巻号一覧
108 巻 (1972)
- 4 号 p. 307-
- 3 号 p. 199-
- 2 号 p. 101-
- 1 号 p. 1-
108 巻, 2 号
選択された号の論文の10件中1～10を表示しています
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KOZUI MIYAZAWA, MASAAKI YAMAKI, KINJI ISHIKAWA, KAI TSUIKI, YOSHINORI ...1972 年 108 巻 2 号 p. 101-111
発行日: 1972年
公開日: 2008/11/28
ジャーナル フリーAortic regurgitation was measured from the dye dilution curves recorded simultaneously from the left ventricle and femoral artery following continuous injection of dye into the aortic root. In 18 cases with aortic regurgitant murmur, regurgitant fraction ranged from 7.3 to 145.0% of aortic forward flow, and no regurgitant flow was detected in 4 control patients. Comparing the results of continuous injection method with those of rapid injection method performed in succession, there was a considerable difference of the values between both methods. Reproducibility of measurement was excellent in the continuous method (r=0.98), while poor in the rapid method (r=0.38). The defect of the latter method was primarily due to the inadequate timing of dye injection in relation to the phase of the cardiac cycle. Regurgitant fraction was correlated with diastolic valve area (r=0.78), heart rate (r=-0.46), and peripheral vascular resistance (r=-0.45). There was no close correlation between regurgitant fraction and diastolic pressure gradient from aorta to left ventricle or diastolic time. It is concluded that the continuous injection method can be used as a valid means for estimating aortic regurgitant flow in man and for evaluating hemodynamics in aortic valve disease.抄録全体を表示PDF形式でダウンロード (1302K) -
HAJIME HOSHI1972 年 108 巻 2 号 p. 113-121
発行日: 1972年
公開日: 2008/11/28
ジャーナル フリーBursectomized and X-irradiated chickens were given intraperitoneal inoculation of live bursa cells in an attempt to restore the periellipsoidal lymphoid cells in their spleens. An injection of viable cells prepared from autologous bursae into neonatally bursectomized and X-irradiated chickens produced no recognizable restoration of the bursa-dependent lymphoid elements, i.e., periellipsoidal lymphoid cells, germinal center cells and plasma cells. A slight restorative effect was found by inoculations on the 8 th and 9 th days of a large number of homologous bursa cells, which were obtained from newly hatched or 4-week-old chickens. In the chickens which were bursectomized, X-irradiated and given their own unirradiated bursa cells at around 2 weeks of age, all the bursa-dependent elements including the periellipsoidal lymphoid cells were found considerably restored. The result shown by the 2-week-old chickens was thought to provide a circumstantial support for the concept that the periellipsoidal lymphoid cells may be one of the cell lineages stemming from the bursal lymphoid cells.抄録全体を表示PDF形式でダウンロード (2499K) -
MASAKUNI SUZUKI, TAKESHI TAKAHASHI, TETSURO ABE1972 年 108 巻 2 号 p. 123-131
発行日: 1972年
公開日: 2008/11/28
ジャーナル フリーIn order to clarify the in vitro action of clomiphene, F 6066 and Lychium chinense Miller (LCM) on the pituitary, the anterior pituitary of the rat was incubated with these materials and the gonadotropin in the medium was assayed. 1) Clomiphene showed no increase of LH secretion upon its addition to the incubation medium containing the pituitary alone or in the presense of the hypothalamus. The addition of a large amount of clomiphene induced a slight increase in secretion of FSH but it was not statistically significant, while prolactin secretion was significantly stimulated by a small amount of clomiphene. Secretion of prolactin was stimulated even in the presence of the hypothalamus. 2) F 6066 acted directly on the pituitary, markedly stimulating LH secretion. No significant changes of FSH and prolactin values were observed. 3) Extracts from LCM acted directly on the pituitary to stimulate LH secretion. 4) The results described above suggest that both clomiphene and F 6066 act on the diencephalon-pituitary system. Clomiphene gives a more marked effect on prolactin, while F 6066 acts on LH secretion more strongly. The action of LCM to induce ovulation is presumably consisted of a direct action on the pituitary to induce LH secretion. Further studies are necessary to elucidate the mechanism of action of these substances.抄録全体を表示PDF形式でダウンロード (551K) -
TOYOAKI AKINO, ISAO YAMAZAKI, MASAO ABE1972 年 108 巻 2 号 p. 133-139
発行日: 1972年
公開日: 2008/11/28
ジャーナル フリーThe incorporation of labeled lysolecithin into various rat organs was studied. Lysolecithin injected was rapidly taken up by various organs and it was found that the conversion into lecithin proceeded more rapidly in the liver and intestine than in other organs. The mode of formation of lecithin from lysolecithin in various organs was also studied in vivo. Using lysolecithin doubly labeled with the glycerol and fatty acid portions, it was shown that lysolecithin injected was preferentially converted to tetraenoic lecithin in all organs examined by Lands' pathway, while the saturated+monoenoic species of the lung and brain was formed with 14C/3H of approximately 2.0 by Marrinetti's pathway. These results suggest that the lysolecithin-lecithin cycle between liver and plasma may serve to retain polyunsaturated fatty acids, and the saturated lecithin in the lung known as a surfactant may only in some parts be derived from exogenous lysolecithin.抄録全体を表示PDF形式でダウンロード (413K) -
GORO KAKIZAKI, NOBORU NOTO, YOSHIYUKI FUJIWARA, TETSUNOSUKE OIZUMI, TA ...1972 年 108 巻 2 号 p. 141-153
発行日: 1972年
公開日: 2008/11/28
ジャーナル フリーIn rats of recovery from experimentally produced pancreatitis it was found that histologic findings and amylase values of the parotid gland changed parallel to the severity of pancreatic changes and that there was no significant correlation between histologic changes of the pancreas and serum amylase values during repairing period of the pancreatitis.抄録全体を表示PDF形式でダウンロード (4924K) -
GORO KAKIZAKI, NOBORU NOTO, YOSHIYUKI FUJIWARA, TETSUNOSUKE OIZUMI, TA ...1972 年 108 巻 2 号 p. 155-164
発行日: 1972年
公開日: 2008/11/28
ジャーナル フリーHistologic examination and measurement of amylase content of the pancreas and parotid gland were done on rats with peritonitis or ileus. Histologic findings and amylase content of the parotid gland were normal when the pancreas remained histologically normal in these conditions; while pathologic changes and low amylase content of the parotid gland were brought about when histopathologic findings of the pancreas was induced by peritonitis or ileus experimentally produced. There was no significant relation between serum amylase levels and the grade of histopathologic changes of the pancreas in rats with peritonitis or ileus.抄録全体を表示PDF形式でダウンロード (2846K) -
GORO KAKIZAKI, NOBORU NOTO, YOSHIYUKI FUJIWARA, EIICHI KATO, TAKUZO IS ...1972 年 108 巻 2 号 p. 165-177
発行日: 1972年
公開日: 2008/11/28
ジャーナル フリーDegenerative changes of the parotid gland and a marked decrease of the maximum bicarbonate concentration in parotid saliva were found in dogs with acute experimental pancreatitis.抄録全体を表示PDF形式でダウンロード (3867K) -
MANABU KAGAYAMA, AKINORI NISHIYAMA1972 年 108 巻 2 号 p. 179-193
発行日: 1972年
公開日: 2008/11/28
ジャーナル フリーThe innervation of the submandibular glands of cat and rabbit was studied by electron microscopy. The acini of the submandibular glands of both species were composed of myoepithelial cells and two types of secretory cell; namely, acinar and demilunar cells in the cat, and neck and acinar cells in the rabbit. In the peri-acinar connective tissue there were both adrenergic and cholinergic nerve endings which were differentiated by their contents of synaptic vesicles, especially of small granular vesicles. These nerve endings were surrounded partly or completely by Schwann. cell cytoplasm. On the other hand, only one type of nerve ending (cholinergic) was observed within the acini. These intra-acinar nerve endings were devoid of Schwann cell sheath, contacted directly with the plasma membranes of the myoepithelial cells and of the one type of secretory cell that was close to the intercalated duct; namely, the acinar cells in the cat and the neck cells in the rabbit. The occurrence of the nerve endings within the acini was seen more frequently in young cats but somewhat less in adult cats. The functional significance of the intra-acinar nerve endings is discussed.抄録全体を表示PDF形式でダウンロード (5605K) -
TOSHIYUKI OZAKI, SECHIKO SASAKI1972 年 108 巻 2 号 p. 195-196
発行日: 1972年
公開日: 2008/11/28
ジャーナル フリーThe slow potential (SP) changes elicited in the cerebrum by rhythmic flash stimulation were led from the scalp above the rabbit visual cortex in awaked resting state. The time course of SP changes caused by rhythmic flash stimulation was traced at the same time as the summated average responses of evoked EEG responses, that is, visually evoked responses (VERs). The negative shifts of the cerebral SP changes were observed to be augmented. gradually, as the counts of stimulation increased. In the VERs, the same tendency was recognized as the time course of the negative shifts of the cerebral SP. The relationship between the negative shifts of the cerebral SP changes and VERs was discussed.抄録全体を表示PDF形式でダウンロード (122K) -
KEIYA TADA, TSUTOMU UESAKI, GEN ISSHIKI, TOSHIAKI OURA1972 年 108 巻 2 号 p. 197-198
発行日: 1972年
公開日: 2008/11/28
ジャーナル フリーIt has been reported that the serum level of uric acid is elevated in Down's syndrome. The present study was undertaken to investigate whether the regulation mechanism of uric acid biosynthesis by hypoxanthine-guanine phosphoribosyltransferase (HGPRT) and adenine phosphoribosyltransferase (APRT) is impaired in Down's syndrome. The activities of HGPRT and APRT in erythrocytes were determined in 14 cases of Down's syndrome and 10 cases of healthy children. There was no significant difference in activities of both enzymes between Down's syndrome and controls. These findings indicate that the activity of HGPRT or APRT may not be controlled by chromosome 21.抄録全体を表示PDF形式でダウンロード (99K)
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