Journal of the Japanese Association for Infectious Diseases
Online ISSN : 1884-5681
Print ISSN : 0021-4817
ISSN-L : 0021-4817
Volume 37, Issue 12
Displaying 1-6 of 6 articles from this issue
  • Kazuhiro HANNYA, Tamotsu KONO, Tsuneo SEKIGUCHI, Kiyoshi IMAMOTO, Tsut ...
    1964 Volume 37 Issue 12 Pages 433-438
    Published: March 20, 1964
    Released on J-STAGE: November 25, 2011
    JOURNAL FREE ACCESS
    Grippe, meningitis, sepsis etc. are suspected in the early stage of leptospirosis icterohaemorrhagica and it is only in its icteric stage that epidemic hepatitis comes into question for differential diagnosis. Ten cases of leptospirosis ictero-haemorrhagica experienced by the authors from 1959 to 1963 demonstrated conspicuous differences from the other icteric diseases in haematology, erythorocyte sedimentation rate, renal disorder etc., and the prognosis of the former seemed to be influenced by the grade of renal insufficiency. Therefor, investigations were carried ut by the authors with great concern for the renal damage and the results were as follows:
    1. Leptospirosis ictero-haemorrhagica shows a marked renal impairment.
    Especially, in the early stage, glomerular filtration rate, renal blood flow and renal plasma flow are considerably lowered, and retarded excretion of P.S.P, uremia and proteinuria are also observed. These are important diagnostic criteria.
    2. During the later half of the 1st to the early half of the 2nd week, diuresis usually -occurs and renal functions are improved within a relatively short time.
    3. As a criterion for prognosis, improvement of renal function, i.e. diuresis is important.
    4. Epidemic hepatitis, which must be differentiated from the disease, usually demonstrates only a slight renal impairment. Leptospirosis ictero-haemorrhagica belongs undoubtedly to the category of hepatorenal syndrome.
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  • Shigeichi YAMAZAKI, Sadayoshi UEDA, Chikamune SHIRAKATA, Muneyuki MATS ...
    1964 Volume 37 Issue 12 Pages 439-445
    Published: March 20, 1964
    Released on J-STAGE: November 25, 2011
    JOURNAL FREE ACCESS
    An epidemic infantile diarrhea characterized by watery and white colored stool occurred among milk infants in Takaoka City of Toyama prefecture during the period from January to February 1962. Stools of nine patients were examined virologically and bacteriologically.
    1) No virus was isolated by the use of MK cell and HeLa cell. On the other hand, by the aerobic bactriological examination with SS, BTB and agar plate containing rabbit blood, known intestinal pathogenic bacteria and streptococci were not isolated.
    2) Staphylococci were isolated from four typical white colored stools by using No.110 and PP plate which were specially used for isolation of staphylococci. All these strains had the nature of pathogenic strain.
    3) All the isolated strains were proved to be resistant against penicilline, highly sensitive against streptomycine and chloramphenicol, and sensitive against tetracycline and erythromycine. These strains were proved to be more resistant against sublimate than the control strain.
    4) By the phage typing test, all the strains had the same pattern of 80/81/KS6 includ - ing 80 and 81 phage as the hospital staphylococci.
    5) From these results of the determination, staphylococci as well as virus must be recognized as the causative agent of watery and white colored diarrhea, Pseudocholera infantum.
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  • T. YANAGISHITA, H. MIYAJI, T. OGINO, Y. ITAZU
    1964 Volume 37 Issue 12 Pages 446-451
    Published: March 20, 1964
    Released on J-STAGE: November 25, 2011
    JOURNAL FREE ACCESS
    (I) In autumn 1962, two patients suffering from typhoid fever and two from paratyphoid fever were treated with oral dosis of 33-55 mg of Aminobenzyl penicillin per kilogram of body weight daily for 7 days.
    In one of the paratyphoid patients, the temperature fell from 40°C to 39°C, which continued, however, for further 4 days.
    The other paratyphoid patient on the contrary got higher temperature than he had before the treatment.
    The two typhoid patients did not show any tendency of the fall of temperature.
    (2) Growth of strains of Salm. typhi and Salm. paratyphi A, B from the patients were inhibited by 0.39-1.56 mcg/ml of aminobenzyl penicillin and 6.25-12.5 mcg/ml of Chloramphenicol.
    (3) No side effect was seen in any of the cases.
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  • Hiroshi TAJIMI, Yatsuka IMAGAWA
    1964 Volume 37 Issue 12 Pages 452-457
    Published: March 20, 1964
    Released on J-STAGE: November 25, 2011
    JOURNAL FREE ACCESS
    One carrier of typhoid (April, 1963) and another of paratyphoid-A bacilli (August, 1963) were treated orally with aminobenzyl penicillin (AB-PC) 2 gm. daily in four divided doses for five days.
    The pathogens in the feces remained negative from the third day of medication to the end of hospitalization.
    In successive examinations of A, B and C bile for two weeks, the pathogens in the biles remained negative from the fifth day of medication (Case No.1, typhoid carrier) and from the third day (Case No.2, parrtyphoid-A carrier) to the end of hospitalization.
    According to the plate method, the typhoid bacilli isolated were susceptible to less than 0.39 mcg/ml of AB-PC while the paratyphoid-A bacilli to 0.78 mcg/ml of the drug.
    It was concluded from the above that AB-PC was worthy of trying with typhoid carriers.
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  • Hiroshi TAKEDA, Makoto SAITO
    1964 Volume 37 Issue 12 Pages 458-460
    Published: March 20, 1964
    Released on J-STAGE: November 25, 2011
    JOURNAL FREE ACCESS
    Two patients of typhoid fever including a carrier were treated by oral administration of aminobenzyl-penicillin.
    In one of them, the symptoms in acute stage subsided rapidly, and the bacilli (S. typhi) from urine disappeared after oral use of aminobenzyl-penicillin. However, in another case, S. typhi was continuously proved from feces for a long time after the treatment.
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  • 1964 Volume 37 Issue 12 Pages 478-479
    Published: March 20, 1964
    Released on J-STAGE: November 25, 2011
    JOURNAL FREE ACCESS
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