巻号一覧
108 巻 (1972)
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108 巻, 1 号
選択された号の論文の12件中1～12を表示しています
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TETSURO NISHIHIRA, GENSHICHIRO FUJII1972 年 108 巻 1 号 p. 1-7
発行日: 1972年
公開日: 2008/11/28
ジャーナル フリーThe lymphocyte-platelet reaction (MLPR) in various donor-recipient combinations in rats showed a nearly coincident relationship with the mixed lymphocyte culture reaction (MLC). The kidney cells had not enough stimulating effect against allogeneic lymphocytes to induce blastoid transformation. The liver cells stimulated allogeneic lymphocytes to induce blastoid transformation and to increase incorporation of 3H-thymidine, and the magnitude of the mixed lymphocyte-liver cell culture reaction in various donor recipient combinations corresponded to MLC and survival time of skin allografts.抄録全体を表示PDF形式でダウンロード (326K) -
MASAKUNI SUZUKI, YUMIKO TANEMOTO, KATSUYUKI TAKAHASHI1972 年 108 巻 1 号 p. 9-18
発行日: 1972年
公開日: 2008/11/28
ジャーナル フリーNeurohumoral factors maintaining the balance between the hypothalamus and the pituitary have been studied in recent years with reference to the effects of various chemicals. The authors studied the influence of copper salts in vivo on the hypothalamic ovulatory hormone releasing factor. Crude hypothalamic extract was injected into the pituitary and the increase of the rate of ovulation was noted, as the concentration of the extract rose. Injection of a crude hypothalamic extract, prepared in the presence of copper, into the pituitary caused a pronounced increse in the rate of ovulation. This increase was proportional to the increase in concentration in copper and was greater than that in the case of injection of simple hypothalamic extract. Ovulation in response to injection of the hypothalamic extract within one hour after intravenous injection of cupric sulfate was highest, and no ovulation occurred with the injection alone 12 hours later. These findings suggest the induction of ovulation through the action of copper on the ovulatory hormone releasing factor probably present around the median eminence of the hypothalamus.抄録全体を表示PDF形式でダウンロード (1706K) -
HISAO AOBA, KUNIO AITA, KIMIO NAKAGAWA, KATSUYUKI TAKAHASHI, MUTSUO HI ...1972 年 108 巻 1 号 p. 19-23
発行日: 1972年
公開日: 2008/11/28
ジャーナル フリーAlkaline phosphatase activity of 116 placentas derived from 12 pregnant Sprague-Dawley albino rats was determined by Manning's method in order to evaluate the alteration of enzyme activity in the abnormal pregnancy. This parameter was achieved by studying fetal death (29 cases) resulted from the ligation of the umbilical cord and utero-placental insufficiency developed by the ligation of the uterine blood vessels (34 cases). On the 18 th day of gestation surgery was performed on the rat. Placental alkaline phosphatase activity was determined at the end of 4, 8 and 12 hours after ligation. In the case of fetal death, placental alkaline phosphatase activity remained approximately 94% of the control throughout the experimental period. When the utero-placental circulation was disturbed by ligation, the enzyme activity decreased to 70.5% during the first 12 hour period. This suggests that placental alkaline phosphatase is dependent upon the intrinsic factor of maternal circulation but is less related to the state of the fetus. Therefore it seems possible that the activity of the placental alkaline phosphatase is a sensitive indicator of placental activity.抄録全体を表示PDF形式でダウンロード (855K) -
ISAKO HOMMA, YOJI ISHIYAMA, MITURU EBE1972 年 108 巻 1 号 p. 25-37
発行日: 1972年
公開日: 2008/11/28
ジャーナル フリーThe effects of Droperidol on EEGs of both cortex and hippocampus, VEP, ECG, respiration and body movement were investigated in sixteen adult albino rats. The dose administered, i. p., was graded 0.05, 0.5, 2.5, 5, 25, 50, 75 and 100mg/kg. EEGs in both cortex and hippocarnpus were stable apparently in small dose, but the regularity in cortical EEG increased according to the frequency analysis. In large dose both EEGs changed to slow rhythm superimposing fast activity and in extremely large dose they faded out. Peak latencies of the components in VEP shortened in small dose and delayed in large dose. Pulse rate increased in small dose, but decreased in large dose. Ischemic effects to ECG were found in extremely large dose. Respiratory rate was hardly affected. Body movement was calmed down. The maximum effects appeared at 15 to 60min after the medication and the effects continued for several hours, but they were well correlated with the administered dose.抄録全体を表示PDF形式でダウンロード (585K) -
MITURU EBE, ISAKO HOMMA, YOJI ISHIYAMA1972 年 108 巻 1 号 p. 39-54
発行日: 1972年
公開日: 2008/11/28
ジャーナル フリーBoth visual evoked potentials (VEP) and unit discharges by Xenon flash were recorded with macro- and micro-electrode technique from visual cortex of albino rat adapted to dark environment under very light anesthesia. Some characteristics of VEP and the relation between laminal VEP and unit discharges were investigated. 1. VEP led by ball electrode from cortical surface was individually different in configuration, but it had six wave components statistically. Averaged peak latencies of them were as follows: 1 st 26 msec, 2 nd 36 msec, 3 rd 73 msec, 4 th 91 msec, 5 th 111 msec and 6 th 182 msec in order of from positive to negative. The 4 th to 6 th components were labile in configuration. Especially, the 4 th negative wave appeared separately or was included within the 6 th wave or changed to rhythmic after-discharge in sequential series of recording in some cases. 2. As a microelectrode was inserted into cortex, the amplitude of VEP increased. Especially, the 2 nd negative wave increased in amplitude and had small ripples on it. At the depth of about 1mm in cortex some ripples showed phase reverse in some cases. The peak latencies after the 3 rd wave delayed. 3. Both spontaneous and responding discharges were most frequently observed at the depth of about 1mm, but injury discharges at the relatively superficial layer. 4. Correspondence of responding discharges for repeated stimulation to VEP was apparently complicated and not constant in unit to unit and even in the same one. However, the correlation between the unit discharges and VEP was evident on time-histogram by means of the data processing computer.抄録全体を表示PDF形式でダウンロード (1496K) -
SIGERU IKEDA, ATSUSHI KIMURA, HIROSHI SHIONO, RYOICHI KOGASAKA, TOORU ...1972 年 108 巻 1 号 p. 55-62
発行日: 1972年
公開日: 2008/11/28
ジャーナル フリーClinical and virologic studies of 2 cases with generalized herpes zoster were reported. The mechanism of varicelliform dissemination of zoster was thought to be as follows: one case was due to the immunodeficient state, but in the other case showing no abnormalities in immunoglobulins and antibody response the cause was not determined.抄録全体を表示PDF形式でダウンロード (1402K) -
TATUO SAITO, AKIRA WAKUI, JUN-ICHI KIKKAWA, TOSHIO KUDO, KUNIMI KIKUCH ...1972 年 108 巻 1 号 p. 63-77
発行日: 1972年
公開日: 2008/11/28
ジャーナル フリー1) Total lipid content in Ehrlich ascites carcinoma cells decreased gradually with considerable fluctuations in the course of cell growth. There was also remarkable fluctuation in individual lipid component. A gradual decrease in the quantity of phospholipid during tumor growth was responsible for a decrease of total lipid. 2) The main components of phospholipids in mitochondria and microsome were lecithin and phosphatidyl ethanolamine. A fairly large quantity of sphingomyelin was found in microsomal fraction. 3) In fatty acid composition of individual lipid fractions, there was a tendency for C 18:0 to be high in phospholipid. The content of C 18:0 in simple lipid of subcellular fractions from Ehrlich ascites carcinoma cells exceeded that of the corresponding subcellular fraction from other tissues. This tendency was especially remarkable in mitochondrial fraction. 4) From the results mentioned above, considerable differences in lipid metabolism between normal tissues and cancer were noted. Analysis of lipid metabolism in cancer cells may offer helpful suggestions for cancer chemotherapy.抄録全体を表示PDF形式でダウンロード (760K) -
ISAMU USUBUCHI, YUKIO SOBAJIMA, HAJIME KUDO, TOSHIRO HONGO, MICHIYOSHI ...1972 年 108 巻 1 号 p. 79-84
発行日: 1972年
公開日: 2008/11/28
ジャーナル フリーCross-immunity among mammary carcinomas of C3H/He mice and that between mammary carcinoma and methylcholanthrene (MCA)-induced sarcoma of C3H/He mice were observed. The degree of immunity in cases of spontaneous regression of the immunizing tumor was more marked than that in cases of ligation-and-release or of surgical excision of the immunizing tumor. Although antigenicity peculiar to the animal in which the tumor originated, in addition to common antigens, had been shown in allogeneic tumors, such antigenicity could not be demonstrated in syngeneic tumors. Autologous transplantation of mammary carcinomas of C3H/He mice was inhibited effectively by immunization with syngeneic MCA-induced sarcoma. The degree of inhibition was more marked in cases of spontaneous regression of the immunizing tumor than in cases of ligation-and-release or of surgical excision of the immunizing tumor.抄録全体を表示PDF形式でダウンロード (374K) -
MASARU OHTA, HIROKO HASEGAWA1972 年 108 巻 1 号 p. 85-94
発行日: 1972年
公開日: 2008/11/28
ジャーナル フリーPhospholipase A activity was investigated in rat lung homogenate using a-3H-palmitoyl lecithin, a-14C-palmitoyl-phosphatidylethanolamine and 2-3H-glycerol labeled phosphatidylethanolamine as substrates. The activity was estimated by measuring the release of radioactive products (fatty acids, water soluble compounds and lysophospholipids). It was noted that lung hydrolase accumulated more lyso-compounds in comparison with that of the liver. The hydrolysis proceeded linearly during the 6 hr incubation. The enzyme did not require Ca++ ions, and was somewhat inhibited at higher concentrations of Ca++. Sodium deoxylcholate inhibited both the release of fatty acids and lysophospholipids. Half of the total activity of the lung was found in the supernatant fraction, while the liver supernatant showed only a quarter of the total activity. The 14C/3H ratios of the lysophosphatidylethanolamine suggested that phospholipase A2 activity was higher than phospholipase A1 activity in the lung.抄録全体を表示PDF形式でダウンロード (1045K) -
SHINOBU MATSUDA, NORIYOSHI SUKENO, NAKAO ISHIDA1972 年 108 巻 1 号 p. 95-96
発行日: 1972年
公開日: 2008/11/28
ジャーナル フリーA mixed human serum containing Australia (Au) antigen was fractionated by a discontinuous sucrose gradient centrifugation. When Au antigen in each fraction was assayed by radioimmunoassay (RIA) and imniunoelectrosyneresis (IES), the peaks in titer of both assay systems appeared in different fraction. The RIA peak fraction contained spherical particles with dense core and tubular forms.抄録全体を表示PDF形式でダウンロード (110K) -
YASUO TSUKAHARA, KYOJI TASAKI1972 年 108 巻 1 号 p. 97-98
発行日: 1972年
公開日: 2008/11/28
ジャーナル フリーThe regenerative process of rhodopsin in the isolated octopus retina was studied based on observations on waveform changes of the ERP. The amplitude of the ERP of rhodopsin was decreased by intense pale yellow light and was restored during the period of dark adaptation. The dark recovery was not notable when blue light was used in place of yellow light. It was suggested that the rhodopsin regenerates in darkness from an intermediate substance which is photoconverted from acid metarhodopsin.抄録全体を表示PDF形式でダウンロード (138K) -
AKIRA TATEDA, KANEO KIKUCHI, RYOICHI SHIRACHI, TAKUSEI UMENAI, NAKAO I ...1972 年 108 巻 1 号 p. 99-100
発行日: 1972年
公開日: 2008/11/28
ジャーナル フリーSerial specimens of serum collected every week from a group of 79 patients who received blood transfusions before or after surgical operation were examined for Australia (Au) antigen and antibody. Out of 18 cases which received Au positive blood, 8 developed antigenemia and 7 produced antibody. Out of 61 cases which received Au negative blood, 21 cases showed antibody response. Out of total 79 recipients, 8 cases developed hepatitis (10%) 6 out of which were the patients who received An negative blood.抄録全体を表示PDF形式でダウンロード (129K)
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