子については, 両群の間に有意差は認められなかった.
    2) 各症状および鼻粘膜所見の改善度は, 全般的にみて, A群の方がB群に比べて軽度ながらよかったが, 推計学的には有意の差はみられなかった (P>0.05).
    3) 総合判定は, アレルギー日記, 症状改善の持続性などを考慮に入れ, 鼻粘膜所見の改善度に重点をおいて行なった. その結果, A群では著効8.7%, 有効21.7%, やや有効52.2%, 無効13.0%, 悪化4.3%, B群では著効4.2%, 有効8.3%, やや有効45.8%, 無効41.7%, 悪化0%であった.
    4) 最も改善率の高かったのは, 両群とも鼻症状では鼻閉 (A群30.3%, B群37.5%) 鼻粘膜所見では粘膜色調 (A群41.0%, B群45.5%) であった.
    5) 鼻粘膜所見の下甲介腫脹, 粘膜色調, 鼻汁分泌量の3所見とも, 両群において異常所見の消失例が比較的多く認められた (図5).
    6) 症状改善発現までの期間には, くしゃみ発作, 鼻閉, 鼻汁ともに明らかな傾向はみられず, また両群間にも大差は認められなかった.
    7) 症状改善が観察期間中において持続していた者は, 両群ともに過半数を占めていた.
    8) 副作用は観察期間中一例もなかった.
  • 斎藤 等, 竹中 洋, 貴田 秀樹, 星野 章範, 寺薗 富朗, 西村 秀夫, 水越 治, 只木 信和, 西村 武重, 中村 明正, 竹之内 ...
    1983 年 76 巻 9 号 p. 2197-2208
    発行日: 1983/09/01
    公開日: 2011/11/04
    ジャーナル フリー
    The ciliary movement of the cultured nasal mucosa taken from mice did not show any particular damage after Histaglobin (HG) treatment (1 vial/ml) for 30min.
    The effect of a larger dosage of HG nebulizer was examined for perennial allergic rhinitis. The trial design for patients over 16 years was 4 week treatment with a nebulizer of HG of 1/2 vial over 3 times a week, and half the dose in the younger patients. A multicenter trial of 96 patients revealed 67% efficacy by the total judgment.
    More frequent treatment showed a better improvement. The patients with severe symptoms showed better improvement than those with mild symptoms. Nasal provocation test, histaminopexic action, radioimmunosorbent test and eosinophils in nasal secretion and in blood showed significant betterment after HG nebulizer therapy.
    In summary, it was proved that the nasal mucosa could absorb HG locally and that local application with a nebulizer seemed to show better efficacy than intramusclar injection.
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