Juntendo Medical Journal
Online ISSN : 2188-2134
Print ISSN : 0022-6769
ISSN-L : 0022-6769
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Volume 30, Issue 1
Displaying 1-15 of 15 articles from this issue
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Contents
  • Scanning Electron Microscopic Findings of the Red Cells of Hereditary Spherocytosis
    AKIHIKO HOSHINO
    1984 Volume 30 Issue 1 Pages 59-66
    Published: March 10, 1984
    Released on J-STAGE: November 20, 2014
    DOIhttps://doi.org/10.14789/pjmj.30.59
    JOURNAL FREE ACCESS
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    Hereditary spherocytosis is the most common inheritated disorder of the red-cell membrane and is transmitted as an autosomal-dominant trait in 80 to 90 percent of the cases. The classic features are a congenital and familial hemolytic-process-associated splenomegaly and red cells that are spherical in shape. The author reported two families with this disease and also observed red cells morphologically in three of these cases by scanning electron microscope. As a result, spherocytes, discocytes and stomatocytes occupied 17 to 33%, 32 to 44%, and 30 to 51% of their specimens respectively. Their spherocytes varied in size and shape, and a seriously spherical shape was rare. An increased percentage of stomatocytes, which are precursors of spherocytes, was characteristic on scanning electron microscopic observations.
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  • An Experimental Study on Gas Resorption Mechanism in the Intrathoracic Cavity
    -Effects of Pure Oxygen Inhalation, Pulmonary Artery Ligation and Main Bronchus Occlusion-
    HIDETOSHI KUDO
    1984 Volume 30 Issue 1 Pages 67-76
    Published: March 10, 1984
    Released on J-STAGE: November 20, 2014
    DOIhttps://doi.org/10.14789/pjmj.30.67
    JOURNAL FREE ACCESS
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    In 57 dogs, artificial pneumothorax was induced by the instillation of various gases, and changes in intrathoracic partial gas pressures were measured by a blood gas analyzer following pulmonary artery ligation or main bronchus occlusion under room air or pure oxygen breathing. Following the instillation of pure oxygen into the intrathoracic space under room air breathing, PTO2 (partial pressure of oxygen in the intrathoracic space) showed a gradual decrease, and, after three hours, PTO2 decreased to half the initial level. Under pure oxygen inhalation, PTO2 was maintained at 640 mmHg, while PaO2 was about 530 mmHg. There were the same changes in PTO2 and PTCO2 following pulmonary artery ligation as with no ligation. Under pure oxygen breathing, PTO2 was maintained at 660 mmHg, while PaO2, decreased to 90 mmHg following main bronchus occlusion. This fact suggested that, in dogs under pure oxygen breathing, oxygen gas could reach the intrathoracic space from the alveoli through the visceral pleura. The mechanism of absorption of intrathoracic gas and the clinical application of oxygen inhalation in the treatment of spontaneous pneumothorax were discussed.
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  • A Study of Cytology in the Disease of the Biliay Tract
    -Device of Brushing Cytology of the Bile Duct and Comparison with Exfoliative Cytology of the Bile-
    OSAMU SATO
    1984 Volume 30 Issue 1 Pages 77-83
    Published: March 10, 1984
    Released on J-STAGE: November 20, 2014
    DOIhttps://doi.org/10.14789/pjmj.30.77
    JOURNAL FREE ACCESS
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    Exfoliative cytology of the bile is widely used, and the weak points of this method have been reported to be the small amount of cells and cell degeneration caused by bile. The author devised the technique of brushing cytology of the bile duct. In brushing cytology, many fresh cells can be obtained as in direct touch smear. Exfoliative cytology of the bile and brushing cytology were performed in 74 cases of malignant and benign lesions in the biliary tract. The accuracy rate of brushing cytology was higher than that of exfoliative cytology (brushing cytology, 93.2%: exfoliative cytology, 63.5%). In malignant lesions, brushing cytology was more accurate than exfoliative cytology (brushing cytology, 93.8% ; exfoliative cytology, 52.1%). In malignant lesions, brushing cytology was effective in cases of bile duct carcino ma, duodenal carcinoma, pancreas head carcinoma, and recurrence of gastric carcinoma. In conclusion, brushing cytology is a very useful method for the diagnosis of lesions in the biliary tract.
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