Juntendo Medical Journal
Online ISSN : 2188-2134
Print ISSN : 0022-6769
ISSN-L : 0022-6769
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Volume 30, Issue 3
Displaying 1-13 of 13 articles from this issue
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Contents
  • Clinical Study of the Relationship Between Gastric Acid Secretion and Group I Pepsinogen Levels in Peptic Ulcer Patients
    YOZO WATANABE, AKIO NOMI, KEIICHIRO KONDO
    1984 Volume 30 Issue 3 Pages 322-330
    Published: September 10, 1984
    Released on J-STAGE: November 20, 2014
    DOIhttps://doi.org/10.14789/pjmj.30.322
    JOURNAL FREE ACCESS
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    We studied the relationship between gastric acid secretion and serum group I pepsinogen (PGI) before and after subcutaneous injection of Histalog and insulin hypoglycemia stimulation in intractable peptic ulcer patients. The mean serum PGI levels in 9 gastric ulcer and 12 duodenal ulcer patients were 60.9±19.8ng/ml and 84.1±22.5ng/ml, respectively with the latter value being significantly higher than the former. Serum PGI after stimulation with Histalog and insulin hypoglycemia stimulation in hypersecretors was significantly higher than that of normosecretors. A significant relationship exists between PAO or.MAO and serum PGI after stimulation with Histalog. A statistically significant correlation was found between MAC, PAO or IAO and serum PGI after insulin hypoglycemia stimulation. This suggests that serum PGI must be mediated by the vagal nerves.
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  • Lupus Erythematosus with Neuropsychiatric Manifestations
    Classification and Characteristics of Systemic
    KEIKO SAKAI
    1984 Volume 30 Issue 3 Pages 331-341
    Published: September 10, 1984
    Released on J-STAGE: November 20, 2014
    DOIhttps://doi.org/10.14789/pjmj.30.331
    JOURNAL FREE ACCESS
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    The clinical and serological characteristics of 86 patients with systemic lupus erythematosus (SLE) and central nervous system (CNS) disease were studied. They had a significantly high incidence of cardiac murmur, abnormal electrocardiographic and cerebral spinal fluid (CSF) findings, hypohemoglobinemia and hypoprotenemia as compared with 242 SLE patients without CNS disease. In addition, the incidence of antibodies to asialo GM1, Sm and proliferating cell nuclear antigen (PCNA) was higher in those patients with CNS. The 86 SLE patients with CNS disease were divided into three groups : the first comprised patients with neurologic symptoms, seizures, cerebrovascular disesase (CVD), cerebral nervous disease, transverse myelopathy and so on ; the second, covered patients with psychosis (PS), and the third, patients with neuropsychiatric symptoms, seizure+PS, CVD+PS, and other neurological symptom +PS. The characteristics of these groups were studied. The first group showed a high incidence of abnormal findings of the ocular fundus and a lower CSF sugar level. No particular serological differences among these three group were observed. But it was suggested that anti-asialo GM1 antibody was related to CVD and the prognosis of patients with CVD was poor. Neuropathological manifestations were also studied in each group. The perivascular infiltrates of lymphocytes were observed in patients with seizures, but true arteritis of cerebral vessels was not found. Therapeutic analysis were also performed. Regardless of the dosage of prednisolone, the prognosis of patients with CVD was poor. Pulse therapy (methylprednisolone 1000mg/day x three days) was effective for the patients with transverse myelopathy.
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  • The Effect of Pancuronium Bromide on the Isolated Perfused Heart of the Rabbit
    HIDEMITSU TOKUDA
    1984 Volume 30 Issue 3 Pages 342-347
    Published: September 10, 1984
    Released on J-STAGE: November 20, 2014
    DOIhttps://doi.org/10.14789/pjmj.30.342
    JOURNAL FREE ACCESS
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    Isolated rabbit hearts were transferred to a modified Langendorff perfusing apparatus and perfused with Krebs-Henseleit solution. Pancuronium induced an increase in heart rate in the nonreserpinized preparation. However, this positive chronotropic effect was diminished in the reserpinized preparation. Furthermore, infusion of pancuronium caused a reduction in the strength of the myocardial wall tension and coronary flow rate in both preparations. It was postulated that the positive chronotropic effect of pancuronium may be due to endogenous catecholamines and pancuronium itself may have a negative inotropic effect on the isolated, perfused heart of the rabbit.
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  • Evaluation of the Descriptions of the Radiological Findings in Inpatient Charts at Juntendo University Hospital
    HITOSHI KATAYAMA, YOKO MARUBAYASHI, KIMIKO NISHIZONO, TERUKO SANO, KYO ...
    1984 Volume 30 Issue 3 Pages 348-353
    Published: September 10, 1984
    Released on J-STAGE: November 20, 2014
    DOIhttps://doi.org/10.14789/pjmj.30.348
    JOURNAL FREE ACCESS
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    Good descriptions on medical chart are essential for modern multidisciplinary medicine. In this particular series, evaluation of the descriptions of the radiological findings was carried out on medical records at Juntendo University Hospital. One thousand inpatient charts drawn up during calendar 1981 were randomly selected and descriptions of radiological findings were evaluated. In addition, fifty inpatient charts each were randomly selected from the Departments of Internal Medicine and Surgery. They were evaluated on the description of radiological findings in terms of date of the examination, method of the examination, contents of the report, recommendation of further examination and doctor's signature. There were 7096 requests for radiological examination in the 1000 randomly selected inpatient charts, and 3717 (52.4%) corresponding descriptions of the findings were present. The schema was the most popular medium of description (67%) followed by Japanese (16.9%) and foreign language (mainly English, 16.1%). The description of the findings was better in nonsurgical charts.The description of the special radiological examinations was better than nonspecial radiological examinations. The further evaluation of 100 surgical and nonsurgical charts showed a similar tendency. There were 404 descriptions in the surgical charts and 328 in the nonsurgical charts. Analyses of the descriptions showed the following results. The date of examination was seen in 39% of the surgical charts and 51% of the nonsurgical charts. The method of examination was seen in 57% of the surgical charts and 67% of the nonsurgical charts. The contents of the description were better in the nonsurgical charts. Recommendations for further examination were seen in 10% and 20% of the descriptions, and doctor's signatures were seen in 7% and 39% respectively. Offical reports were of course better on all aspects of the descriptions. The results we obtained were quite disappointing and further effort is strongly required for better clincal medicine and clinical research.
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