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67 巻, 12 号
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Age matched control 及び multiple dose specific mitogen を用いての検討西村 泰司, William G. Guerriero, Ellen Richie1976 年 67 巻 12 号 p. 1013-1017
発行日: 1976/12/20
公開日: 2010/07/23
ジャーナル フリーCell mediated immunocompetence in 20 patients with bladder cancer(transitional cell carcinoma) and 21 healthy donors as age matched control was studied by in vitro lymphocyte stimulation to PHA and ConA, and simultaneously lymphocyte subpopulation was studied.
To avoid artifact from anesthesia, radiotherapy, cytotoxic drugs and immunological senescence in elderly patients all of which may lower lymphocyte reactivity, blood samples from patients were obtained before any treatment and usually blood from an age matched control such as a spouse or normal volunteer was simultaneously tested.
Since the optimal concentration of mitogen for lymphocyte stimulation may vary among individuals, a wide range of mitogen concentration was always used and peak response at the optimal dose was used for the evaluation.
As a result following conclusions were obtained although more patients should be evaluated, particularly these in advanced stage.
The majority of stage A patients without evidence of recurrence showed normal lymphocyte responsiveness to mitogens. Stage A patients who had recurrence within one year showed a consistently diminished lymphocyte reactivity in vitro.
Patients with diffuse carcinoma in situ were not always associated with poor lymphocyte reactivity.
Patients with more advanced disease tended to have a reduced T lymphocyte reactivity in vitro which did not correlate with the relative proportion of circulating T-cell.抄録全体を表示PDF形式でダウンロード (443K) -
日本人副腎静脈系解剖と副腎静脈カテーテル法への応用日台 英雄1976 年 67 巻 12 号 p. 1018-1024
発行日: 1976/12/20
公開日: 2010/07/23
ジャーナル フリーDissection study on adrenal and juxta-adrenal veins in 51 adult Japanese cadavors disclosed the following findings:
1) Variations in adrenal venous system in Japanese were not so frequent as in that of Euro-Americans'.
2) The right adrenal veins were located at 34.5mm below the hepatic veins and 49mm above the right renal veins and bifurcated from the vena cava at an angle of 102° with 2.8mm diameter, on the average.
3) The left adrenal veins were located at 28mm from the origin of the left renal veins and bifurcated at an angle of 130° with 3.7mm diameter, on the average.
4) Based on difference of the venous diameters, left adrenal venous blood flow was estimated as 2.3 times more than that of the right adrenal vein.
5) Occasional failure of right adrenal vein catheterization and blood sampling were attributed to anatomical relationship of the right adrenal veins and their low bloodflow.
6) Based on the anatomical study of the adrenal veins, discussions were made on the shape of the catheters and technique of adrenal vein catheterization.抄録全体を表示PDF形式でダウンロード (1965K) -
高崎 悦司, 島野 栄一郎, 永田 正義1976 年 67 巻 12 号 p. 1025-1032
発行日: 1976/12/20
公開日: 2010/07/23
ジャーナル フリー445 cases with upper urinary tract calculi, which were removed by various routes, were studied as to sizes (lengths and widths) of their stones and also as to weights for 304 cases in this series. The mean±S.D. of lengths and widths, and mean weights, of calculi were as follows: 0.6±0.3cm and 0.4±0.2cm in 149 cases, and 0.1gm in 95 cases, for spontaneously discharged calculi (Table 1-3); 0.6±0.2cm and 0.4±0.1cm in 13 cases, and 0.1gm in 11 cases, for calculi by basket catheter extraction (Table 4-6); 1.1±0.5cm and 0.7±0.3cm in 189 cases, and 0.3gm in 145 cases, with ureterolithotomies (Table 7-9); 1.7±0.9cm and 1.3±0.7cm in 51 cases, and 1.3gm in 31 cases, with pyelolithotomies (Table 10-12); 2.8±1.6cm and 1.8±1.0cm in 43 cases, and 5.7gm in 22 cases, with nephrolithotomies, partial nephrectomies and nephrectomies (Table 13-20). It is suggested that the calculi smaller than 1.2cm in length and 0.7cm in width are possible to be discharged spontaneously, and the calculi smaller than 2.1cm in length and 1.2cm in width are to be expeled into the ureter from the renal pelvis.抄録全体を表示PDF形式でダウンロード (929K) -
第4報 その遠隔成績よりみた適応因子の再解析広瀬 欽次郎, 今尾 貞夫, 赤座 英之, 塩川 英二, 瀬戸 輝一1976 年 67 巻 12 号 p. 1033-1036
発行日: 1976/12/20
公開日: 2010/07/23
ジャーナル フリーIn 60 cases of bladder cancer treated with hydrostatic pressure technique, their prognosis was evaluated in relation of initial effects after the first procedure. Groups with dramatic or favorable effects showed satisfied prognosis, which might be parallel to the degree of initial effects after hydrostatic pressure tratment. With further accumulation of pertinent cases, analysis of the 5 year survival rate would be necessary.抄録全体を表示PDF形式でダウンロード (534K) -
岸 洋一1976 年 67 巻 12 号 p. 1037-1048
発行日: 1976/12/20
公開日: 2010/07/23
ジャーナル フリーBacterial strains, isolated from the urinary tract infections in the urological department of the Tokyo University Hospital, were composed of 475 (85.6%) strains of gram negative bacilli and 80 (14.4%) strains of gram positive cocci. Among gram negative bacilli 8 (1.7%) strains were resistant to gentamicin (GM). These GM resistances were not transferred to Escherichia coli K-12 strain CSH-2 by bacterial mating.
On the other hand, two types of R factors (Rkt1 and Rkt1+kt2) were obtained from a strain of Klebsiella pneumoniae ON-1 isolated from urine of a patient suffering from postoperative urinary tract infection at another hospital.
The properties of these R factors were as follows:
1) Rkt1 carried resistances to sulfanilamide (SA), streptomycin (SM), tetracycline (TC), kanamycin (KM), and GM. Rkt1+kt2 carried resistances to aminobenzylpenicillin (ABPC), carbenicillin (CBPC), and cephaloridine (CER) in addition to the above five drugs.
2) When the mating was made between ON-1 and CSH-2, the transfer frequency of Rkt1 was 1.5×10-5, whereas that of Rkt1+kt2 was 4.0×10-8 per donor cell.
3) Both R factors were fi-R factors, stable in CSH-2, and subsequently transferred to Escherichia coli K-12 strain W3104 at a high frequency.
4) The DNAs of both R factors were revealed to show the same buoyant density of 1.712g/cm3 in CsCl when analyzed by CsCl density gradient centrifugation.
Clinical significances of GM resistance and of the R factor were discussed.抄録全体を表示PDF形式でダウンロード (1605K) -
土田 正義, 加藤 哲郎, 西沢 理, 山口 脩, 森田 隆1976 年 67 巻 12 号 p. 1049-1056
発行日: 1976/12/20
公開日: 2010/11/29
ジャーナル フリーElectropyelogram (EPG) and electroureterogram (EUG) were simultaneously recorded in a patient of congenital hydronephrosis, with a resultant fact that a relationship between EPG and EUG in the patient of this disease was generally the same as in normal cases.
The morphologic examination of the hydronephrosis suggested that the most important point for successful pyeloplasty was to make a funnel-shaped renal pelvis. The operative procedure is also described.抄録全体を表示PDF形式でダウンロード (3675K) -
第1報 治療法と予後を中心として新島 端夫, 松村 陽右, 片山 泰弘, 森永 修, 池 紀征, 朝日 俊彦, 尾崎 雄治郎, 白石 哲朗1976 年 67 巻 12 号 p. 1057-1063
発行日: 1976/12/20
公開日: 2010/07/23
ジャーナル フリーClinical and prognostic studies were performed on 426 cases with tumor of the bladder, hospitalized and treated at the Department of Urology of Okayama University Hospital during 14-years from 1961 to 1974. Results are as follows:
1) As to age incidence of 426 cases, 38.3% occurs in the 7th decade. It is most frequently in this decade.
2) Male to female ratio is 5.6 with marked male predominance.
3) As to the morphologic classifications, papillary transitional cell carcinoma occupied 81%, grade II and III classified according to histological grade of A. U. A. Cancer Registry occupied 74% and the groups of stage O-B1 occupied 76%.
4) The 5-year-survival rate (observed survival rate) was presented in each initial treatment group as follows. TUC alone, 75.9%; TVC alone, 60.6%; partial cystectomy alone, 54.1%; simple total cystectomy alone, 25.6%. There is no difference between the group of combination of operative procedure with chemotherapy and/or external irradiation and the group of operation alone, except that simple total cystectomy with combination therapy (33.4%) was superior to operation alone (25.6%). This is not stastically significant, but implies that combination therapy should improve the 5-year-survival rate of the patients with bladder tumor.抄録全体を表示PDF形式でダウンロード (962K) -
松田 稔, 長船 匡男, 古武 敏彦, 園田 孝夫1976 年 67 巻 12 号 p. 1064-1069
発行日: 1976/12/20
公開日: 2010/07/23
ジャーナル フリーFifty cases with renal cell carcinoma treated in Osaka University Hospital during the past 19 years were histologically reviewed to discuss about the clinical significance of lymphocytic infiltration in and around the tumor and the type of neoplastic cell growth into the peritumoral zone. The results obtained were as follows.
1. Five year survival rate of the patients with the uninhibited (invasive) tumor growth was rather poor (36%) compaired with that of the cases with noninvasive growth pattern (50%).
2. The patients with prolific infiltration of the lymphocytes around the tumor seemed to have better prognosis than the cases with scanty lymphocytic infiltration.
3. The type of growth pattern or the degree of lymphocytic infiltration did not have a definite correlation with the nuclear atypism of the tumor cells.
4. Elevated ESR did not indicate the high degree of lymphocytic infiltration, but elevated body temperature was thought to be associated with fewer lymphocytic infiltration.抄録全体を表示PDF形式でダウンロード (2692K) -
大野 和美1976 年 67 巻 12 号 p. 1070-1084
発行日: 1976/12/20
公開日: 2010/07/23
ジャーナル フリーGenerally, the view is held that renal hypertension caused by movable kidney in excess of renin seretion results not only from reduction of renal perfusion pressure which is due to twisting, angulation and elongation of the renal pedicle but also from urinary stasis and stimulation of the renal nerves. The author investigated the relationship between the degree and blood pressure in 107 patiens with the movable kidney. Most of them were admitted to our clinic except for 3 outpatients. Moreover, renin measurements were carried out on blood plasma specimens obtained from both renal veins, peripheral vessels and inferior vena cava in 56 patients under supine posture, and on the samples from peripheral vessels in 33 patients after 4 hours' upright posture. The following results were obtained.
1) These patients were classified into 3 subgroups such as 69 normotensives, 20 borderline-hyper-tensives and 18 hypertensives. In ten (55.5 percent) of the hypertensive group the movable kidney was regarded as the etiologic factor and also in nine (45.0 percent) of the borderline-hypertensive group as the same. Additionally, even nine normotensive cases (13.0 percent) seemed to be suspected for the latent mechanism of renal hypertension.
2) Angulation or twisting of the renal pedicle may be the most possible cause of renal hypertension resulting from ischemia in these patients with the movable kidney.抄録全体を表示PDF形式でダウンロード (2161K)
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