Journal of the Japanese Association for Infectious Diseases
Online ISSN : 1884-5681
Print ISSN : 0021-4817
ISSN-L : 0021-4817
Volume 31, Issue 1
Displaying 1-4 of 4 articles from this issue
  • I. The improved Schick solution
    Tooru ARIGA
    1957 Volume 31 Issue 1 Pages 1-11
    Published: April 20, 1957
    Released on J-STAGE: November 25, 2011
    JOURNAL FREE ACCESS
    The author prepared an improved Schick solution, using the borate buffer solution for the dilution of toxin instead of the usual pepton water, in order to preventpseudoreaction. Field works were carried out with school boys in villages and in cities, in order to determine the criteria ofreadings for this solution.
    The results were as follows.
    1. The readings should be made on the fourth day, a day earlier than with the usual solution, and the boundary of positive reaction should be set on 10 mm diameter of redness. Contrast solution is not necessary.
    2. The rate of positive Schick test was estimated to be about 10% in cities and 20% in villages. This rate corresponds well to the higher incidence of diphtheria in villages than in cities.
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  • II. The new standardized Schick solution
    Tooru ARIGA
    1957 Volume 31 Issue 1 Pages 12-22
    Published: April 20, 1957
    Released on J-STAGE: November 25, 2011
    JOURNAL FREE ACCESS
    This time we conducted investigations using a new Schick solution modeled after the international standards.
    The results thus obtained were as follows.
    1. The readings should be made on the third a day, day still more earlier than with improved solution.
    2. The boundary between positive and negative reactions was likewise set on 10mm as theformer one.
    3. Therefore it may be advisable to also adopt the international standards of W.H.O. for the production of the Schick solution in our country.
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  • III. The international standardized Schick solution
    Tooru ARIGA
    1957 Volume 31 Issue 1 Pages 23-35
    Published: April 20, 1957
    Released on J-STAGE: November 25, 2011
    JOURNAL FREE ACCESS
    This time we used a Schick solution prepared by diluting the toxin with borate buffer solution which was obtained from the modified medium of Yoneda's sythetic and Pope's semi-synthetic medium.
    The results were as follows.
    1. The readings of the test should be made in 72 hours, that is, on the third day after injection. A diameter of 10 mm redness must be taken as the boundary of positive reaction.
    2. This solution is likely to have a little lower value than the wide-spread one in our country.
    3.L.R. value of Schick's solution has a great influence on the results of the test. Consequently, a simple and reliable method for the preparation of Schick solution after international standards is to be desired.
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  • Shinichiro UKAI, Tatsu IIMURA, Harumoto MURATA, Shozo FUJIWARA
    1957 Volume 31 Issue 1 Pages 36-40
    Published: April 20, 1957
    Released on J-STAGE: November 25, 2011
    JOURNAL FREE ACCESS
    Several liver function tests, especially flocculation tests have been carried out on scarlet fever patients, who were treated in the Toshima hospital from the year 1952 to 1954.
    The results were as follows.
    The determination of bilirubin in the serum and of urobilinogen in the urine already showed abnormalities in the beginning of the disease. The BSP-test regarded as a foreign body excretion test also broght about abnormal results in this stage. On the contrary, albumin metabolism tests such as Takata reaction, cobalt reaction, thymolturbidity test test and zinc sulfate turbidity test showed deviations only from the second week, reaching the maximum in the third or fourth week.
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