巻号一覧
53 巻 (1950 - 1951)
- 3-4 号 p. 207-
- 1-2 号 p. 1-
53 巻, 3-4 号
選択された号の論文の25件中1～25を表示しています
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浦山 晃1951 年 53 巻 3-4 号 p. 207-215
発行日: 1951/03/25
公開日: 2008/11/28
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CXXXIV. Mucosin. First Report石川 忠一1951 年 53 巻 3-4 号 p. 217-222
発行日: 1951/03/25
公開日: 2008/11/28
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III. On Ascitic Fluid. Third Report千葉 博, 高久 功, 佐藤 與一1951 年 53 巻 3-4 号 p. 223-236
発行日: 1951/03/25
公開日: 2008/11/28
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CXXXV. Paper Partition Chromatograms of Sugar Components in Glucidamins and Glycoproteins. II正宗 一, 吉澤 善作, 眞本 正博1951 年 53 巻 3-4 号 p. 237-241
発行日: 1951/03/25
公開日: 2008/11/28
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早川 光久1951 年 53 巻 3-4 号 p. 243-249
発行日: 1951/03/25
公開日: 2008/11/28
ジャーナル フリー1. In human gastric mucosa besides peptic action, are found cathepsin action (pH 4.0-5.0, casein, egg albumin and serum albumin ) and catheptic _??_ pepton splitting action (cathopeptonase). And casein is also at pH 8.5 hydrolized (72 hrs.).
2. I have succeeded also with human gastric mucosa to separate the pepsin action from the cathepsin action, and also the cathopeptonase action from the erepsin action by means of acid and alkaline treatment respectively according to the methods of Utzino and Sakai.3)
3. In human gastric mucosa halogen-acylase action (pH 7.8, chlor-acetyl-1-leucin and chloracetyl-1-phenylalanin) is found, but carboxy-peptidase action (pH 7.8, benzoyl-diglycin, with kinase) or hippuricase action (pH 7.8, benzoyl-glycin) not. The hydrolysis of chlor-acetyl- _??_ diglycin at pH 7.8 by gastric mucosa from ulcer stomach is certain extent recognized.
4. Neither acid carboxy-peptidase action nor. acid acyldipeptidase action (pH 4.2-4.6, benzoyl-diglycin, chloracetyl-diglycin) despite of the cystein activation is still yet found. The hydrolysis of diglycin, chlor-acetyl-l-leucin, chloracetyl-phenylalnin and benzoyl-glycin at pH 4.5 with cystein, all of these are negative.抄録全体を表示PDF形式でダウンロード (314K) -
II. Its Tryptase Activity早川 光久1951 年 53 巻 3-4 号 p. 251-258
発行日: 1951/03/25
公開日: 2008/11/28
ジャーナル フリー1. In human gastric mucosa tryptase activity (pH 7.2-8.4, casein & gelatin) is surely present, but against it serum albumin and egg albumin are usually resistent.
2. Tryptase of human gastric mucosa may partially find itself in desmo-form and its activity remains also in the presence of not dialyzed serum albumin or egg albumin unaffected. The hydrolysis of gelatin seems to undergo some retardation in the presence of human serum but that ofcasein surely not. The tryptase activity is rather inhibited by cystein, but no effect of kinase activation is found.
3. Tryptase activity of human gastric mucosa undergoes activation in the presence of dialyzed albumin, with which such a protein as egg albumin or serum albumin comes to be hydrolyzed, though it is usually resistent to the tryptase activity.抄録全体を表示PDF形式でダウンロード (345K) -
First Report. Inhibition Mechanism of Serum against Tryptic Proteolysis早川 光久1951 年 53 巻 3-4 号 p. 259-267
発行日: 1951/03/25
公開日: 2008/11/28
ジャーナル フリーThrough my experiments no difference could be noticed between serum and serum albumin with regard to their inhibition mechanism.
1. No difference can be observed between serum and serum albumin with regard to their inhibition mechanism against proteolysis.
2. Goldstein's theory3) is applicable to the substrate-trypsin-serum system, too.
3. In the inhibition of serum against tryptic proteolysis the reversible compound is formed, according to the law of mass action, between enzyme and inhibitor in serum.
4. I have built an equation representing these relations.抄録全体を表示PDF形式でダウンロード (404K) -
Second Report. A New Clinical Method by Formal-Titration of Measuring Antitryptic Index of Serum早川 光久1951 年 53 巻 3-4 号 p. 269-273
発行日: 1951/03/25
公開日: 2008/11/28
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Third Report. Chemical Nature of Antitryptic Activity of Serum. I. Its Relation to Serum Protein早川 光久1951 年 53 巻 3-4 号 p. 275-281
発行日: 1951/03/25
公開日: 2008/11/28
ジャーナル フリー1. Tryptase activity in serum (pH 7.8, hydrolysis of casein). is generally inhibited by serum itself and is not to be recognized directly.
2. The inhibitory action against pancreas trypsin can be demonstrated not only in albumin fraction but also in globulin fraction of serum.
3. The smaller the pH value (under pH 4.2) employed for the acid treatment is, the more evident is it that the antitryptic activity of serum after the treatment disappears in proportion to the degree of degeneration of serum protein. The appearance of serum tryptase activity is distinct after the treatment rather at more than pH 4.8.
4. After the adsorption with kaolin at nearly isoelectric point of a serum protein, antitryptic activity of serum disappears not proportionally to the decrease in N-amount of the serum.抄録全体を表示PDF形式でダウンロード (334K) -
Fourth Report. Chemical Nature of Antitryptic Activity of Serum. II. Its Symplextheory早川 光久1951 年 53 巻 3-4 号 p. 283-289
発行日: 1951/03/25
公開日: 2008/11/28
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Fifth Report. Serum Antitryptic Index of the Patients with Castric or Duodenal Ulcer and with Gastric Cancer早川 光久1951 年 53 巻 3-4 号 p. 291-301
発行日: 1951/03/25
公開日: 2008/11/28
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早川 光久1951 年 53 巻 3-4 号 p. 303-307
発行日: 1951/03/25
公開日: 2008/11/28
ジャーナル フリー1. The hydrolysis of casein at pH 4.5-5.0 by gastric mucosa of a rabbit is activated apparently in the presence of serum or plasma, while that of pepton and also that of casein or serum albumin at pH near 2.0 always remain unaffected.
2. The hydrolysis of casein at pH 4.5 by rabbit liver is inhibited by serum but that of pepton at pH 4.5 or 7.8 is not. These two pepton splitting activities can be separated from each other by alkaline or acid treatment.
3. The hydrolysis of casein and serum albumin at pH 4.4-5.0 by gastric mucosa (human) are to some extent inhibited by serum or scarecely undergo influence, while that of egg albumin is activated by serum. The hydrolysis of pepton at pH 4.6 and that of casein or serum albumin at pH 2.0, all remain without being influenced.
4. Catheptic pepton splitting enzyme action (cathopeptonase) may presumably be in a rabbit's liver, in its gastric mucosa and also in human gastric mucosa.抄録全体を表示PDF形式でダウンロード (225K) -
早川 光久1951 年 53 巻 3-4 号 p. 309-316
発行日: 1951/03/25
公開日: 2008/11/28
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佐藤 久夫1951 年 53 巻 3-4 号 p. 317-324
発行日: 1951/03/25
公開日: 2008/11/28
ジャーナル フリー1) The cardiac rhythms of dogs, the respiratory arrhythmias in particular, were studied by “Cardiotachograph” in experimentally induced hyper- and hypo-thyroidism.
2) In hyperthyroidism, besides tachycardias, marked decrease and finally complete disappearance of respiratory arrhythmias were noticed These can be looked upon as characteristics in hyperthyroidism.
3) In hypothyroidism, on the contrary, bradycardias were accom-panied by exaggerated respiratory arrhythmias.
4) There was noticed a distinct correlation between the respiratory arrhythmias and pulse rates throughout the experimental conditions.
5) These changes in respiratory arrhythmia were found to be due mainly to changes in the expiratory pulse intervals, the inspiratory pulse intervals, on the other hand, being modified but little.抄録全体を表示PDF形式でダウンロード (2754K) -
佐藤 久夫1951 年 53 巻 3-4 号 p. 325-330
発行日: 1951/03/25
公開日: 2008/11/28
ジャーナル フリー1. The pattern of cardiac rhythm of man as observed by means of cardiotachograph, is to some extent, a characteristic to each individual.
2. By repeated and careful observations on twenty normal individuals there were recognized three main components of cardiac rhythm which characterized its pattern. That is 1) the respiratory arrhythmias, 2) the slow waves and 3) the irregular waves.
3. The features of these three components except the respiratory arrhythmias were described and discussed.抄録全体を表示PDF形式でダウンロード (3355K) -
佐藤 彰1951 年 53 巻 3-4 号 p. 331-332
発行日: 1951/03/25
公開日: 2008/11/28
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First Report松田 順皓1951 年 53 巻 3-4 号 p. 333-339
発行日: 1951/03/25
公開日: 2008/11/28
ジャーナル フリー1. From human liver group active lipoids were separated. Of them A and B group substance inhibited isoagglutination of erythrocytes at a dilution from 1:1600_??_3200 specifically.
2. These group lipoids dissolved in water, benzene, chloroform, tetralin and glacial acetic acid, but not in ethanol, ether, petroleum ether and -acetone. They dissolved in methanol scarcely in the cold but to a certain extent when boiled.
3. The group lipoids contained galactose, hexosamine, P and N in equivalent proportions of roughly 1:1(most probably): 10:10. Their minimum molecular weight (The substances were presumed as nearly pure) of 6500 was computed out from galactose content. N. E., 600_??_700.抄録全体を表示PDF形式でダウンロード (369K) -
本川 弘一, 岩間 吉也1951 年 53 巻 3-4 号 p. 341-349
発行日: 1951/03/25
公開日: 2008/11/28
ジャーナル フリーThe change in electrical excitability of excised frog eyes was investigated with action potentials of optic nerves as the index of excitation.
1. The excitability-time curve or excitability curve after an illumination by white light shows three humps at about 1.5, 3, and, 5 minutes after, the end of the illumination at room temperature of 15-20°C. These humps are called R, G and B elevations.
2. When colored light is used instead of white light for pre-illumination the three elevations appear in different proportions according to the wave-length of the light. Predominant elevations of curves obtained by pre-illumination with red, green and blue lights are R, G and B respectively.
3. Percentage increases of electrical excitability above its resting level are denoted by ζ. Between the maximum ζ and the logarithm of the intensity of pre-illuminating light a linear relation holds in a wide range of intensities.
4. The excitability curve for white light is markedly deformed when the eye is continuously exposed to weak colored light after removal of the pre-illuminating white light. This phenomenon is due to an inhibitory effect exerted by the continuous light upon color processes. Red, green and blue lights have a selective inhibitory action upon the R, G and B processes respectively.
5. When pre-illuminating white light is preceded by any colored light, an excitability curve is obtained which is similar to that obtained when the eye is illuminated by the complementary color alone. For example, in this respect white light preceded by blue light is equivalent to yellow light. This is evidently a physiological phenomenon underlying successive color contrast.抄録全体を表示PDF形式でダウンロード (429K) -
A Contribution to the Study of Argyrophil Fibers石垣 義一郎, 黒羽 武1951 年 53 巻 3-4 号 p. 351-358
発行日: 1951/03/25
公開日: 2008/11/28
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鈴木 泰三1951 年 53 巻 3-4 号 p. 359-365
発行日: 1951/03/25
公開日: 2008/11/28
ジャーナル フリー(1) It was confirmed that the successive injection of cobalt into rabbits day after day brings about a definite increase of reticulocyte, followed by an increase of erythrocyte and hemoglobin content, There is no change in leukocyte count.
(2) There was observed a little difference in degree but not in nature between the polycythemia producing effects of the intravenous and subcutaneous injections.
(3) The injection of a large dose of cobalt salt at a time did not bring about an increase in erythrocyte count. Only successive, daily in-jections brought about the effect.
(4) Splanchnic nerve plays no part in the cobalt polycythemia.
(5) There was no difference in oxygen carrying capacity between . the hemoglobin of normal and polycythemic blood.抄録全体を表示PDF形式でダウンロード (332K) -
鈴木 泰三1951 年 53 巻 3-4 号 p. 367-371
発行日: 1951/03/25
公開日: 2008/11/28
ジャーナル フリーThe hematopoietic actions offour complex salts of cobalt were examined on rabbits. Purpureo salt did not bring about any significant altering in blood findings but other three salts, that is, Carbonatotetrammine cobaltic nitrate, Flavo salt and Croceo salt, produced polycythemias. Among these complex salts which revealed itself to be effective, there were noticed a certain differences in its effects quantitatively as well as qualitatively.
The auther takes pleasure in expressing his sincere thanks to Prof. K. Matsuda for his advice and interest throughout the work. The costs of this work were defrayed by a grant offered to him from the Foundation for Promotion of Scientific Research of the Education Department.抄録全体を表示PDF形式でダウンロード (187K) -
Second Report松田 順皓1951 年 53 巻 3-4 号 p. 373-382
発行日: 1951/03/25
公開日: 2008/11/28
ジャーナル フリーA preparation of Group A lipoid of human liver was hydrolyzed and fractioned. Separated were glucosamine (as hydrochloride), galactose (as methylphenylhydrazone), choline (as chioroplatinate), palmitic acid, an unsaturated hydroxyacid, a probable keto-alcohol and three substances containing N and P. Moreover qualitative tests suggested the presence of formic acid, tyrosine, xanthine and hypoxanthine or guanine among the cleavage products. Sphingosine, glycerol, glycerophosphoric acid and acetic acid were absent.
A short discussion was made regarding the results.抄録全体を表示PDF形式でダウンロード (661K) -
CXXXVI. A Hexosamine-containing Carbohydrate and a Glucidamin from Human Liver松田 順皓1951 年 53 巻 3-4 号 p. 383-388
発行日: 1951/03/25
公開日: 2008/11/28
ジャーナル フリーFrom normal human liver two hexosamine-involving substances, one a carbohydrate and the other a glucidamin, were separated. The carbo-hydrate was blood-group (ABO system)-active and the glucidamin inert in this respect. Their composition was discussed.抄録全体を表示PDF形式でダウンロード (338K) -
田村 正男1951 年 53 巻 3-4 号 p. 389-398
発行日: 1951/03/25
公開日: 2008/11/28
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本川 弘一, 岩間 吉也, 塚原 進1951 年 53 巻 3-4 号 p. 399-406
発行日: 1951/03/25
公開日: 2008/11/28
ジャーナル フリーColor processes at single retinal elements or at a restricted number of elements of Japanese toads were investigated with the aid of microelectrodes, taking well-isolated spikes as the index. The electrical excitability of a single retinal element as a function of time after cessation of pre-illuminating white light shows a maximum at 1.5, 3 or 5 minutes. These values of crest time correspond respectively to those of the R, G and B elevations which are found on the excitability curve for white light determined with action potentials of the whole optic nerve as the index. From retinal elements responding with isolated spikes to optic and electric stimuli sometimes an excitability curve having two distinct humps was obtained.
A histogram concerning crest times of excitability curves of these isolated elements shows that there are three groups of retinal elements. The number of elements belonging to each group was 23 for the R group, 21 for the G group and 21 for the B group. When red light was used instead of white light for pre-illumination all the 19 elements tested in this series of experiments showed excitability curves of the R type. The retinal elements so far studied are to be identified with Granit's modulators.抄録全体を表示PDF形式でダウンロード (1206K)
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