Nippon Saikingaku Zasshi
Online ISSN : 1882-4110
Print ISSN : 0021-4930
ISSN-L : 0021-4930
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Volume 40, Issue 4
Displaying 1-6 of 6 articles from this issue
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  • Development and present status of leptospiral vaccine and technology of vaccine production in China
    Ting-zuo CHEN
    1985 Volume 40 Issue 4 Pages 755-762
    Published: July 25, 1985
    Released on J-STAGE: February 19, 2009
    DOIhttps://doi.org/10.3412/jsb.40.755
    JOURNAL FREE ACCESS
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  • Outline of my research studies
    Takeshi TSUCHIYA
    1985 Volume 40 Issue 4 Pages 763-767
    Published: July 25, 1985
    Released on J-STAGE: February 19, 2009
    DOIhttps://doi.org/10.3412/jsb.40.763
    JOURNAL FREE ACCESS
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  • Genetic Control of immune response to Salmonella enteritidis antigen
    Norihisa ISHII, Kyoko OKUDA, Toyozoh TAKAHASHI, Kenji OKUDA
    1985 Volume 40 Issue 4 Pages 769-773
    Published: July 25, 1985
    Released on J-STAGE: February 19, 2009
    DOIhttps://doi.org/10.3412/jsb.40.769
    JOURNAL FREE ACCESS
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    Genetic control of immune responses against Salmonella enteritidis antigen was studied in mice by the estimation of delayed type hypersensitivity and antibody production.
    Observation of foot pad swelling using various congenic mice indicated that the reaction of delayed type hypersensitivity against S. enteritidis antigen was controlled by I-A subregion of H-2 region and the magnitude of the response in responder strains (I-Ad) was further controlled by non H-2 region. However, antibody production to the same antigen was not genetically controlled by H-2-linked immune response gene(s).
    Differences of genetic control between these two immune responses were also discussed.
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  • Biological activities of chemically-treated glycolipids from Salmonella minnesota Re-mutant
    Ken-ichi AMANO, Hiroshi FUJITA, Toshinobu SATO, Hiromi SASAKI, Yutaka ...
    1985 Volume 40 Issue 4 Pages 775-782
    Published: July 25, 1985
    Released on J-STAGE: February 19, 2009
    DOIhttps://doi.org/10.3412/jsb.40.775
    JOURNAL FREE ACCESS
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    Endotoxic glycolipid (ReGl) extracted from the heptose-less Re mutant of Salmonella minnesota was hydrolyzed with each of alkali or acid reagents, and the products were analyzed for several biological activities. Treatment of ReGl with NH2OH caused the liberation of all O-ester-linked fatty acids resulting in abrogation of toxicity (lethality to chick embryos), pyrogenicity, activity of Limulus amoebocyte lysate (LAL) gelation, ability of macrophage activation, and mitogenicity. ReGl treated with HCl, which splits off KDO and glycosidic phosphate, retained only two biological activities (LAL gelation activity and ability of macrophage activation). NaOH-treated or CH3COONa-treated ReGl possessed similar activities to those of untreated ReGl.
    On the other hand, ReGl or ReGl-HCl, in combination with cord factor, showed effectively regressive activities (about 50% cures) to the methylcholanthrene-induced tumor of rats, while ReGl-NH2OH showed only prolongation of life in comparison with that of tumor-bearing rats without treatment.
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  • Effects of Thiazolidine-4-carboxylic acid on Germ Tube Formation and L-[14C(U)] Proline Uptake in Candida albicans
    Yoshisato HAGIHARA, Tamaki CHO, Sachio HAYASHI, Naoko TSUNO, Hidenori ...
    1985 Volume 40 Issue 4 Pages 783-786
    Published: July 25, 1985
    Released on J-STAGE: February 19, 2009
    DOIhttps://doi.org/10.3412/jsb.40.783
    JOURNAL FREE ACCESS
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    Effects of thiazolidine-4-carboxylic acid (thioproline) on germ tube (GT) formation and L-[14C(U)] proline uptake in Candida albicans 1002 strain were investigated using a medium containing linoleic acid (10-2%), thioproline (10-2%), L-proline (10-2%) and NaHCO3 (10-2%). The results obtained were as follows: Thioproline accelerated GT formation at concentrations of 10-4 to 3×10-2% (maxima at 3×10-3 and 10-2%), and L-proline uptake at concentrations of 10-3 to 10-2% (maximum at 10-2%). Maximum of GT formatiom was 90%. However, both GT formation and L-proline uptake were inhibited by thioproline at a concentration of 10-1%.
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  • [title in Japanese]
    1985 Volume 40 Issue 4 Pages 787-793
    Published: July 25, 1985
    Released on J-STAGE: February 19, 2009
    DOIhttps://doi.org/10.3412/jsb.40.787
    JOURNAL FREE ACCESS
    Download PDF (1061K)
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