巻号一覧
46 巻 (1972)
- 6 号 p. 283-
- 5 号 p. 219-
- 4 号 p. 151-
- 3 号 p. 85-
- 1-2 号 p. 1-
46 巻, 1-2 号
選択された号の論文の26件中1～26を表示しています
- |<
- <
- 1
- >
- >|
-
月田 潔原稿種別: 本文
1972 年 46 巻 1-2 号 p. 1-18
発行日: 1972/08/25
公開日: 2018/02/27
ジャーナル フリーHistorical sketch and general considerations on NMR : analysis of fatsoluble vitamins are briefly reviewed. Several potential techniques for obtaining NMR data amenable to first-order analysis are described and special emphasis is given to the application of a paramagnetic shift reagent Eu(DPM)_3 in this field. Extensive data are accumulated with typical illustrations and future extension is prospected. (Received June 10,1972)抄録全体を表示PDF形式でダウンロード (1138K) -
白井 和雄, 湯山 駿介, 上野 誠原稿種別: 本文
1972 年 46 巻 1-2 号 p. 19-24
発行日: 1972/08/25
公開日: 2018/02/27
ジャーナル フリーVitamin D_2 tetra acetyl glucoside, was synthesized from D_2 and tetra acetyl glucosyl bromide by Koenigs-Knorr reaction. The chemical structure of the compound was ascertained from its elementary analysis. UV-, IR-, mass- or NMR-spectral analysis and reacetylation after deacetylation. Neither isomerization nor rearrangement in the process of synthetic treatment was observed. Further data on the solubility in ethanol and specific rotation were determined. Although water-solubilization of D_2 was the aim of this synthetic experiment, the D_2 glucoside was insoluble in water. (Received March 24,1972)抄録全体を表示PDF形式でダウンロード (621K) -
渡辺(久芳) 君子原稿種別: 本文
1972 年 46 巻 1-2 号 p. 25-32
発行日: 1972/08/25
公開日: 2018/02/27
ジャーナル フリーA 4-methyl-5-β-hydroxyethylthiazole (Th) -requiring mutant strain of Escherichia coli 26-43,responded to either free Th or Th monophosphate in the growth medium of Davis and Mingioli. However, the amount of Th monophosphate required for a half-maximal growth of the mutant was observed to be approximately 30 times greater than that of Th. Additional experiments revealed that the mutant cells cleaved Th monophosphate into free Th and inorganic phosphate. The enzyme responsible for the conversion from Th phosphate to free Th was extracted from acetone powder of the cells and was identified as nonspecific acid phosphatase. It was suggested that Th monophosphate was hydrolyzed into Th at the surface of the cell membrane and utilized by the organism. (Received March 30,1972)抄録全体を表示PDF形式でダウンロード (841K) -
三宅 俊雄, 鈴木 幸雄原稿種別: 本文
1972 年 46 巻 1-2 号 p. 33-36
発行日: 1972/08/25
公開日: 2018/02/27
ジャーナル フリーIt was found that rutin glucoside was formed in the incubation mixture containing maltose, rutin and a partially purified enzyme preparation from Mucor javanicus having the 5'-D-riboflavin-α-D-glucopyranoside-forming activity. (Received March 31,1972)抄録全体を表示PDF形式でダウンロード (431K) -
沖中 靖, 梅沢 真樹子, 外林 秀紀, 岩井 和夫原稿種別: 本文
1972 年 46 巻 1-2 号 p. 37-44
発行日: 1972/08/25
公開日: 2018/02/27
ジャーナル フリーIn rats, fed a folic acid-deficient synthetic diet containing sulfaguanidine, growth was retarded, and decreases in the red cell count and granulocyte count and a relative increase of hypersegmented neutrophils were noted. The administration of methotrexate (2 μg per day per rat, intramuscularly) for 3 days beginning on the 18th day of the experimental diet exaggerated these hematological changes. A single injection of tetrahydrofolic acid, 5-methyl-tetrahydrofolic acid or 5.10-methenyltetrahydrofolic acid (500lμg per rat) on the 21th day of the experiment resulted in increases in the red cell count and the granulocyte count, also in the normalization of distribution of nuclear segments in neutrophils on the 2nd day. Of all the compounds tested, tetrahydrofolic acid had the most potent effect. (Received April 22,1972)抄録全体を表示PDF形式でダウンロード (646K) -
松尾 治之, 八島 啓輔, 奥田 邦雄原稿種別: 本文
1972 年 46 巻 1-2 号 p. 45-49
発行日: 1972/08/25
公開日: 2018/02/27
ジャーナル フリーThe effect of acute ethanol intoxication on the intestinal absorption of B_<12> was studied in the rat. Diluted ethanol was given by a stomach tube in a single dose of 1.8ml per 100 gram body weight and ^<57>Co-B_<12>(cyanocobalamin) was given 4 hours later. The controls received an isocaloric glucose solution. It was found that the descent of the dose from the stomach was markedly delayed in the ethanol group, necessitating a direct, transserosal instillation of ^<57>Co-B_<12> in the small intestine. Physiological doses of ^<57>Co-B_<12> with or without rat intrinsic factor concentrate, as well as a supraphysiological dose were given into the midportion of the small intestine and absorption was measured from the radioactivity recovered in the intestine and organs. It was shown that IF-mediated absorption of B_<12> was markedly impaired in the ethanol treated rats. The mucosal absorption of IF-B_<12> measured by washing the lumen shortly after administration was also impaired, but to a lesser extent than that of the reduction in overall absorption. Non-IF mediated absorption of ^<57>Co-B_<12> Was not affected under these conditions regardless of the dose, neither was the tissue uptake following parenteral administration of ^<57>Co-B_<12> altered. It was concluded that ethanol impairs the active trasnport system for B12 involving the IF mechanism. (Received April 22,1972)抄録全体を表示PDF形式でダウンロード (557K) -
中野 厚子, 前島 晴子, 宮本 悌次郎, 村田 希久原稿種別: 本文
1972 年 46 巻 1-2 号 p. 51-57
発行日: 1972/08/25
公開日: 2018/02/27
ジャーナル フリーThe thiamine requiring strain of E. coli 70-23 showed a maximum growth in the Davis' culture medium with 10^<-10〜-11> mole/tube (final concentration of 2 x 10^<-8〜-9>M) of thiamine, but did not respond well in the medium containing both of pyrimidine and thiazole moieties of thiamine. However, in the existence of 2 x 10^<-5>M pyrimidinyl-nicotinic acid(Pm-NiA)or heteropyrithaimine (HPT), and of 2 x 10^<-4>M pyrimidinyl-cysteine (Pm-CySH) or its sulfoxide (Pm-CySH→O), the bacteria responded well. Pyrithiamine showed an antithiamine activity for growth of the bacteria at the concentration of 2 x 10^<-3>M, but was utilized by the bacteria at 2 x 10^<-4>M. The antithiamine activity was eliminated after preincubation for 48 hours or addition of 2 x 10^<-3〜-7>M thiamine. The existence of thiamine in the harvested bacteria grown in the Davis' culture medium with 2 x 10^<-5>M Pm-NiA was observed by thin layer chromato-graphy. The amount of thiamine was estimated by the microbiological assay with L. fermenti as 0.27 μg/g wet bacteria, which was around 10^<-3> times of concentration to the amount of thiamine in bacteria cultured in medium with 2 x 10^<-5>M thiamine. The mechanism of changes of the thiamine related compounds in the medium into thiamine by the bacteria during cultivation was discussed. (Received May 6,1972)抄録全体を表示PDF形式でダウンロード (611K) -
小沢 樹雄, 佐野 満昭, 富田 勲原稿種別: 本文
1972 年 46 巻 1-2 号 p. 59-63
発行日: 1972/08/25
公開日: 2018/02/27
ジャーナル フリーSeveral pyridoxol analogues modified at 3 or 5 position of the pyridine ring have been synthesized. 2-Methyl-3-amin0-4,5-dihydroxymethyl pyridine (3-amino POL) which has the substituent of NH_2 at 3 position of pyridoxol, inhibited strongly the growth of S. carlsbergensis 4228 (ATCC 9080) and the inhibition was reversed by the addition of pyridoxol. The 50% inhibition index of 3-amino POL was 35 while that of 4-deoxypyridoxol was 80〜90. (Received May 19,1972)抄録全体を表示PDF形式でダウンロード (450K) -
川崎 近太郎原稿種別: 本文
1972 年 46 巻 1-2 号 p. 64-
発行日: 1972/08/25
公開日: 2018/02/27
ジャーナル フリーPDF形式でダウンロード (138K) -
藤井 高明原稿種別: 本文
1972 年 46 巻 1-2 号 p. 65-70
発行日: 1972/08/25
公開日: 2018/02/27
ジャーナル フリーThe clinical effects of vitamin E were investigated in 7 cases (3 adolescents and 4 adults) of purpura due to vascular defects caused bv infection, drugs or unknown etiologies. In this study, marked clinical improvements following the oral administration of vitamin E (400 to 600mg of α-tocopherol nicotinate per day) were observed in all cases. Six out of 7 cases showed remarkable improvements of petechiae following the vitamin E therapy alone. Complete disappearance of petechiae was observed following the administration of vitamin E for 5 days in 2 cases, 14 days in 4 cases and 21 days in 1 dase, along with the improvements of other clinical sym ptoms . (Receiaed May 24,1972)抄録全体を表示PDF形式でダウンロード (1180K) -
A.K. Chatterjee, B.B. Ghosh原稿種別: 本文
1972 年 46 巻 1-2 号 p. 71-
発行日: 1972/08/25
公開日: 2018/02/27
ジャーナル フリーPDF形式でダウンロード (157K) -
小林 正, 康村 満枝原稿種別: 本文
1972 年 46 巻 1-2 号 p. 71-72
発行日: 1972/08/25
公開日: 2018/02/27
ジャーナル フリーPDF形式でダウンロード (303K) -
藤井 高明, 清水 宏, 枝 伊佐子原稿種別: 本文
1972 年 46 巻 1-2 号 p. 72-
発行日: 1972/08/25
公開日: 2018/02/27
ジャーナル フリーPDF形式でダウンロード (195K) -
森内 幸子, 高瀬 幸子, 大泉 久美子, 細谷 憲政原稿種別: 本文
1972 年 46 巻 1-2 号 p. 72-73
発行日: 1972/08/25
公開日: 2018/02/27
ジャーナル フリーPDF形式でダウンロード (328K) -
駒井 亨, 南部 公彦, 進藤 英世原稿種別: 本文
1972 年 46 巻 1-2 号 p. 73-
発行日: 1972/08/25
公開日: 2018/02/27
ジャーナル フリーPDF形式でダウンロード (181K) -
古野 厚次, 鈴置 二郎原稿種別: 本文
1972 年 46 巻 1-2 号 p. 73-
発行日: 1972/08/25
公開日: 2018/02/27
ジャーナル フリーPDF形式でダウンロード (181K) -
北原 覚雄原稿種別: 本文
1972 年 46 巻 1-2 号 p. 75-
発行日: 1972/08/25
公開日: 2018/02/27
ジャーナル フリーPDF形式でダウンロード (171K) -
村田 希久, 田中 玲子原稿種別: 本文
1972 年 46 巻 1-2 号 p. 75-76
発行日: 1972/08/25
公開日: 2018/03/14
ジャーナル フリーPDF形式でダウンロード (320K) -
峰下 銕雄原稿種別: 本文
1972 年 46 巻 1-2 号 p. 76-77
発行日: 1972/08/25
公開日: 2018/03/14
ジャーナル フリーPDF形式でダウンロード (341K) -
藤原 元典, 糸川 嘉則原稿種別: 本文
1972 年 46 巻 1-2 号 p. 77-
発行日: 1972/08/25
公開日: 2018/03/14
ジャーナル フリーPDF形式でダウンロード (196K) -
勝沼 信彦, 真田 幸弘, 木南 英紀, 小林 圭子, 板野 喜子原稿種別: 本文
1972 年 46 巻 1-2 号 p. 77-78
発行日: 1972/08/25
公開日: 2018/03/14
ジャーナル フリーPDF形式でダウンロード (334K) -
牧野 堅, 村上 安子原稿種別: 本文
1972 年 46 巻 1-2 号 p. 78-79
発行日: 1972/08/25
公開日: 2018/03/14
ジャーナル フリーPDF形式でダウンロード (330K) -
岩井 和夫, 池田 雅充原稿種別: 本文
1972 年 46 巻 1-2 号 p. 79-80
発行日: 1972/08/25
公開日: 2018/03/14
ジャーナル フリーPDF形式でダウンロード (344K) -
内野 治人, 田中 信夫原稿種別: 本文
1972 年 46 巻 1-2 号 p. 80-
発行日: 1972/08/25
公開日: 2018/03/14
ジャーナル フリーPDF形式でダウンロード (206K) -
福井 三郎, 上原 悌次郎, 山城 敬一, 西原 浩, 谷 喜雄, 大隅 正子原稿種別: 本文
1972 年 46 巻 1-2 号 p. 80-81
発行日: 1972/08/25
公開日: 2018/03/14
ジャーナル フリーPDF形式でダウンロード (337K) -
田村 善蔵原稿種別: 本文
1972 年 46 巻 1-2 号 p. 81-
発行日: 1972/08/25
公開日: 2018/03/14
ジャーナル フリーPDF形式でダウンロード (184K)
- |<
- <
- 1
- >
- >|