耳鼻咽喉科臨床
Online ISSN : 1884-4545
Print ISSN : 0032-6313
ISSN-L : 0032-6313
77 巻, 8 号
選択された号の論文の15件中1~15を表示しています
  • 池田 勝久, 桜井 時雄, 小林 俊光, 河本 和友
    1984 年 77 巻 8 号 p. 1565-1572
    発行日: 1984/08/01
    公開日: 2011/11/04
    ジャーナル フリー
    In a study of the middle ear cleft in otitis media with effusion (OME), high-resolution computed tomography was performed in 51 patients aged 3 to 13 years. The patients were divided into the following three groups; group I, fresh cases without any treatment; group II, recurrent or chronic cases; group III, cases with sequelae as a result of OME.
    1) In group I, the entire middle ear cavity was occupied with material of soft-tissue density in 18 out of 21 ears. The incidence of soft-tissue density was 100% in the mastoid air cells, 95% in the mastoid antrum, 93% in the attic and 88% in the tympanic cavity. The percentage thus rose with the distance from the tympanic cavity.
    2) There was no significant difference in the incidence of soft-tissue density between groups I and II.
    3) In group III, the mastoid air cells showed density, while the other regions had adequate air-containing spaces.
    4) Even after myringotomy and aspiration of the fluid in group I, density was found in the mastoid air cells in 100% of the cases. Density in the mastoid antrum, attic and tympanic cavity was present in 43%, 21% and 21% of the cases, respectively. These results suggest that lesions are likely to persist in regions away from the orifice of myringotomy and that this therapy can not eliminate all of the lesions. In group II, the soft-tissue density in the middle ear was eliminated by myringotomy better than in group I.
    5) The effect of ventilating tubes on the mastoid air cells was not determined and requires further studies.
  • 鵜飼 幸太郎, 坂倉 康夫, 山際 幹和, 間島 雄一, 三吉 康郎
    1984 年 77 巻 8 号 p. 1573-1584
    発行日: 1984/08/01
    公開日: 2011/11/04
    ジャーナル フリー
    The results of surgery on 163 ears from 1978 to 1983 were studied. Of the 127 patients who answered our questionnaire, 20.1% complained of ear discharge and 24.8% of these had hearing deterioration. Of the total of 161 ears, which were examined by otoscopy and pure-tone audiometry, 44.7% underwent surgery for cholesteatoma; 45.4% for chronic suppurative otitis media; 5.9% for tuberculosis of the middle ear. Of those ears, 88 were treated with intact canal wall tympanoplasty, 30 ears with classical tympanoplasty, and 43 ears with reconstructed canal wall tympanoplasty. Perforation of the reconstructed ear drum recurrenced in 15.7% and ear discharge in 18.1% of the total: in 19.8% of the ears treated with intact canal wall tympanoplasty, in 28.9% of those with reconstructed canal wall tympanoplasty, and in 33.3% of those with classical tympanoplasty. Long-term hearing results were satisfactory; only 9.5% of the patients had a deterioration of hearing postoperatively while in 59.5% hearing was improved.
  • 宮本 永祥, 折田 洋造, 山本 英一, 稲垣 千果夫
    1984 年 77 巻 8 号 p. 1585-1590
    発行日: 1984/08/01
    公開日: 2011/11/04
    ジャーナル フリー
    The incidence of cancer in the paranasal sinuses is about 25% of the malignant tumors of the head and neck region.
    Most of them are squamous cell carcinomas, but adenocarcinoma is also recognized.
    —We have treated three patients with adenocarcinoma in the nasal cavity and paranasal sinuses.
    1) Case 1: A 70-year-old man treated by total maxillectomy and radiation has been alive for six years.
    2) Case 2: A 49-year-old man treated by only partial maxillectomy has been alive for four years and one month.
    3) Case 3: A 25-year-old man treated by chemo-radio-surgical therapy, died of recurrence and general metastasis.
    Surgical therapy should be tried, because radiation is not completely effective, except in cases of adenoacanthoma.
  • 小山 恵三, 妹尾 淑郎, 内藤 雅夫, 鈴木 昭男, 戸田 富貴, 石原 正健, 岩田 重信
    1984 年 77 巻 8 号 p. 1591-1597
    発行日: 1984/08/01
    公開日: 2011/11/04
    ジャーナル フリー
    In 1983, the incidence of allergic rhinitis in our clinic increased, especially in August and September.
    We were interested in the response for this seasonal increased of nasal attacks.
    The subjects with severe attacks were studied clinically and skin tested with several antigens. The air pollens in front of clinic was examined for, and the temperature and weather changes were recorded.
    1) The most frequent antigens giving positive skin tests were Housedust, Comporsitae and Alternaria in this order.
    2) The most common pollens in August and September were Artemisia and various grass pollens.
    3) The reasons for the increased attacks in this period were considered to be pollens in the air and wide temperature swings.
  • 桜井 一生, 森 茂樹, 内藤 健晴, 岩見 公晴, 高須 昭彦, 岩田 重信
    1984 年 77 巻 8 号 p. 1599-1604
    発行日: 1984/08/01
    公開日: 2011/11/04
    ジャーナル フリー
    Case 1. A 37-year-old male complained of epistaxis and nasal obstruction on the left side. X-ray examination showed a tumor in the left nasal cavity, but the paranasal sinuses were clear. The tumor was removed, and the histopathological diagnosis was angiofibroma.
    Case 2. A 37-year-old female complained of epistaxis and nasal obstruction on the left side. The tumor was deep red with an irregular surface. X-ray examination showed clear paranasal sinuses. We removed the tumor under local anesthesia. The histopathological diagnosis was angiofibroma.
  • 長谷川 聡, 山岸 益夫, 中野 雄一
    1984 年 77 巻 8 号 p. 1605-1609
    発行日: 1984/08/01
    公開日: 2011/11/04
    ジャーナル フリー
    We have devised an instrument to obtain small biopsy specimens of human olfactory mucosa and did trial biopsies of 10 patients during nasal operations for chronic sinusitis under local or general anesthesia.
    The biopsy instrument was advanced through the naris along the septum to the olfactory cleft. The cutting edge was pressed against the olfactory area of the septum, and the instrument was carefully withdrawn with the mucosal specimen. This procedure was performed successfully with no adverse effects. On the average, about three blocks of specimens were obtained to find one that contained olfactory mucosa. There was minimal change but no distinctly abnormal finding in an olfactory mucosa specimen examined by electron microscope. This method may be useful for investigations of human olfactory dysfunction.
  • 門脇 敬一, 横山 道明, 辻田 哲朗, 神崎 裕士
    1984 年 77 巻 8 号 p. 1611-1616
    発行日: 1984/08/01
    公開日: 2011/11/04
    ジャーナル フリー
    Case 1. A 30-year-old male complained of swelling of the forehead and exophthalmus. He was treated with irradiation and chemotherapy, but died 18 months later.
    Cpse 2. A 60-year-old male complained of swelling of the forehead. He was succesfully treated with surgical excision, irradiation and chemotherapy and is living and well with no recurrence or metastasis 18 months later.
    The authors reviewed six cases of malingant lymphoma of the frontal sinus reported in Japan during the past 51 years. The mortality of malingant lymphoma of the parasinuses has been very high in Japan.
    Case 2 was treated with combined therapy with good results. It is thought that combined therapy is effective for malignant lymphoma of the frontal sinus.
  • 西本 力, 宮前 雅明, 甲田 嘉彦, 中西 理恵子, 太田 文彦
    1984 年 77 巻 8 号 p. 1617-1622
    発行日: 1984/08/01
    公開日: 2011/11/04
    ジャーナル フリー
    The patient was a 47-year-old male with dyspnea, clouding of consciousness and hoarseness. Under Macintosh laryngoscopy and fiberscopy, a large dark-red tumor was found narrowing the air way. Laryngofissure revealed an extended tumor from the false cord to the arytenoid area on the right side. The tumor was removed together with the surrouding normal tissues. Two points of normal tissue near the tumor were coagulated by an electric coagulator. The incision was performed between them, so there was little bleeding. The normal laryngeal mucosa, which had overlain the tumor, was preserved and replaced to cover the raw surface.
    Histological examination revealed hemangioma cavernosa.
  • 稲垣 則子, 山際 幹和, 坂倉 康夫, 三吉 康郎
    1984 年 77 巻 8 号 p. 1623-1630
    発行日: 1984/08/01
    公開日: 2011/11/04
    ジャーナル フリー
    McCune-Albright Syndrome is characterized by polyostotic fibrous dysplasia of bone, pigmented spots of the skin and sexual precocity, principally in females. The pathogenesis of this syndrome is not clear.
    The authors describe two cases of this syndrome. Both were 6-year-old girls with facial deformity who resembled each other. Thickened skull and cloudy paranasal sinuses were seen on conventional X-rays and computed tomography.
    The literature on this syndrome is reviewed with special reference to the diagnosis, prognosis and treatment of the condition.
  • 第三報 長期正円窓膜閉鎖後の内耳機能及び外リンパ酸素分圧
    笹 英彦, 山下 敏夫, 楊 光宗, 熊沢 忠躬, 永原 國彦
    1984 年 77 巻 8 号 p. 1631-1640
    発行日: 1984/08/01
    公開日: 2011/11/04
    ジャーナル フリー
    After closure of the round window membrane of guinea pigs by various adhesive agents (histoacryl, alonalfa and dental cement), inner ear function was observed by cochlear microphonics (CM) and action potential (AP). At the same time, perilymphatic oxygen tension in the scala tympani was measured by polarographic methods.
    In addition to these chronic experiments, dynamic changes of the perilymphatic oxygen tension were measured during the flow of air, pure oxygen and nitrogen under general anesthesia.
    1) CM and AP fell significantly after three weeks, but did not change just after or three days after closure of the round window membrane.
    2) The perilymphatic oxygen tension increased significantly after a flow of pure oxygen, but decreased after nitrogen.
    3) The perilymphatic oxygen tension of the closed side three weeks after closure of the round window membrane decreased to about 50% that of the non-closed side.
    We assume that these results were caused by the decrease of oxygen supply caused by closure of the round window membrane.
  • 加納 直行
    1984 年 77 巻 8 号 p. 1641-1658
    発行日: 1984/08/01
    公開日: 2011/11/04
    ジャーナル フリー
    正常モルモットに利尿剤 Furosemide と Glycerol を投与し, 蝸牛管内リンパ, 鼓室階外リンパ, 前庭階外リンパの各内耳液を採取して, 血清, CSFとともにNa, Kの微量定量を行ない次の結果を得た.
    1. 正常耳の鼓室階外リンパ, 前庭階外リンパのNa, K濃度は, 血清, CSFも含め各々, 固有の電解質構成を示した.
    2. Furosemide (15mg/kg) 静注で, Na濃度では, 鼓室階外リンパ, 前庭階外リンパの両外リンパに一過性の上昇が認められた. またK濃度でも両外リンパに上昇が認められた.
    Na濃度の上昇は Furosemide の利尿作用により脱水が生じたものと考えられた.
    3. Glycerol (1.0ml/kg) 静注で, Na濃度は, 鼓室階外リンパに一過性の上昇が認められた. K値では前庭階外リンパに上昇が示された.
    4. Glycerol (50w/v,12ml/kg) 経口では, 両外リンパ, 蝸牛管内リンパに持続的な上昇が認められ, K濃度でも両外リンパ, CSFに上昇が認められた.
    上記のグリセロール投与によるNa濃度の上昇は, 浸透圧効果にもとずく脱水によってもたらされたものと考えられた.
    上記の条件で, 利尿剤 Furosemide と Glycerol を投与すると, 内耳液には脱水が生じることが判明した.
    さらに, メニエール病 (内リンパ水腫) の診断という臨床の面からみると, 今回のグリセロールの経口投与の実験結果は, 臨床上, 内リンパ水腫症例に対するグリセロールテストの結果と時間的関係は一致することがわかった.
    また, メニエール病の治療から考えると, 内耳液と血清の浸透圧差が長時間持続する経口投与の方が, 優利であることが示された.
  • 走査電顕的観察
    菊屋 義則
    1984 年 77 巻 8 号 p. 1659-1680
    発行日: 1984/08/01
    公開日: 2011/11/04
    ジャーナル フリー
    Morphological changes of the olfactory epithelium in the mouse due to aging, formaldehyde gas and sectioning of the fila olfactoria were studied by scanning electron microscopy.
    In the normal olfactory epithelium many cells with stereocilia like microvilli were observed. These cells resembled the fifth cell of the cat found by Andres (1969) and appeared to be mechano-receptors in the olfactory epithelium.
    Morphological changes due to aging were characterized by increase of the respiratory ciliated cells in the olfactory region and retreat of the olfactory epithelium at its boundary with the respiratory epithelium.
    The olfactory epithelium was variously affected after exposure to formaldehyde gas. In areas with severe damage the supporting cells degenerated early. This area regenerated to respiratory ciliated epithelium 14 days after exposure. Areas in which the supporting cells were not affected finally regenerated to olfactory epithelium. Transformation to ciliated cells in the olfactory region after formaldehyde gas exposure suggests that the basal cells of the respiratory and olfactory epithelium and the duct cells of Bowman's gland might be the stem cells of regenerated ciliated cells.
    Neuronal degeneration after sectioning of the fila olfactoria was recognized one day after surgery, and regeneration was noted 14 days after axonotomy. Regeneration to the normal surface structure of the olfactory epithelium was observed 56 days after axonotomy, but regeneration of the whole surface was still imcomplete at this stage. Morphological changes in the surface of the supporting cells were also recognized after surgery, but these findings were probably caused by reactive changes due to disappearance of the mat of the olfactory cilia.
    In several specimens a wide olfactory region was covered with respiratory ciliated epithlium after axonotomy, but it is questionable that these transformations were produced only by sectioning of the fila olfactoria.
  • 今井 昭雄, 野々村 直文, 中野 雄一
    1984 年 77 巻 8 号 p. 1681-1686
    発行日: 1984/08/01
    公開日: 2011/11/04
    ジャーナル フリー
    Tissue adhesion with highly concentrated human fibrinogen was used in 21 ear operations: seven cases of mastoid obliteration, ten canal wall reconstructions, two fascia grafts and three ossicular reconstructions.
    Stabilization of grafted bone and fascial tissue makes subsequent operative manipulation easier and makes the survival of the grafted materials more certain. Thus, this tissue adhesive is very convenient and easy to use. Neither systemic nor local side effects were observed, and the postoperative clinical course was favorable. This human fibrin tissue adhesive can be recommended for use in middle ear surgery.
  • ホスホマイシンを中心として
    朴澤 孝治, 湯浅 涼, 神林 潤一
    1984 年 77 巻 8 号 p. 1687-1691
    発行日: 1984/08/01
    公開日: 2011/11/04
    ジャーナル フリー
    Microorganisms were cultured from 164 specimens of aural discharge from patients with chronic otitis media, and their sensitivity to antibiotics was tested. Staphylococcus aureus, including AMPC- and ABPC- resistent strains (58%) and Pseudomonas aeruginosa were the main pathogens of chronic otitis media. Of the oral antibiotics tested, fosfomicin showed the highest antibacterial activity against most of the isolated strains.
  • 野末 道彦, 米山 正美, 鈴木 悟
    1984 年 77 巻 8 号 p. 1693-1701
    発行日: 1984/08/01
    公開日: 2011/11/04
    ジャーナル フリー
    Ifenprodil (セロクラール) をメニエール病をはじめとするめまい症例37例に使用し, その自覚症状および他覚所見の経過を観察した.
    その結果は次の通りであった.
    1. 疾患別に効果を検討した結果, メニエール病の67%, メニエール病類似症の56%, 良性発作性頭位眩量症の73%, 椎骨脳底動脈循環不全症の100%に有効であった.
    2. めまい, およびそれに伴ういくつかの自覚症状に対する効果をみたところ, めまいの頻度に対しては73%, めまいの程度に対しては86%, 平衡障害に対しては81%, 悪心, 嘔吐に対しては88%, 頭重感ならびに頭痛に対しては79%, 肩こりに対しては73%の効果を示した.
    3. 他覚所見は多くの症例にみられたわけではないが, 認められた他覚所見の大部分は消失した.
    4. 本剤の副作用は全く認められなかった.
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