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95 巻, 1 号
選択された号の論文の17件中1～17を表示しています
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伊藤 壽一2002 年 95 巻 1 号 p. 1-5
発行日: 2002/01/01
公開日: 2011/11/04
ジャーナル フリーSince the development of clinical genetic medicine, we have needed the knowledge and ability to provide genetic counseling in the Department of Otolaryngology.
Genetic counseling for congenital hearing loss plays an especially important role in medicine. We have encountered more than 40 such cases in our hospital. Counseling for congenital hearing loss is very complex. Even if both parents are affected by deafness, the risk of their children developing deafness is around 10 per cent, which is very low compared with other genetic disorders. Before the discovery of the genes responsible for hearing loss, it was possible to predict hearing loss in the next child only on the basis of previous data. However, in the past 10 years, many genes responsible for congenital hearing loss have been identified. In fact genetic diagnosis of hearing loss is possible using molecular techniques. Thus, genetic counseling is more complicated than that for other diseases. As is the case for other diseases, ethical problems are deeply involved. We discuss not only the molecular technique but also the importance of genetic counseling for the happiness of the patient.抄録全体を表示PDF形式でダウンロード (676K) -
竹田 泰三2002 年 95 巻 1 号 p. 6-7
発行日: 2002/01/01
公開日: 2011/11/04
ジャーナル フリー -
三浦 正子, 下郡 博明, 中野 智子, 山下 裕司, 柏木 史郎2002 年 95 巻 1 号 p. 9-14
発行日: 2002/01/01
公開日: 2011/11/04
ジャーナル フリーA case of bilateral dilatation of the internal auditory canal without acoustic tumors, which was the so-called patulous internal auditory canal, is reported. The patient was a 12-year-old boy with bilateral sensorineural hearing loss, canal paresis in the left ear, anal atresia, epilepsy, mental retardation, and A-V block.
Radiographs showed that the maximum diameter of the internal auditory canal was 12.8 mm on the left and 16.3 mm on the right. CT and MRI showed no evidence of an intracanalicular mass. Diffusion-weighted imaging was useful for a definitive diagnosis. No epidermoid cyst was present in the internal auditory canal.抄録全体を表示PDF形式でダウンロード (5751K) -
―鼓室処置の有効性とその評価―小出 純一, 萩原 啓二, 米倉 英明, 山本 肇, 中島 務2002 年 95 巻 1 号 p. 15-18
発行日: 2002/01/01
公開日: 2011/11/04
ジャーナル フリーWe evaluated the effectiveness of topical treatment including aspiration of otorrhoea, cleaning with cotton appli-cators and saline irrigation of external and midle ear in acute otitis media and chronic otitis media. The cases were divided into group A (with topical treatment) and group B (without topical treatment) in a random manner. In both groups the patients received otic drops for 4 days at the clinic or at home. The clinical course was significantly better in group A than group B.抄録全体を表示PDF形式でダウンロード (468K) -
―鼻処置の有用性とその評価―渡辺 忠彦, 大井 益一, 征矢 野薫, 平松 隆, 水谷 泰吉, 水田 啓介, 伊藤 八次2002 年 95 巻 1 号 p. 19-29
発行日: 2002/01/01
公開日: 2011/12/12
ジャーナル フリーThe aim of this study was to investigate the usefulness of topical treatments for nasal cavity in nasal diseases. The effects of topical treatments for the nasal cavity were evaluated based on the rhinoscopic findings and subjective symptoms reported by physicians of cooperating clinics in Gifu prefecture with the same protocol, and the patients' satisfaction degree was also evaluated from questionnaires completed by patients.
Subjective symptoms and rhinoscopic findings were compared before and after the topical treatment. In subjective symptoms, the evaluation score decreased to 55.7% of that of before management. In objective rhinoscopic findings, the score decreased to 45.2% of that of before management. Thus, a marked decrease in symptoms and findings was observed as a results of topic treatments. Moreover, patients' satisfaction with treatment was high.抄録全体を表示PDF形式でダウンロード (7217K) -
―鼻ネブライザー療法の有用性とその評価―荘司 邦夫, 間島 雄一2002 年 95 巻 1 号 p. 31-37
発行日: 2002/01/01
公開日: 2011/11/04
ジャーナル フリーThe aim of this study was to investigate the efficacy of nasal nebulizer therapy and to elucidate how nasal nebulizer therapy was evaluated by medical professionals using a questionnaire survey to otolaryngologists in Mie prefecture. Among the doctors who answered the questionnaire, 96% and 94% used nasal nebulizers to treat acute sinusitis and chronic sinusitis, respectively, and the therapy was highly rated by the doctors.
To investigate the efficacy of nasal nebulizer therapy in an objective clinical setting, we treated 145 patients (63 children, 82 adults) with chronic sinusitis by nasal nebulizer twice a week for over two months in 18 hospitals in Mie prefecture. We then determined the general effectiveness of the therapy against subjective symptoms as well as objective symptoms. The results showed that the nasal nebulizer therapy was effective in 17% of the child patients and in 40% of the adult patients. The efficacy rate was higher than that for oral treatments such as enzyme preparations.抄録全体を表示PDF形式でダウンロード (4171K) -
石田 芳也, 今田 正信, 国部 勇, 林 達哉, 野中 聡, 原渕 保明2002 年 95 巻 1 号 p. 39-43
発行日: 2002/01/01
公開日: 2011/11/04
ジャーナル フリーSarcoidosis is a systemic disease of unknown cause. Most cases involve the lungs, lymph nodes, skin, and eyes. However, sarcoidosis with nasal symptoms is less frequent. We present two cases of nasal sarcoidosis with nasal obstruction. One patient was a 29-year-old female with nasal obstruction, skin lesions, neck lymph node swelling, and BHL. The other patient was a 31-year-old female who was diag-nosed with sarcoidosis with skin lesions and BHL in 1994. She presented to our hospital with complaints of nasal obstruction. Both patients' pathological findings for the nasal mucosa were granulomatous structure without necrosis, and were diagnosed with nasal sarcoidosis. The first patient was treated with local steroids and the nasal symptoms nearly disappeared completely. The other patient was treated with surgical management and local steroids, and the nasal symptoms were controlled.抄録全体を表示PDF形式でダウンロード (8392K) -
荻野 敏, 榎本 雅夫, 和田 光雄2002 年 95 巻 1 号 p. 45-50
発行日: 2002/01/01
公開日: 2011/11/04
ジャーナル フリーSeveral reports indicate that the severity of perennial allergic rhinitis is related to levels of dust-mite allergens. In this study, the levels of dust-mite allergens measured in the homes of 13 people with allergic rhinitis and 10 healthy volunteers. Dust specimens were collected with a vacuum cleaner and analyzed for the presence of major mite allergens (Der 1=Der p1+Der f1, Der 2=Der p2+Der f2) by using ELISA. Levels of Der 1 were higher in bedclothes, in bedrooms, and on family room floors. There were no differences between the homes of the 13 people with allergic rhinitis and the 10 healthy volunteers. No association was found between levels of dust-mite allergens and the severity of nasal symptoms. Although the levels of mite allergens increased in most of homes 2 months after cleaning, there was an insignificant tendency for improvement in nasal symptoms in homes with decreased levels 2 months after cleaning.抄録全体を表示PDF形式でダウンロード (841K) -
小川 武則, 鈴木 直弘, 沖津 卓二2002 年 95 巻 1 号 p. 51-60
発行日: 2002/01/01
公開日: 2011/11/04
ジャーナル フリーIn this study we reviewed the clinical features, diagnoses and treatments of 232 cases of nasal bone fracture cases treated at our department from January 1994 to June 2000.
A marked predominance of males in the age range of 10-29 years was noted. Analysis of the causes of the nasal fractures were attributed to fighting (66 cases), traffic accidents (64 cases), sports (56 cases) and others (46 cases).
The external appearance of nasal fractures were divided into 5 types, 85 cases of the displacement type, 27 cases of the depressed type, 32 of the mixed type, 56 of the non-deformation type and 32 of the unclassified type because of facial swelling.
The sensitivity of conventional X-ray examination in identifing nasal fractures was 75.6%.
Computed tomography scan (CT scan) was performed in 196 patients and showed that the middle and lower portions of nasal bones were fractured more easily than those of the upper portion.
Nasal septum fracture occurred in 22 cases (11.2%). Other facial fractures combined with nasal fracture were found in 40 cases (20.4%).
The type of combined fracture depended on the cause of the injury, for example, the combination of nasal and blow-out fracture was often caused by fighting, and many combined fractures of more than two facial bones resulted from traffic accidents.
A total of 83 patients (35.8%) received reduction of the nasal bone fractures under general anaesthesia.
The measurement of irradiation of each radiological examination revealed that the exposed dose of the newest model CT was similar to that of the conventional X-ray examination and tomography.抄録全体を表示PDF形式でダウンロード (1545K) -
柳内 充, 林 達哉, 片田 彰博, 片山 昭公, 石田 芳也, 太田 亮, 今田 正信, 野中 聡, 原渕 保明, 三代川 斉之2002 年 95 巻 1 号 p. 63-68
発行日: 2002/01/01
公開日: 2011/11/04
ジャーナル フリーWe report a case of malignant myoepithelioma that developed in the hard palate. A 70-year-old woman diagnosed with pleomorphic adenoma of the hard palate was transferred to our clinic for surgical treatment of the tumor. The pathological diagnosis of a biopsy was pleomorphic adenoma. The tumor was round and solid, with partial epithelial loss. There were no palpable neck lymph nodes. CT indicated that the tumor was limited to the hard palate without bone destruction. The operation was performed. The tumor was not infiltrative and easy to exfoliate. The pathological diagnosis was malignant myoepithelioma. After the operation, no recurrence was observed for 18 months.抄録全体を表示PDF形式でダウンロード (8602K) -
吉村 勝弘, 今中 政支, 愛宕 利英, 中村 雅宏, 牧本 一男, 竹中 洋2002 年 95 巻 1 号 p. 69-74
発行日: 2002/01/01
公開日: 2011/11/04
ジャーナル フリーSalivary duct carcinoma is an uncommon, relatively unknown, and clinically aggressive carcinoma of salivary origin. Recently, we treated a rare case of salivary duct carcinoma arising from the accessory parotid gland. The patient was a 68-year-old male who complained of left cheek swelling. The mass was located in left mid-cheek. Fine needle aspiration biopsy and open biopsy of the mid-cheek mass revealed malignant cells, but the pathological diagnosis was not settled. The mass in the mid-cheek was resected en-block including the buccal branches of the facial nerve, the superficial parotid gland, a part of the masseter muscle, and the skin right above the tumor. A pathological examination identified comedo necrosis and a final diagnosis of salivary duct carcinoma was made. The patient was treated with postoperative radiation therapy and has been free of tumors for 10 months.抄録全体を表示PDF形式でダウンロード (8007K) -
篠原 尚吾, 山本 悦生, 田辺 牧人, 藤原 敬三, 渡辺 太志, 菊地 正弘2002 年 95 巻 1 号 p. 75-80
発行日: 2002/01/01
公開日: 2011/11/04
ジャーナル フリーIn the present study, we retrospectively investigated states of occult metastases and lymph nodes with recurrent mesopharyngeal squamous cell carcinoma (MPSCC) to find an appropriate mode of neck dissection for MPSCC.
Thirty-one patients with MPSCC who underwent neck dissection or were diagnosed with a recurrence in the neck lymph nodes following curative therapy were available for the present study. In cases of NO MPSCC (9 cases), occult metastases and recurrent nodes were mostly limited to ipsilateral levels 1 to 3. One case with recurrence on the lower border (hypopharynx) in the primary region had a reccurred node at level 6. In cases with a single swelling node (3 cases of N1 and 8 cases of N2a), metastases or recurrence never ocurred at level 5. In cases with multiple swelling nodes or a large (>6 cm) node (8 cases of N2b, 1 case of N2c and 2 cases of N3), metastases were spread through ipsilateral levels 1 to 5 but never occurred in contralateral level 5. In cases of lateral wall type, residual lymph node metastases after curative radiation therapy were observed in 3 cases. Consequently, we conclude that ipsilateral level 1 to 4 neck dissection is appropriate for NO mesopharyngeal cancer, ipsilateral or bilateral level 1 to 4 neck dissection for Nl and N2a cases, and ipsilateral level 1 to 5 and contralateral level 1 to 4 neck dissection for more than N2a cases. We also conclude that it is necessary in some cases of lateral wall type to perform neck dissection after curative radiotherapy.抄録全体を表示PDF形式でダウンロード (755K) -
硲田 猛真, 齊藤 優子, 瀬野 悟史, 十河 英世, 池田 浩己, 藤村 聡, 嶽 良博, 榎本 雅夫2002 年 95 巻 1 号 p. 81-85
発行日: 2002/01/01
公開日: 2011/11/04
ジャーナル フリーCombination chemotherapy including 5FU and carboplatin (CBDCA) with methotrexate (MTX) and leucovorin (LV) as biochemical modulation was performed on patients with head and neck cancer. A total of 32 patients were treated in the order of MTX, continuous 5FU infusion and LV injection, CBDCA. 24 of the 32 patients were concurrently treated with radiation therapy. Treatment-associated toxicity was significant, including mucositis, myelosuppression and body weight losses, but they were within acceptable limits. The 5-year survival rates calculated using Kaplan-Meyer methods were 41.3%.抄録全体を表示PDF形式でダウンロード (2348K) -
宮本 篤志, 深澤 啓二郎, 高安 定, 阪上 雅史2002 年 95 巻 1 号 p. 87-92
発行日: 2002/01/01
公開日: 2011/11/04
ジャーナル フリーWe performed a statistical study of outpatients visiting the Department of Otolaryngology at Hamasaka Public Hospital for an one year period from April 1998 to March 1999. A total of 455 of 1, 658 patients (27.4%) were in the 0 to 9 years age group, which was the highest number. A total of 849 of the 1, 658 patients (51.2%) had otogenic diseases.
The incidence of acute otitis media was highest in the 0 to 9 years age group. Sensorineural hearing loss, most of which was diagnosed as presbycusis, was most common in the over 65 age group.抄録全体を表示PDF形式でダウンロード (662K) -
―T細胞の抗原反応性からみた作用機序―鷲尾 有司2002 年 95 巻 1 号 p. 93-104
発行日: 2002/01/01
公開日: 2011/11/04
ジャーナル フリーThis study was designed to investigate the working mechanism of Immunotherapy at the level of T cell reactivity to the allergen and to determine possible predictable factors of successful Immunotherapy for allergic rhinitis. Peripheral blood mononuclear cells were obtained from 60 patients with perennial allergic rhinitis due to Dermatophagoides farinae, and were cultured with Der f 1 for 96 hours to determine the cytokine synthesis. Forty-six patients were treated for 2 years with Immunotherapy using standardized D. farinae extracts, and the remainder were treated with antiallergic medications. Clinical improvement was obtained in more than 90% of the patients treated with Immunotherapy. IL-5 synthesis was significantly reduced in the patients treated with Immunotherapy. However, such reduction was not observed in the patients treated with antiallergic medications. The suppression of the allergen-induced IL-5 synthesis was most likely to be involved in the working mechanism of Immunotherapy. However, this study has failed to determine predictable factors of successful Immunotherapy for allergic rhinitis.抄録全体を表示PDF形式でダウンロード (1841K) -
渡邉 昭仁, 金谷 健史, 古澤 慎一, 藤村 裕, 木村 裕, 斎藤 喜澄2002 年 95 巻 1 号 p. 105-109
発行日: 2002/01/01
公開日: 2011/11/04
ジャーナル フリーWe evaluated the efficacy of Byakkokaninjintou in children with recurrent parotitis. Three children were given Byakkokaninjintou in the acute stage of recurrent parotitis. All children recovered in 3 to 4 days and continued to receive Byakkokaninjintou for three months. After administration, no children have parotitis. We think that Byakkokaninjintou is effective for the treatment of recurrent parotitis in children.抄録全体を表示PDF形式でダウンロード (4375K) -
伊藤 八次2002 年 95 巻 1 号 p. 110-111
発行日: 2002/01/01
公開日: 2011/11/04
ジャーナル フリーPDF形式でダウンロード (270K)
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