Juntendo Medical Journal
Online ISSN : 2188-2134
Print ISSN : 0022-6769
ISSN-L : 0022-6769
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Volume 32, Issue 3
Displaying 1-18 of 18 articles from this issue
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Contents
  • Pathological Studies on Pancreatic Diseases in the Experimentally Induced Abnormal Pancreatico-Choledocho-Ductal Junction
    FUJIHIKO SUZUKI
    1986 Volume 32 Issue 3 Pages 334-343
    Published: September 10, 1986
    Released on J-STAGE: November 21, 2014
    DOIhttps://doi.org/10.14789/pjmj.32.334
    JOURNAL FREE ACCESS
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    An abnormal pancreaticocholedochoductal junction is known to be associated with congenital biliary dilatation and various other biliary tract diseases. Recently, it has been suggested that this abnormal junction also causes pancreatic disease. In this study, a choledochopancreatic end-to-side ductal anastomosis was performed in 60 puppies, and the histopathological changes of the pacreas and biliary tract were examined. This experimental model of elongated choledochopancreatic common channel disorders caused changes similar to those of congenital choledochal dilatation in humans, and epithelial hyper-plasia with inflammation of the dilatated bile duct and the gallbladder was observed in a few long-term follow-up cases. In the pancreas, 16 of the 60 puppies showed degeneration of the pancreatic duct with periductal fibrosis. Severe degeneration and destruction of the pancreatic parenchyma were noted in three of the 60. All these findings suggest that the massive reflux of the bile acid and the biliopancreatic juice into the pancreatic duct, which is due to a long common channel, is one of the significant etiological factors in the development of acute and chronic pancreatitis.
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  • A Diagnostic Study of Detecting Colorectal Early Cancer
    MASAAKI MATUKAWA
    1986 Volume 32 Issue 3 Pages 344-352
    Published: September 10, 1986
    Released on J-STAGE: November 21, 2014
    DOIhttps://doi.org/10.14789/pjmj.32.344
    JOURNAL FREE ACCESS
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    There are sometimes sm cancers in polypoid lesions of more 0.6cm in diameter. Distant metastasis may be occasionally recognized in sm cancers. Therefore, polypoid lesions more than 0.6cm in diameter should be detected by examinations of the large bowel. X-ray study and endoscopy were performed to detect colorectal polypoid lesions was examined in 8,236 patients undergoing double contrast barium enema and 2,395 subjected to colonoscopy. The radiological false-negative rate of polypoid lesions measuring between 0.6 and 3.0cm in diameter was 3.3%. Of these radiological false-negative lesions, 84.6% were recognized at the rectosigmoid region, the other 15.4% proximal to the descending colon. For detecting polypoid lesions in the rectosigmoid region, endoscopy is performed more easily and recognized more lesions than barium enema. Comparing the false-negative rate of polypoid lesions proximal to th descending colon, the accuracy of endoscopy was similar to that of barium enema. From the above results, flexible sigmoidoscopy at the rectosigmoid region and barium enema proximal to the descending colon on the same day are an effective way to detect polypoid lesions. In this manner, 92.6% of the polypoid lesions more than 0.6cm in diameter can be detected.
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  • Experimental and Clinical Application of the Nd-YAG Laser in Ophthalmology
    KAYOKO KASHIMA
    1986 Volume 32 Issue 3 Pages 353-368
    Published: September 10, 1986
    Released on J-STAGE: November 21, 2014
    DOIhttps://doi.org/10.14789/pjmj.32.353
    JOURNAL FREE ACCESS
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    Experimental and clinical studies on the Nd-YAG laser were carried out. The CW Nd-YAG laser and the pulse train Nd-YAG laser have thermal effects on ocular tissues, so that retinal and choroidal photocoagulation is possible with different coagulation characteristics, as compared with the argon laser. The Nd-YAG laser coagulate deeper layers of the fundus without much damage to the retinal nerve fiber layer. Thermal effects are also applicable for laser iridotomy. The Q-switched Nd-YAG laser has the effect of photodisruption, which is useful for membrane cutting. Opaque pupillary membrane dissection and laser iridotomy were successfully performed without any serious complications.
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