Following the studies on the masking effect of human saliva upon the qualitative thiamine reaction, the author has performed similar studies of bile, and has obtained the following results. (1) In bile there is a factor which masks the qualitative thiamine reaction. (2) Judging from the behaviour on the ion-exchange resin (IRA-400), this factor is considered to be composed of two. (3) The thiamine which was produced by the masking effect of bile was its disulfide.
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