Juntendo Medical Journal
Online ISSN : 2188-2134
Print ISSN : 0022-6769
ISSN-L : 0022-6769
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Volume 3, Issue 1
Displaying 1-9 of 9 articles from this issue
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  • Studies on Vermicidal Effect of Keratinolytic Enzyme
    Kocho SATO
    1957 Volume 3 Issue 1 Pages 1-8
    Published: February 10, 1957
    Released on J-STAGE: November 22, 2014
    DOIhttps://doi.org/10.14789/pjmj.3.1_1
    JOURNAL FREE ACCESS
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    Nematolyt which is kerationlytic enzyme drug has the following effects. 1. It brings forth the vermicidal effect by destroying and perishing and further dissolving quickly the cuticles of hog-ascarid, earthworm and leech. 2. When carrying out “Oral Administration”, it does not conspicuously change the mucous membrane of rabbit's alimentary canal. 3. The toxin of hog-ascarid, destroyed and seized by Nematolyt, makes the rabbit's red corpuscle resistance conspicuously decreased, and eosinophils increased. 4. It is also effective upon Cestoda in vitro or in vivo, but its efficacy, being weak, is much less than upon Nematoda. 5. Its efficacy, when lost in acid-liquid (pH 2.0), is irreversible. 6. Its action is bereaved by the liquid decocted from Maglolia hypoleuca. This process of function will be studied someday.
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  • Studies on Cystitis
    (I : Histological Studies of Cystitis)
    Tetsuo WATANABE
    1957 Volume 3 Issue 1 Pages 9-21
    Published: February 10, 1957
    Released on J-STAGE: November 22, 2014
    DOIhttps://doi.org/10.14789/pjmj.3.9
    JOURNAL FREE ACCESS
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    1. As part of the study on cystitis histological studies were carried out from the clinical viewpoint. 2. The materials studied were necroptic findings of 19 cases excluding those with urinary_bladder diseases, 14 cases were male and 9 cases female, with the age ranging from 50 days after birth to 92 years. 3. Elastic fibers, blood vessels and nerve tissues of sections from trigone, lateral wall and anterior wall, of the bladder were examined. 4. The development of elastic fibers show strong individual difference. Elastic fibers can be seen in tunica propria, intermuscular tissue, blood vessel wall, serosa, and within the muscle bundles. It is most abundaut in the tunica propria. The state of development of the connective tissne in the tunica propria shows 3 types. a) A band running parallele to the epithelium in the deep loose zone. b) A close-knit band just under the epithelium and those running parallele to the epithelium in each deep loose zone, i. e. those fibers ccmposing two bands. The two types mentioned above run an irregular course in other parts. c) Those showing general irregular course. 5. The elastic fibers in the shallow zone of tunica propria are thin and those in the deep zone thick. 6. The development of the elastic fibers was highest in the trigone followed by those in the lateral wall and the anterior wall. 7. There was no difference seen in the development according to sex. 8. The relationship between elastic fibers and age : Although definite conclusions cannot be drawn because pre-adolesccnt cases were not examined, those cases under one year showed very poor development and it is believed that elastic fibers continue their growth up to a certain age period. 9. The blood vessels in the tunica propria was most abundant in the trigone and was more evident in infants and in female. 10. The blood vessels run into spaces between epithelial cells. 11. The nerve fibers are distributed most abundantly in the muscle bundles.
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  • Studies on Strongyloidiasis
    (I) Epidemiological Observations in Amami-Oshima Island
    Hiroshi TANAKA
    1957 Volume 3 Issue 1 Pages 22-30
    Published: February 10, 1957
    Released on J-STAGE: November 22, 2014
    DOIhttps://doi.org/10.14789/pjmj.3.22
    JOURNAL FREE ACCESS
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    During the time between December 1955 to August 1956 the author made many examinations on stools of native villagers and school children on the island of Amami-Oshima in order to determine epidemiological aspects of the intestinal parasites, particularly Strongyloides stercolaris. In this study, thick fecal smears were mainly examined : however, this method was unsatisfactory for detecting them from the feces in which few larval Strongyloides were present. The concentration method by examing the sediment of emulsified fecal specimens or the cultivation method of feces by the same procedures as used for detecting hookworm larvae was proved to yield better results. At temperatures higher than 23°C, the movements of larval Strongyloides became quite intense. Therefor, larvae could be examined easily after warming the fecal specimens in cool weather. Microscopic examinations in many instances showed the path of the larvae through the feces quite well. Consequently, when the examiner took care of the slide, the larvae could be found very easily even in the specimens in which few larvae existed. Among 721 native villagers in the southern part of Oshima Island, 53 individuals (7.4%) were found to harbor Strongyloides stercolaris. The age and sex incidences of Strongyloides are shown in figure 4 (a) and have illustrated no great differences in percentage of infestation among the groups. Hookworm infestation above the 10-19 year age groups in the villagers showed a higher percentage in the male than in the female. Among 3,741pupils (5-18years), 31 individuals (0.83%) contained Strongyloides stercolaris. In Comparisons cf infestations of Strongyloides, hookworms, Ascaris, Trichuris between age groups, place of residence (Comparison Naze city with surrcunding villages) and sex of the pupils, percentage of infestation of Strongyloides among pupils showed no great differences between comparative table of age, locality and sex. It has been shown hookworms infest great numbers of older children thereby showing a much different epidemiologcal aspects between the hookworms and Strongyloides than had been expected heretofore.
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  • Studies on The Estimation of The Grade of Disability in The Cardio-Pulmonary Function of Silicotics
    Report 1 : On The Oximeter-Rate during and after The Inhalation of Pure Oxygen
    Toshio MIYAZAKI
    1957 Volume 3 Issue 1 Pages 31-37
    Published: February 10, 1957
    Released on J-STAGE: November 22, 2014
    DOIhttps://doi.org/10.14789/pjmj.3.31
    JOURNAL FREE ACCESS
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    In order to estimate the grade of disability on silicotic patients, the author conduced various analysis of the oximeter-rate obtainable upon pure oxygen inhalation and concluded as follows : 1. When the oximeter-rate of both normal and silicotic group were analysed by “γ-index method” utilizing coefficient of correlation, the results indicated that there are significant differences between normal and silicotic groups (P<0.01), and furthermore significant differences between each degree of silicosis (P<0.05). 2.Statistical differences are found between normal and silicotic groups and also between SI and SII in delay-time. 3.In saturation-time, statistical differences were observed between normal and silicotic groups (P<0.05), and statistical differences were recognized between SI and SIII. Thus, the analysis of the oximeter-rate upon inhalation of pure oxygen by silicotics is considered to be useful as a simple preliminary screening test to detect the grade of pulmonary disability in silicotics.
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