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Volume 18, Issue 12
Displaying 1-8 of 8 articles from this issue
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II. Change in Susceptibility of Mice to Bacterial Endotoxin following Infection with BCG or Unclassified MycobacteriaAkira INUI1963 Volume 18 Issue 12 Pages 449-454
Published: December 25, 1963
Released on J-STAGE: June 17, 2011
JOURNAL FREE ACCESSChange in susceptibility of mice to bacterial endotoxin was summerized as follows:
1. Mice pretreated with unclassified mycobacteria increased the susceptibility to bacterial endotoxin as BCG-immunized mice.
The increase in susceptibility to bacterial endotoxin was conspicuous in order of photochromogen P-16, scotochromogen Watanabe, non-photochromogen Ueda. Non-photochromogen 121326 strain did not increase the susceptibility to endotoxin.
2. The increase in susceptbility to bacterial endotoxin following infection with unclassified mycobacteria was associated with proliferative ability of infected strains in vivo, but BCG-immunized mice showed a remarkable increase in the susceptibility in spite of weak bacterial multiplication in organs.
3. There was no parallelism between the immunity reported in previous reports and the increase of susceptibility to bacterial endotoxin reported here.
4. Previous and present experimental results led to the conculusion that protective mechanism of unclassified mycobacteria to infection with human tubercle bacilli is different from that of BCG.View full abstractDownload PDF (1221K) -
I. The preparation of a antigenic polysaccharide from the heated cell extract of B. anthracisTsuyoshi BABA1963 Volume 18 Issue 12 Pages 455-457
Published: December 25, 1963
Released on J-STAGE: June 17, 2011
JOURNAL FREE ACCESS1. A antigenic substance was isolated from the heated cell extract of B. anthracis through trichloroacetic acid treatment, the removal of lipids by ether, aceton-, ammonium sulfate-fractionation and zone electrophoresis.
2. The substance was shown to be a single component by zone electrophoresis, ultracentrifugation and agar diffusion test.
3. The precipitating titer of the substance for anti-anthracis serum was positive in 2, 048×103fold dilution.
4. The substance was nonspecific in the sense that it reacted with anti-B. megatherium (B. cereus) and anti-B. subtilis serum.
5. The substance was positive in molisch and anthrone reaction and negative in protein and nucleic acid reaction; thus it was to be polysaccharide.View full abstractDownload PDF (539K) -
9. Studies on the Role of Purified Agglutinogen and Toxin in Intraperitoneal Infection and ImmunityTakuya ISHII1963 Volume 18 Issue 12 Pages 458-464
Published: December 25, 1963
Released on J-STAGE: June 17, 2011
JOURNAL FREE ACCESSThe antigenicity of purified toxin fraction and the nature of the immunity were investigated. From the experimental results using C57B1 or CF1 strain of mice which was proved to show relatively uniform infectious pattern, it was elucidated that agglutinogen played an important role in infection especially in invasiveness of the organisms, that is mice immunized with agglutinogen survived against challenge of 8 billions ofB. pertussis, although mice were lethal against the toxin equivalent to 2 or 4 billions of the organisms, whereas mice showed high resistance to the challenge of 8 billions of organisms alone. Those facts suggested that intraperitoneal infection was not only affected with toxin but also agglutinogen. Thus, it is suggested that the role of agglutinogen or toxin on the infection was somewhat different although the mice immunized with each component survived against the challenge of the live organisms. There are twc point of view concerning the activity of two component in infection ; that is the one is that the organisms cleared from peritoneal cavity as the results of inhibition of invasiveness in mice immunized with agglutinogen, the other is the importance of antitoxic immunity, since the toxin from larger amounts of organism, which was requested in intraperitoneal infection than in intracerebral or intranasal infection, affecting on leucocytes itself or humoral bactericidal mechanisms.View full abstractDownload PDF (1558K) -
Machiko SHIBUTAKE, Zensaku YOSHII1963 Volume 18 Issue 12 Pages 465-469
Published: December 25, 1963
Released on J-STAGE: June 17, 2011
JOURNAL FREE ACCESS12 strains of aerobic and 10 strains of anaerobic spore forming “thiaminase bacteria” -capable of producing extra cellular thiaminase-were isolated from the intestinal contents of 52 top-shells (Turbo cornutusSOLANDER), 6 of which contained both of aerobic and anaerobic “thiaminase bacteria”.
Their biological characteristics were compared with Bergey's Manual 1957 and traditional classification.
All strains of the aerobic “thiaminase bacteria” isolated were identified as belonging toBacillus thiaminolyticusand some of the anaerobic bacteria were closely related toClostridium sporogenesand others toClostridium parabotulinuni.
“Thiaminase I” was rarely detected from the intestinal contents, though the potent enzyme was always proved in the tissues of the internal organs.View full abstractDownload PDF (730K) -
1963 Volume 18 Issue 12 Pages 470-496
Published: December 25, 1963
Released on J-STAGE: June 17, 2011
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1963 Volume 18 Issue 12 Pages 497-505
Published: December 25, 1963
Released on J-STAGE: June 17, 2011
JOURNAL FREE ACCESSDownload PDF (1946K) -
1963 Volume 18 Issue 12 Pages 506-517
Published: December 25, 1963
Released on J-STAGE: June 17, 2011
JOURNAL FREE ACCESSDownload PDF (2408K) -
1963 Volume 18 Issue 12 Pages 518-531
Published: December 25, 1963
Released on J-STAGE: June 17, 2011
JOURNAL FREE ACCESSDownload PDF (2892K)
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