Journal of the Japanese Association for Infectious Diseases
Online ISSN : 1884-5681
Print ISSN : 0021-4817
ISSN-L : 0021-4817
Volume 42, Issue 5
Displaying 1-3 of 3 articles from this issue
  • Naeo IKEDA
    1968 Volume 42 Issue 5 Pages 125-130
    Published: August 20, 1968
    Released on J-STAGE: November 25, 2011
    JOURNAL FREE ACCESS
    As mentioned in previous reports, it was clear that the epidemic hemorrhagic fever (EHG) could be induced to quite healthy persons by inoculation of the blood specimens collected from the patients with genuine EHF. Therefore, the agents of EHF were certainly considered to exist in the blood of patients in acute stage of EHF.
    Dr. Masaji KITANO found a specific species of tick, ‘Togedani’, attaching to rat and playing an important role as a carrier of the disease, and so he insisted that the togedani inhabiting the areas where, EHF was prevelent, might be a natural possessor of the agents. In addition, it was supposed that in such circumstances, other insects such as vermin, fleas, bed-bugs, flies, or mosquitoes might be also reservor of the agents at least transiently. However, because no soarlling blood-sucking insects could remain being active in serious cold of winter in the noreheastern part of China where EHF had been prevalent still in this season, these kinds of insects could be excluded from the object of investigation. The author examined the infectivity of fleas and lice isolated from patients, and acquisition of infectivity on the artificially incubated unstained louse line by stinging the patients with EHF. Thus, it was confirmed that the healthy persons would develop the disease by stinging of poisoning louse.
    It is not clear whether lice in the epidemic area naturally possess the agents of EHF, but it is doubtless that the poisoning lice which have sucked the blood from a healthy person, may cause him an infection of EHF. Therefore, it is concluded that a louse must be looked upon as a carrier of EHF.
    On the other hand, as to the flea, the author failed to confirm whether flea had infectivity of EHF to man, in consequence of several biological experiments.
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  • Hideo OTA, Shiro SAITO, Osamu HIKOSAKA
    1968 Volume 42 Issue 5 Pages 131-135
    Published: August 20, 1968
    Released on J-STAGE: November 25, 2011
    JOURNAL FREE ACCESS
    Comparison was carried out of two distinct types of serological procedures currently in use for the diagnosis of syphilis:(1) the procedures using cardiolipin antigan, viz. Ogata's complement fixation reaction, agglutination reaction and VDRL, and (2) those using Treponema Pallidum as antigen, viz. RPCF and FTA, in respect of sensitivity and biological false positivity.
    Sera tested were taken from patients and suspected persons with syphilis, pregnant women, and cancer patients.
    Results were as follows:
    1. Percentage of sccordance between results obtained by cardiolipin (CL) and Treponema Pallidumt (TP) methodds was 83-86, while between those by FTA and RPCF was 95.3. The comparatively high parallelism between two methods using TP antigen, so FTA and RPCF were considered to be due to the common antigenic constituents contained in them.
    2. Of CL-positive sera from cancer patients, cases to be considered to be bilogocial false positive by chequing with case history, clinical findings, and TP-methods, were 27 (62.8%). Of 23 sera showing positive RPCF, 7 (25.9%) were similarly interpreted to be biological false positive. Of 16 (37.2%) proved to be positive by FTA, noce was thought to be biological false posititve, so FTA seems to be the method of choice in specificity for sypjilis diagnosis.
    3. Negative conversion of the sera from patients after antisyphilitic treatment was observed earlier in FTA and RPCF than in the CL methods, this is indicating the importance of the two methods as index of the effect of antisyphilitic therapies.
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  • 1968 Volume 42 Issue 5 Pages 150-156
    Published: August 20, 1968
    Released on J-STAGE: November 25, 2011
    JOURNAL FREE ACCESS
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