The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
102 巻, 1 号
選択された号の論文の12件中1~12を表示しています
  • JUNICHIRO NAGASAWA, TAIZO SUZUKI
    1970 年 102 巻 1 号 p. 1-12
    発行日: 1970年
    公開日: 2008/11/28
    ジャーナル フリー
    Ca uptake and efflux in the smooth muscle cell of guinea-pig taenia coli were estimated in the normal Krebs solution and in Krebs solution containing MnCl2. MnCl2 had no significant effect on the efflux of 45Ca in the concentration range between 1.0mM and 20mM. In the presence of 1mM MnCl2, adrenaline (up to 2.5×10-5g/ml) and tetrodotoxin (up to 2.5×10-3g/ml) had no significant effect on Ca efflux. But acetylcholine (up to 2.5×10-3g/ml) was found to increase the 45Ca efflux coincidentally with the tension development. Ca influx in normal NaCl Krebs solution was estimated to be 0.135p-mole/cm2•sec, and it was increased by 1.5 to 2 times in Na free sucrose Krebs solution. About 15% of total Ca influx was suppressed by 1.0mM MnCl2. This Ca content corresponding to 0.022p-mole/cm2•sec was tentatively attributed to the extra entry of Ca by the generation of action potential. But this amount proved to correspond to only 2% of the theoretically calculated necessary amount of divalent cation inflow accompanying the generation of action potential.
  • NOBUO YOSHII
    1970 年 102 巻 1 号 p. 13-21
    発行日: 1970年
    公開日: 2008/11/28
    ジャーナル フリー
    The continuous EEG recording was performed on 48 patients with cerebrovascular diseases before, during and after the injection of the contrast medium into the common carotid artery. The contrast medium was conditioned as equally as used in the cerebral angiography. Injections of Ringer's solution were made to the 48 cases in order to compare the results. The same examinations were performed also on 5 normal persons. 1) Significant changes in EEG were not observed in the normal persons. 2) EEG changes appeared in few cases with cerebrovascular diseases by injecting the Ringer's solution. 3) EEG alterations appeared in 33% of the cases with the cerebrovascular diseases during and/or after the injection of contrast medium. 4) Focal abnormality in EEG which was most frequently seen, appeared in 13 cases. It must be noted that the focal abnormality which had not been seen before, appeared after the injections, and that the extent of the appearance of the focal abnormality was considerably enlarged in some cases. Changes in frequency and amplitude of the basic waves were found in 4 cases. Bilateral spike appeared in one case. 5) The kinds and degrees of the clinical symptoms were not associated with the appearance of EEG abnormality. As to the relationship between the appearance rate of abnormal EEG and the kinds of the diseases, the rate in the cerebral hemorrhage showed insignificant differences from that in cerebrovascular disease, though the former was slightly lower. The local disturbance in the brain existed in most of the patients with the cerebrovascular diseases, though its symptom did not always appear. It is presumed in such instances that the metabolic disturbance becomes apparent and that EEG change is induced by the injection of the contrast medium in the cerebral angiography.
  • TOORU NAKAO, MASAO UMETSU, NOBUHIKO WATANABE, NAOKO KIKUCHI
    1970 年 102 巻 1 号 p. 23-31
    発行日: 1970年
    公開日: 2008/11/28
    ジャーナル フリー
    An increasing number of patients with atypical pneumonia were seen at the residents of the collective houses provided by a paper manufacturing company in the summer of 1967. Mycoplasma pneumoniae was established as the etiological agent in 80.5% of 36 patients who were subjected to serologic study. Familial infection was common. Outstanding symptom was cough. Skin rashes were noticed in 3 cases. Complement-fixing (CF) and indirect-hemagglutinating (IHA) antibody titers rose about 10 days after infection and remained unchanged for at least 2 months, but declined 9 to 12 months later. CF and IRA antibodies to Mycoplasma pneumoniae were both of the 19S and 7S types. There was an increase of 7S relative to 19S CF antibodies with time after the onset of illness, and almost all CF antibodies were 7S a year later. IHA antibodies were predominantly 19S globulins in various stages of illness.
  • TOSHIO FUJITA
    1970 年 102 巻 1 号 p. 33-35
    発行日: 1970年
    公開日: 2008/11/28
    ジャーナル フリー
  • YUTAKA MATSUYA, ISAO YAMANE
    1970 年 102 巻 1 号 p. 37-49
    発行日: 1970年
    公開日: 2008/11/28
    ジャーナル フリー
    In the course of cell establishment, neonatal hamster lung cells progressively acquired various new properties and they showed morphological and karyological changes. The cells became capable of growing infinitely in albumin-free medium and these cells also had an ability to grow at low inoculation densities. The neoplastic property of the cells developed more slowly than their chromosomal alteration into the heteroploid range. The established line could similarly propagate in both the standard medium and serum albumin medium, and consequently the growth promotion by bovine albumin became almost negligible.
  • YUTAKA MATSUYA, ISAO YAMANE
    1970 年 102 巻 1 号 p. 51-59
    発行日: 1970年
    公開日: 2008/11/28
    ジャーナル フリー
    Two cell lines of D cells derived from the same population of lung cells of newborn hamster were serially cultivated in media fortified with different kinds of albumin (bovine serum albumin and egg albumin) and were eventually developed into established lines. On the cultures carried in egg albumin medium, however, serum albumin became gradually growth-inhibitory, while the cells grown in serum albumin medium were not influenced by supplement of either serum albumin or egg albumin to the medium. That the two established lines had different cellular properties was confirmed by morphological and karyotype analysis.
  • TOORU NAKAO, RYOICHI MIURA, MITSUTAKE SATO
    1970 年 102 巻 1 号 p. 61-68
    発行日: 1970年
    公開日: 2008/11/28
    ジャーナル フリー
    ECHO 22 virus was isolated from fecal specimens of 20 out of 29 premature infants in 1964, and was again isolated from 9 out of 36 infants during 1966 and 1967 in the same premature nursery. The infants discharging ECHO 22 virus were asymptomatic or of slight symptoms of upper respiratory tract infection and of mild diarrhea. The sero-immunity against ECHO 22 virus in children in the same district revealed that about half the infants under 6 months of age had positive neutralizing antibody against ECHO 22 virus, and almost all children over a year of age had positive antibody. The evidence of transplacental infection due to ECHO 22 virus was not obtained. ECHO 22 virus in premature infants would probably be transmitted from infants to infants. The source of infection was not determined.
  • HIROSHI SUZUKI, KIMIO WATANABE, MORIO KASAI
    1970 年 102 巻 1 号 p. 69-80
    発行日: 1970年
    公開日: 2008/11/28
    ジャーナル フリー
    Measurement of intraluminal anorectal pressures and cineradiographic studies were carried out on 15 infants and children with Hirschsprung's disease and 18 patients who had undergone radical operation for the disease. The results were compared with those obtained from 50 normal infants and children. It was revealed that the chronic and severe constipation seen in Hirschsprung's disease was caused by lack of propulsive movement in aganglionic portion of the colon and absence of normal recto-sphincteric reflex. Studies on postoperative infants revealed that propulsive movement of the ano-rectrum and ordinary recto-sphincteric reflex were recovered in patients treated by rectal myotomy with colectomy or Lynn's rectal myectomy. On the other hand, recto-sphincteric reflex was not restored in those who had undergone Swenson's rectosigmoidectomy.
  • TSUNEO ARAKAWA, TAKASHI MIZUNO, YOSHIYUKI HONDA, TSUNENOBU TAMURA, AYU ...
    1970 年 102 巻 1 号 p. 81-90
    発行日: 1970年
    公開日: 2008/11/28
    ジャーナル フリー
    Maturation patterns of the EEG basic waves of breast-fed infants were studied longitudinally from 3 months to 29 months of life with special reference to their folate status. The basic waves of EEG were divided into ten bands (I-X bands) by means of an automatic analyzer specially adapted and ‘R’ =(E% of VIII+E% of IX)/(E% of II+E% of III) was used for an index of the evaluation of maturation patterns of the EEG basic waves. Serum folate levels of lactating mothers and of infants and urinary folate of infants were estimated at the time when the EEG was examined. The maturation of the EEG basic waves, expressed as the ‘R’, was definitely delayed in infants fed on mothers' milk whose serum folate levels were below the normal range. This tendency was observed to be kept over after the weaning period.
  • TAKASHI MIZUNO, NORIO YAMAUCHI, AYUKO WATANABE, MAYUKI KOMATSUSHIRO, T ...
    1970 年 102 巻 1 号 p. 91-98
    発行日: 1970年
    公開日: 2008/11/28
    ジャーナル フリー
    A simplified method for an evaluation of maturation patterns of the EEG waves of healthy infants under 12 months of age was reported. The EEG basic waves were divided into 10 bands according to frequency ranges (I-X bands). An averaged integrated voltage was calculated at each of the frequency bands (I-E%, II-E%, ....X-E%). When ‘R’=(E% of VIII+E% of IX)/(E% of II+E% of III) was claculated and plotted against the age in months, a linear figure was obtained which demonstrated a maturation pattern of the EEG basic waves of infants with advance in age.
  • TOSHIYUKI OZAKI, SECHIKO SASAKI, KATSURO IGARASHI
    1970 年 102 巻 1 号 p. 99-100
    発行日: 1970年
    公開日: 2008/11/28
    ジャーナル フリー
    The microvibration was recorded from the skin surface of the parietal region of the head and compared with the ballistocardiogram simultaneously recorded with a conventional technique. The results suggest the possibility that the microvibration recording from this region may be used in place of a conventional ballistocardiography.
  • TAKASHI NAKAMURA, KIMIO KONNO, TAKESHI MORONE, NOBORU TSUYA, MASAHIRO ...
    1970 年 102 巻 1 号 p. 101-102
    発行日: 1970年
    公開日: 2008/11/28
    ジャーナル フリー
    Angiographic methods with magnetic materials are described. Either carbonyl iron suspension was intravenously injected or a catheter with minute iron rings was inserted into the ventricle of the heart, and a magnetic force was applied to the cardiac region. X-ray cinematograph demonstrated the motion and thickness of the ventricular wall. The experiment was performed on the dog.
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