Kanzo
Online ISSN : 1881-3593
Print ISSN : 0451-4203
ISSN-L : 0451-4203
Search
Advanced search
OR
Browse
Search
Volume 16, Issue 5
Displaying 1-11 of 11 articles from this issue
Show all abstracts
    • |<
    • <
    • 1
    • >
    • >|
  • Acid Mucopolysaccharides in the Liver Tissues from Patients with Hepatic Cancer
    Junnosuke KOJIMA, Nobuto NAKAMURA, [in Japanese], Haruo TANIGUCHI, Kiy ...
    1975 Volume 16 Issue 5 Pages 259-264
    Published: May 25, 1975
    Released on J-STAGE: July 09, 2009
    DOIhttps://doi.org/10.2957/kanzo.16.259
    JOURNAL FREE ACCESS
    Show abstractHide abstract
    Acid mucopolysaccharides (AMPS) in the livers obtained from patients with hepatie cancer were investigated, using the methods of enzymatic analysis and electrophoresis.
    A remarkable increase in total amount of AMPS, hyaluronic acid and chondroitin sulfates was observed in both hepatocellular and cholangiocellular carcinomas and metastatic hepatic carcinomas, compared with that in healthy human liver. This increase was most remarkable in cholangiocellular carcinoma. Total amount of AMPS was increased significantly also in hepatic tissue adjacent to the tumor. The constituents which showed a marked increase in cirrhotic liver were chondroitin sulfate and dermatan sulfate different from those in hepatic carcinoma. The electrophoretic findings revealed that hyaluronic acid of hepatic carcinoma was different from that of healthy liver, and that a kind of glycoprotein was present in the CPC fraction of adenocarcinomas as a alcian blue positive slow band.
    These results appear to indicate that both quantitative and qualitative abnormalities of AMPS in hepatic carcinoma differ from that in cirrhotic liver and have some biological significance in cancerous tissues.
    View full abstract
    Download PDF (1809K)
  • Studies on Sterol-ester Hydrolase in a Rat and Human Liver.
    Tadao SAKAMOTO
    1975 Volume 16 Issue 5 Pages 265-275
    Published: May 25, 1975
    Released on J-STAGE: July 09, 2009
    DOIhttps://doi.org/10.2957/kanzo.16.265
    JOURNAL FREE ACCESS
    Show abstractHide abstract
    Sterol-ester hydrolase (E. C. 3. 1. 1. 13) has been prepared from various tissues such as rat liver, rat pancreas, rat brain, human placenta and human liver, however an activity of this enzyme has been considered to be very low. In contrast, the present communication reports that a high sterol-ester hydrolase activity is found in the microsomal fraction of rat and human liver after being treated with Triton X-100 or lysolecithin.
    The optimum pH of the enzyme is found to be approximately 6.6.
    Activation of sterol-ester hydrolase with Triton X-100 has been considered to be accomplished by solubilizing the enzyme from the microsomal fraction, whereas lysolecithin solubilizes the enzyme in only partially, though it activates the enzyme to similar extent as does Triton X-100. It has been thus suggested that activation mechanism of the enzyme with lysolecithin might be distinguished from that of Triton X-100.
    Among various cholesterol esters tested, cholesterol acetate has been the most suitable substrate.
    View full abstract
    Download PDF (536K)
  • Clinical and Pathological Liver Abnormalities in Alcoholics
    Kunitaro YAMAGUCHI, Tomohiko SETOGUCHI, Yukio KUSUMOTO, Tatsuo MUNEHIS ...
    1975 Volume 16 Issue 5 Pages 276-283
    Published: May 25, 1975
    Released on J-STAGE: July 09, 2009
    DOIhttps://doi.org/10.2957/kanzo.16.276
    JOURNAL FREE ACCESS
    Show abstractHide abstract
    Thirty-four patients who drank more than 80gm daily during the periods of 10 years or above were selected in order to study clinico-patholoigcal effects of alcohol on the liver. Their diagnosis was confirmed by liver biopsy and divided histologically into group A (17 patients with liver cirrhosis or pre-cirrhosis) and group B (17 patients with non-cirrhosis).
    1) Physically, the group A was predisposed to hepatomegaly, jaundice, vascular spider and ascites when compared with group B.
    2) The group A showed abnormality in BSP, TTT, ZST, AL-P and transaminase more frequently than group B. GOT/GPT was apt to be over 1 in group A.
    3) Study estimated a relationship between alcohol consumption and histological findings of the liver and suggested that heavy drinker who had drunk more than 200gm daily during the periods of 15 years or above tended to be included in group A.
    4) Electron microscopic study demonstrated crystalloid materials (periodicity 160A) in the cytoplasmic materials as a special finding.
    5) Serial liver biopsies in one case demonstrated a four years' course of the disease reaching to postnecrotic cirrhosis.
    View full abstract
    Download PDF (3354K)
  • Primary Leiomyosarcoma of the Liver-An Autopsy Case-
    Noboru HATAKEYAMA, Kazuomi NAKAZAWA, Ryoichi SATODATE, Sukemoto KATSUR ...
    1975 Volume 16 Issue 5 Pages 284-289
    Published: May 25, 1975
    Released on J-STAGE: July 09, 2009
    DOIhttps://doi.org/10.2957/kanzo.16.284
    JOURNAL FREE ACCESS
    Show abstractHide abstract
    This is a report of one case of a 15 year-old female with primary leiomyosarcoma of the liver. The patient noted the gradual onset of a sensation of fullness in the upper abdomen. An enlarged liver of the patient observed by one doctor, and therefore she was admitted to our hospital.
    Physical and laboratory findings showed indications of primary carcinoma of the liver. The patient lost her consciousness after repeated hematemesis and expired after admission during two months.
    At autopsy, the liver weighed 10, 100 grams and consisted of a large brownish and gelatin-like tumor tissue and several smaller milk-white nodules.
    Microscopically the forms of the tumor cells were irregular in size and shape, which were composed of interlacing bundles of spindle-shaped cells arranged in a whorled pattern. Strikingly myofilaments in the tumor cells were noted under the electron microscopy.
    View full abstract
    Download PDF (2135K)
  • [title in Japanese]
    [in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...
    1975 Volume 16 Issue 5 Pages 290
    Published: May 25, 1975
    Released on J-STAGE: July 09, 2009
    DOIhttps://doi.org/10.2957/kanzo.16.290
    JOURNAL FREE ACCESS
    Download PDF (77K)
  • [title in Japanese]
    [in Japanese], [in Japanese], [in Japanese], [in Japanese]
    1975 Volume 16 Issue 5 Pages 291
    Published: May 25, 1975
    Released on J-STAGE: July 09, 2009
    DOIhttps://doi.org/10.2957/kanzo.16.291
    JOURNAL FREE ACCESS
    Download PDF (800K)
  • [title in Japanese]
    [in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...
    1975 Volume 16 Issue 5 Pages 292
    Published: May 25, 1975
    Released on J-STAGE: July 09, 2009
    DOIhttps://doi.org/10.2957/kanzo.16.292
    JOURNAL FREE ACCESS
    Download PDF (792K)
  • [title in Japanese]
    [in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...
    1975 Volume 16 Issue 5 Pages 293
    Published: May 25, 1975
    Released on J-STAGE: July 09, 2009
    DOIhttps://doi.org/10.2957/kanzo.16.293
    JOURNAL FREE ACCESS
    Download PDF (797K)
  • [title in Japanese]
    [in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...
    1975 Volume 16 Issue 5 Pages 294
    Published: May 25, 1975
    Released on J-STAGE: July 09, 2009
    DOIhttps://doi.org/10.2957/kanzo.16.294
    JOURNAL FREE ACCESS
    Download PDF (801K)
  • [title in Japanese]
    [in Japanese], [in Japanese], [in Japanese]
    1975 Volume 16 Issue 5 Pages 295
    Published: May 25, 1975
    Released on J-STAGE: July 09, 2009
    DOIhttps://doi.org/10.2957/kanzo.16.295
    JOURNAL FREE ACCESS
    Download PDF (61K)
  • [title in Japanese]
    1975 Volume 16 Issue 5 Pages 296-320
    Published: May 25, 1975
    Released on J-STAGE: July 09, 2009
    DOIhttps://doi.org/10.2957/kanzo.16.296
    JOURNAL FREE ACCESS
    Download PDF (1261K)
    • |<
    • <
    • 1
    • >
    • >|
feedback
 Top