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85 巻, 8 号
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隈上 秀伯, 中島 成人1992 年 85 巻 8 号 p. 1183-1194
発行日: 1992/08/01
公開日: 2011/11/04
ジャーナル フリーIt is well known that there is a sex difference in the incidence of many disease. In some disease, the reason for this difference has been elucidated by recent progress in the studies on hormone receptors. Moreover, it is believed that autoimmune disease occur more frequently in women than in men, because the immune response is influenced by the period of hyperactivity or hypoactivity of estrogen. In this paper, Some otorhinolaryngological diseases are discussed from the point of view of sex hormones.抄録全体を表示PDF形式でダウンロード (11924K) -
宮田 英雄, 鈴木 智雄1992 年 85 巻 8 号 p. 1196-1197
発行日: 1992/08/01
公開日: 2011/11/04
ジャーナル フリーPDF形式でダウンロード (1510K) -
―臨床生理学的, 音声学的検査所見について―小島 好雅, 加我 君孝1992 年 85 巻 8 号 p. 1199-1206
発行日: 1992/08/01
公開日: 2011/11/04
ジャーナル フリーIn a 63-year-old man with severe Broca's aphasia, pure tone audiometry and a series of auditory evoked responses demonstrated preservation of primary auditory pathways. Because he did not speak, the standard language test of aphasia was performed for Broca's aphasia. Since it was impossible to continue further tests, we introduced objective methods to evaluate his aphasic disorder. Phonolaryngograms showed that he was unable even to utter vowel sounds. An electronystagmographic study of eye tracking and OKN revealed abnormal eye movements consistent with a functional disorder in the left cerebral hemisphere. Eye movements during reading clearly showed depression of saccadic gaze phases. Although neurophysiological assessment with writing was not done, it was clear that writing was no better than painting.抄録全体を表示PDF形式でダウンロード (3552K) -
―難聴の進行様式と進行速度に関する考察―八木 昌人, 原田 勇彦, 山岨 達也, 菊地 茂1992 年 85 巻 8 号 p. 1207-1213
発行日: 1992/08/01
公開日: 2011/11/04
ジャーナル フリーLong-term observation is necessary to evaluate the clinical course of idiopathic bilateral sensorineural hearing loss (IBSHL). We followed 16 patients with 7 males and 9 females IBSHL for five years or more. The ages at the beginning of observation ranged from 8 to 67 years. None had familial hearing loss.
In nine patients hearing loss progressed in both ears, and in seven hearing loss become worse in only one ear. However, all ears had severe hearing loss. At the beginning of observation various degrees of hearing loss were recorded, but in many cases hearing loss of both ears was severe at the latest observation. Hearing loss of higher tones tended to be more progressive than that of lower tones.
As hearing loss became more profound, the speed of progression decreased. It was considered that the progression of hearing loss might be even slower if the term of observation were longer. Hearing level and length of observation are important in the evaluation of the rate of progress of hearing loss.抄録全体を表示PDF形式でダウンロード (795K) -
―コルメラの固定に対する一工夫―藤野 清大, 伊藤 壽一, 大田 耕造, 徳田 安誠1992 年 85 巻 8 号 p. 1215-1220
発行日: 1992/08/01
公開日: 2011/11/04
ジャーナル フリーFibrin glue was used in 33 patients for ossicular reconstruction: 20 with tympanoplasty type III and 13 with type IV. It was used as an adhesive between the columella and stapes, with gelatin sponge as a supporting material around them.
Fibrin glue makes stabilization of the columella more accurate and firm, and prevents its dislocation. This is particularly advantageous in type IV in which it is difficult to maintain ossicular continuity by any other devices. It has not oxicity for the middle or inner ear. successful results, according to the criteria of the Japan clinical otologic society, were achieved in 54% of type III, and in 44% of type IV tympanoplasties. These results are not as good as those of previously reported tympanoplasties, but this method is useful at least as an operative technique to stabilize the columella easily and surely.抄録全体を表示PDF形式でダウンロード (3277K) -
河北 誠二, 有友 宏, 稲木 匠子, 相原 隆一1992 年 85 巻 8 号 p. 1221-1228
発行日: 1992/08/01
公開日: 2011/11/04
ジャーナル フリーA 49-year-old female consulted our clinic with a complaint of righ trecurrent epistaxis on December 2, 1989. A tumor was found in the right nasal cavity. Radiographic study failed to disclose the extent of the tumor, because of associated paranasal sinusitis. MRI (magnetic resonance imaging) studies suggested that the tumor was limited to the right nasal cavity. Right lateral rhinotomy was performed and the tumor was totally removed on December 27, 1989. The tumor was confirmed to be neurogenic by the findings of intracytoplasmic neurosecretory granules and neuritic processes in the tumor cells examined by electron microscopy. It was diagnosed as olfactory neuroblastoma because of its location and the normal value of urine VMA (vanillyl mandelic acid). There was no evidencel of recurrence during 18 months of follow up. The authors confirmed the usefulness of MRI in the evaluation of the extent of the tumor and the necessity of electron microscopy to diagnose olfactory neuroblastoma.抄録全体を表示PDF形式でダウンロード (5446K) -
―RAST法との比較検討―松原 篤, 朴沢 二郎, 新川 秀一, 池野 敬一, 藤田 猛志, 藤原 美秋1992 年 85 巻 8 号 p. 1229-1234
発行日: 1992/08/01
公開日: 2011/11/04
ジャーナル フリーThe value of the radio allergosorbent test (RAST) in the detection of specific IgE antibody has been investigated by many researches.
However, the clinical usefullness of the CAP-fluoro enzyme immuno assay (CAP-FEIA) method recently introduced for the same purpose as the RAST method is still not clear. The authors used both the RAST and the CAP-FEIA methods to test the same patients with nasal allergy and compared the results.
It was found that the CAP-FEIA method was more sensitive than the RAST method in the detection of specific IgE antibodies to single or multiple antigens in patients with nasal allergy, except for house dust antigens. Further investigation showed that the lower sensitivity to house dust antigen was due to the impurities in the house dust extract.
Reexamination with a new standard house dust extract showed as high sensitivity as to the other antigens. The CAP-FEIA method showed a better correlation with the results of skin tests than did the RAST method.
It is concluded that CAP-FEIA is an excellent method for the diagnosis of nasal allergy.抄録全体を表示PDF形式でダウンロード (526K) -
小川 晃弘, 西岡 慶子, 明海 国賢, 中川 文夫, 内田 哲男1992 年 85 巻 8 号 p. 1235-1243
発行日: 1992/08/01
公開日: 2011/11/04
ジャーナル フリーTwo cases of ethomoidal antrolith in our clinic were reported.
Case 1: A 61-year-old female visited our clinic complaining of right nasal obstruction and rhinorrhea. A calculus in the right anterior ethmoid sinus was removed by surgery. The calculus was milky white, oval shaped, weighed 1.89gr and had no core substance. This was a rather large stone. The main components were calcium phosphate, calcium carbonate and protein.
Case 2: An 18-year-old male visited our clinic complaining of left nasal obstruction and rhinorrhea. A calculus located in the left anterior ethmoid sinus was removed by surgery. The calculus was light brown, oval shaped and weighed 0.18gr and had no core substance. This was a rather small stone. The main components were calcium phosphate, calcium carbonate and protein.
A review of the literature revealed 133 cases of rhinolithiasis in Japan. These are analized statistically.抄録全体を表示PDF形式でダウンロード (4606K) -
―第2報―菊地 茂, 山岨 達也, 洲崎 春海, 青木 彰彦, 原 誠, 野村 恭也1992 年 85 巻 8 号 p. 1245-1252
発行日: 1992/08/01
公開日: 2011/11/04
ジャーナル フリーOne hundred and thirty patients with chronic sinus it is were treated with 400-600mg of erythromycin (EM) per day for adults and 200-300mg per day for children for an average of 5.4 months.
1) Rhinorrhea was improved in 59.8%, postnasal drips in 56.6%, nasal obstruction in 64.0%, olfactory disturbance in 30.6% and head dullness in 85.3%.
2) Rhinoscopy showed decreased nasal discharge in 70.5%, improved quality of nasal discharge in 68.6%, decreased postnasal drip in 78.3% and reduced mucosal swelling in 15.4%.
3) The clinical effect in children was some what inferior to that in adults.
4) The presence of prior sinus surgery and sinobronchial syndrome did not influence the effectiveness of this therapy.
5) No significant side effects were noted during this therapy.
Long-term low-dose erythromycin therapy is considered to be applicable to various types of chronic sinusitis.抄録全体を表示PDF形式でダウンロード (894K) -
池田 敦子, 池田 元久, 渡辺 〓, 小松崎 篤1992 年 85 巻 8 号 p. 1253-1260
発行日: 1992/08/01
公開日: 2011/11/04
ジャーナル フリーCoronal computed tomographic (CT) scanning of the head can image the condition of the paranasal sinuses accurately. The aim of this study is to evaluate conventional sinus X-rays as a screening test in the diagnosis of sinusitis. Conventional sinus X-rays and coronal CT scanning were performed simultaneously in 106 patients in whom sinusitis was diagnosed clinically. After comparing conventional sinus X-rays with coronal CT scanning, the authors calculated the sensitivity and specificity of the diagnosis of sinusitis by conventional sinus X-rays. They found conventional sinus X-rays to be very useful in evaluating maxillary sinusitis, but it was slightly difficult to evaluate accurately the condition of the ethmoid, frontal and sphenoid sinuses. Therefore, in only 13 patients (12.3%) pansinusitis was diagnosed by conventional sinus X-rays, while in 36 patients (34.1%) pansinusitis was diagnosed by coronal CT scanning.抄録全体を表示PDF形式でダウンロード (3434K) -
―1例報告と高齢者に対する手術法―横畠 悦子, 楯 敬蔵, 吉岡 伸高, 岸本 誠司1992 年 85 巻 8 号 p. 1261-1264
発行日: 1992/08/01
公開日: 2011/11/04
ジャーナル フリーA follicular dental cyst was found in an 81-year-old female patient. We report this case because of the low incidence of this condition in aged patients and because its extensionin to the parapharyngeal space is rare. We performed total removal of the tumor by Jaeger's jugal extended incision. We recommend this approach for aged patients because of its excellent wide operative field and good cosmetic results.抄録全体を表示PDF形式でダウンロード (3298K) -
―破裂音構音時の観察―川野 通夫, 田野口 二三子, 木戸 直博, 本庄 巖, 児嶋 久剛, 森 一功1992 年 85 巻 8 号 p. 1265-1268
発行日: 1992/08/01
公開日: 2011/11/04
ジャーナル フリーFaulty articulation of cleft palate speech due to velopharyngeal incompetence can now be defined not only on an auditory basis but more precisely on the basis of the dynamics of the articulatory organs with the use of nasopharyngofiberscopy and videofluoroscopy. In the process of our clinical research, we found 17 patients who had abnormal constriction of the larynx among 42 patients with glottal stop production.
The constriction, related tog lottal stop on plosive consonants resulted from adduction of the arytenoids, medial movement of the aryepiglottic folds, and backward movement of the epiglottal base leading to approximation or even contact between the arytenoids and epiglottal base.
Abnormal laryngeal constriction appears to be closely related to glottal stop.抄録全体を表示PDF形式でダウンロード (1624K) -
磯野 道夫, 山本 悦生, 大村 正樹, 広野 喜信, 水上 千佳司1992 年 85 巻 8 号 p. 1269-1273
発行日: 1992/08/01
公開日: 2011/11/04
ジャーナル フリーSixty three parotid tumors were resected surgically in Kobe City General Hospital from May, 1987, to December, 1989. These cases were classified according to the definitions of the World Health Organization (1972). The most common tumor in our series was pleomorphic adenoma, followed by adenolymphoma (Whartin's tumor; 22%). Compared with past studies, this percentage is much higher than that in previous reports, but the male/female ratio of 6/1 is the same.
The synthetic diagnosis of parotid tumor comprises computed tomography, ultrasound, radioisotope, scintigraphy and magnetic response imaging. The synthetic diagnosis provided adequate differentiation between pleomorphic adenoma and Whartin's tumor but not between malignant and benign tumors.
Ultrasound was thought to be useful as a screening test for finding a tumor in the parotid gland.抄録全体を表示PDF形式でダウンロード (1652K) -
寒川 高男, 田端 敏秀, 斉藤 匡人, 川口 隆明, 與田 順一, 田村 真司1992 年 85 巻 8 号 p. 1275-1280
発行日: 1992/08/01
公開日: 2011/11/04
ジャーナル フリーThe effects of immunochemotherapy combined with regional injection of interleukin-2 (rIL-2) and balloon occluded arterial infusion (BOAI) of cisplatin (CDDP) were evaluated in three patients with tonsillar cancer. Partial response (PR) was obtained in all cases. Immunohistological analysis showed a significant increase of tumor infiltrating lymphocytes (TIL) following immunochemotherapy. A decrease of tumor cell proliferation was detected with the use of Ki-67 monoclonal antibody. Combined immunochemotherapy appears to be useful in the therapy of tonsillar cancer.抄録全体を表示PDF形式でダウンロード (3258K) -
岡部 陽三, 長山 郁生, 三輪 高喜, 宮永 路子, 古川 仭1992 年 85 巻 8 号 p. 1281-1284
発行日: 1992/08/01
公開日: 2011/11/04
ジャーナル フリーA 62-year-old woman visited our hospital complaining of abnormal sensation in the pharynx. Physical examination revealed a pulsating mass on the right side of the posterior wall of the mesopharynx. CT and angiography confirmed that the internal carotid artery had an abnormal course and was compressing the pharyngeal wall.
The clinical importance and etiology of tortuosity of the internal carotid artery are discussed.抄録全体を表示PDF形式でダウンロード (1567K) -
大村 正樹, 山本 悦生, 水上 千佳司, 老木 浩之, 辻 純, 宗田 由紀, 田辺 牧人, 船曳 和雄, 日野 恵, 伊藤 秀臣, 池窪 ...1992 年 85 巻 8 号 p. 1285-1293
発行日: 1992/08/01
公開日: 2011/11/04
ジャーナル フリーSingle photone mission computed tomography (SPECT) with intra-arterial perfusion of 99mTc-macroaggregated albumin (MAA) was used to examine four patients with head and neck cancer. This method was much more accurate in determining the perfusion area of tumors deep in the head and neck than the conventional dye method, Tc-MAA planar method, or arterial angiography. A comparison of Tc+Tc-MAA SPECT with Tc SPECT was the most useful way of identifying the perfusion area. This method also seemed to be useful in the assessment of the effect of intra-arterial perfusion therapy.抄録全体を表示PDF形式でダウンロード (8099K) -
大森 孝一, 山本 悦生, 大村 正樹, 船曵 和雄, 白根 博文, 樋口 佳代子1992 年 85 巻 8 号 p. 1295-1300
発行日: 1992/08/01
公開日: 2011/11/04
ジャーナル フリーWe report a rare case of occult thyroid carcinoma which was found from metastatic parotid tumor. This is the 6th case of thyroid carcinoma presenting as metastatic parotid tumor to be reported in the literature.
A 62-year-old man had complained of left parotid tumor for 4 months. Left total parotidectomy and left neck dissection were performed, and a frozen section of the tumor was diagnosed histopathologically as adenocarcinoma. After the surgery, metastatic papillary carcinoma was found in neck lymph nodes by further pathological examination. Total thyroidectomy was then performed, and the primary tumor, 8mm in diameter, was found in the left lobe of the thyroid. The parotid tumor was diagnosed as metastasis of poorly differentiated thyroid carcinoma by histopathological findings and immunopathological examination using monoclonal antibody (TCM9) specific to the thyroid carcinoma.
It was concluded that the original tumor was the differentiated papillary carcinoma of the thyroid, and that cells of the tumor were transformed to poorly differentiated carcinoma in the neck lymph node and some of those cells metastasized to the parotid gland.抄録全体を表示PDF形式でダウンロード (4693K) -
金地 明星, 野々村 光栄, 福島 英行1992 年 85 巻 8 号 p. 1301-1305
発行日: 1992/08/01
公開日: 2011/11/04
ジャーナル フリーPrimary malignant lymphoma of the thyroid gland has been diagnosed in eight patients in our institute during the past 10 years.
This study examines whether each patient was diagnosed properly preoperatively by means of ultrasonography and fine needle aspiration cytology only.
In four patients Hashimoto's thyroiditis and undifferentiated carcinoma were not differentiated accurately by these two tests.
We conclude that if malignant lymphoma of the thyroid gland is suspected clinically we should resect the thyroid gland for diagnosis and therapy, even if the results of ultrasonography and fine needle aspiration cytology do not show malignancy.抄録全体を表示PDF形式でダウンロード (2805K) -
―文献的考察―中村 隆1992 年 85 巻 8 号 p. 1307-1313
発行日: 1992/08/01
公開日: 2011/11/04
ジャーナル フリーIn 1978 Kemp first provided evidence that acoustic emissions can be detected in the human ear canal after stimulation with clicks. His findings have confirmed by many investigators. Evoked otoacoustic emissions (e-OAE) are cochlear in origin and supported by the existence of an active nonlinear biomechanical mechanism. Recently, evoked otoacoustic emissions have been proposed as a reliable technic for studying cochlear function. The aim of this paper is to review the properties of evoked otoacoustic emissions.抄録全体を表示PDF形式でダウンロード (953K) -
―第2報: 免疫条件下での変化―山脇 利朗, 友田 幸一, 山下 敏夫, 熊澤 忠躬1992 年 85 巻 8 号 p. 1315-1321
発行日: 1992/08/01
公開日: 2011/11/04
ジャーナル フリーWe investigated the effect of inner ear immune responses on the anionicsites of the charge barrier. Guinea pigs were immunized with type II collagen (BIIn), keyhole limpet hemocyanine (KLH) o horse radish peroxidase (HRP) through the stylomastoid foramen to induce a second immune response.
Polyethyleneimine (PEI) was used as a cation tracer. A decrease of the charge in the stria vascularis and endolymphatic sac was found in animals immunized with type II collagen and HRP. The KLH group did not show any of changes because the immune reaction was less due to its high molecular weight and strong negative surface charge.
A decrease of the charge under immunological conditions may induce hyperpermeability of the vessels and disturb endolymph absorption, thus causing endolymphatic hydrops.抄録全体を表示PDF形式でダウンロード (4700K) -
竹田 泰三, 小桜 謙一, 齋藤 春雄, 青山 好希1992 年 85 巻 8 号 p. 1323-1332
発行日: 1992/08/01
公開日: 2011/11/04
ジャーナル フリーMany lines of evidence support the hypothesis that spontaneous otoacoustic emissions (SOAE) are produced by spontaneous mechanical oscillation within the cochlea, and perhaps motile properties of the outer hair cells. If this is the case, SOAE, emitted acoustically in the external auditory meatus, could also be recorded electrically as cochlear AC-potential. In the present study, SOAE were recorded both acoustically and electrically in the guinea pigs to examine the correlation between electrically recorded SOAE (ER-SOAE) and acoustically recorded SOAE (AR-SOAE).
1) In 4 out of 20 guinea pigs (20%), SOAE could be detected both acoustically and electrically.
2) Electrical signals of SOAE had a better S/N ratio than acoustical signals. Generally, only some ER-SOAE could be detected acoustically.
3) Almost without exception, the prominent frequencies (PF) of multiple ER-SOAE correspond to the intermodulation distortion product, or harmonics.
4) ER-SOAE were suppressed by asphyxia or intense sound exposure and reappeared upon re-breathing or discontinuation of the external tone. During recovery PF showed a transient downward shift in frequency.
5) SOAE were synchronized in phase with the external tone in the spectral neighborhood of SOAE. The averaged waveform of SOAE synchronized with the external tone was the same with either acoustic or electrical signals.抄録全体を表示PDF形式でダウンロード (1166K) -
間島 雄一, 坂倉 康夫, 浜口 富美, 村井 須美子1992 年 85 巻 8 号 p. 1333-1340
発行日: 1992/08/01
公開日: 2011/11/04
ジャーナル フリーThis study was desiged to determine the effectiveness of Tsumura Shin'i-seihai-to (TJ-104), a Kampo medicine, in chronic sinusitis. The subjects of this study were 30 patients aged 19 to 80 years, who received TJ-104 7.5g p. o. per day for four weeks.
The general effectiveness of TJ-104 On subjective symptoms and rhinoscopic observations was 69.0%.
Nasal mucociliary clearance (ST) was determined by the saccharin method in 28 subjects before (week 0) and four weeks after the start of the administration (week 4). At week 0, ST was within the normal range in 15 patients, and was retarded in 13 patients. At week 4, ST was signiflcantly better than at week 0 in those patients whose ST was retarded before treatment (p<;0.001). No significant difference was observed in either the elasticity (G') or the viscosity (η') of nasal mucus between week 0 and week 4.
It was concluded that 1) TJ-104 can improve reduced nasal mucociliary clearance, 2) TJ-104 has no effect on reducing the viscoelasticity of the nasal mucus, and 3) TJ-104 is considered to be a useful drug for the conservative treatment of chronic sinusitis.抄録全体を表示PDF形式でダウンロード (3612K) -
―辛夷清肺湯と四逆散の臨床効果―桜田 隆司, 池田 勝久, 高坂 知節, 遠藤 里見, 山田 公彦, 小野寺 亮, 松谷 幸子, 石戸谷 雅1992 年 85 巻 8 号 p. 1341-1346
発行日: 1992/08/01
公開日: 2011/11/04
ジャーナル フリーThe clinical effectiveness of two different Kampo medicines, Tsumura Shin'i-seihai-to (TJ-104) and Shigyakusan (TJ-35) was evaluated in six patients with nonallergic chronic rhinitis and 61 with chronic sinusitis. The clinical effectiveness was graded according to four parameters; subjective symptoms, objective signs, the number of neutrophils in nasal smears, and rhinomanometric resistance. The therapeutic effect of TJ-104 was very good in 2.6%, moderate in 28.9%, slightin 23.7% while that of TJ-35 was very good in 3.7%, moderatein 29.6%, and slight in 25.9%. The differences between these two drugs are not statistically significant. With the improvement of nasal obstruction, the total rhinomanometric resistance decreased significantly in the TJ-104-treated patients (p<0.05). On the other hand, nasal obstruction did not show any correlation with rhinomanometric resistance after TJ-35 treatment.抄録全体を表示PDF形式でダウンロード (768K) -
―心理テストによる型別の検討―鈴木 聡明, 大谷 巌, 安斎 友博, 岡村 洋沖, 三沢 敬典, 服部 政夫, 渡辺 睦, 大槻 好正, 馬場 陽子, 高取 隆, 松村 ...1992 年 85 巻 8 号 p. 1347-1352
発行日: 1992/08/01
公開日: 2011/11/04
ジャーナル フリーThe effect of the minor tranquilizer “Ethyl loaazepate” was correlated with the results of TMI and SRQ-D tests in patients with fbreign body sensation in the throat.
1) “Ethyl loflazepate” reduced subjective symptoms in 90.8% of the patients with fbreign body sensation. 2) “Ethyl loflazepate” was effective not only in patients with neurotic or possibly neurotic scores on TMI and SRQ-D tests but also in those with normal scores. 3) Mild side effects were noted in 9 patients (8.3%) during administration of the drug.
These results suggest that “Ethyl loflazepate” is effective against foreign body sensation in the throat.抄録全体を表示PDF形式でダウンロード (669K) -
本庄 巖1992 年 85 巻 8 号 p. 1354-1355
発行日: 1992/08/01
公開日: 2011/11/04
ジャーナル フリーPDF形式でダウンロード (242K)
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