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清水
原稿種別: 本文
1955 年 9 巻 p.
172-
発行日: 1955年
公開日: 2017/12/22
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清水
原稿種別: 本文
1955 年 9 巻 p.
172-
発行日: 1955年
公開日: 2017/12/22
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高田
原稿種別: 本文
1955 年 9 巻 p.
172-
発行日: 1955年
公開日: 2017/12/22
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高田
原稿種別: 本文
1955 年 9 巻 p.
172-
発行日: 1955年
公開日: 2017/12/22
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高田
原稿種別: 本文
1955 年 9 巻 p.
172-
発行日: 1955年
公開日: 2017/12/22
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小森 三郎
原稿種別: 本文
1955 年 9 巻 p.
173-180
発行日: 1955年
公開日: 2017/12/22
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南崎 哲朗
原稿種別: 本文
1955 年 9 巻 p.
181-187
発行日: 1955年
公開日: 2017/12/22
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The excretion of thiamine may presumably be taken place in the stomach, intestines, salivary glands, sweat glands, etc. in addition to the kidney. In adult rabbit both the renal arteries were ligated and thiamine was given. The fate of the administered thiamine was observed histochemically in different organs. Under the renal insufficiency, a compensatory hyperfunction of other thiamine-excreting organs was observed. The excretion was obviously greater in the small intestine than in the stomach, large intestine, liver, gall bladder and salivary gland.
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南崎 哲朗
原稿種別: 本文
1955 年 9 巻 p.
188-193
発行日: 1955年
公開日: 2017/12/22
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The following findings were obtained by the histochemical study of thiamine in excised intestines of rats, which were kept alive in 50 ml of Ringer solution containing 500μg of thiamine, 525μg of thiamine allyldisulfide and 525μg of thiamine propyldisulfide at 38℃, for 5,15,or 20 minutes. (1) In 5 minutes, thiamine diffusion was observed only in the mucous epithelium. The extent of diffusion was similar in the duodenum, the jejunum, and the ileum. There was no difference between thiamine allyldisulfide and thiamine. (2) In 15 and 20 minutes : (a) An obvious absorptionpicture was observed. (b) The increased thiamine in the mucous membranes was chiefly of the free form, and the increase of ester form was very slight. (c) The thiamine allyldisulfide group was more easily absorbed by the intestines than thiamine-hydrochloride. (d) With regard to phosphorylation in the mucous membranes of the intestines, there was no marked difference between thiamine allyldisulfide and thiamine.
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南崎 哲朗
原稿種別: 本文
1955 年 9 巻 p.
193-201
発行日: 1955年
公開日: 2017/12/22
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(1) When thiamine allyl (or propyl) disulfide was ingested by rats, thiamine-absorption picture of the small intestines, especially from the anal end of the duodenum to the upper part of the jejunum, was observed more clearly than in any other parts of the intestines and the fluorescence was more striking than when thiamine was used. (2) A part of thiamine was phosphorylated in the mucous membrane of the small intestine, but the greater part of thiamine diffused into the membrane in a free form. (3) The thiochrome fluorescence of the liver, the heart, the kidney, or the pancreas was more marked in the group of rats administered with thiamine allyl (or propyl) disulfide than in that administered with thiamine. (4) The phosphorylation rate of thiamine allyl (or propyl) disulfide in the liver was a little higher than that of thiamine.
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清水
原稿種別: 本文
1955 年 9 巻 p.
201-
発行日: 1955年
公開日: 2017/12/22
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田中 久左衛門
原稿種別: 本文
1955 年 9 巻 p.
202-207
発行日: 1955年
公開日: 2017/12/22
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1. All control rats with a total vitamin A-deficiency die within two weeks after an suspension of increase in the body weight. 2. Daily administrations of less than 3 I.U. of either natural or synthetic vitamin A oil do not prevent the death of animals. When 3 I.U. are given, the animals recover, no marked difference in effect being found between the two oils. But the growing curves increase steeper with the natural than with the synthetic oil. 3. Within the physiological doses, the rate of recovery increases proportionally to the amounts of administration. It varies almost proportionally to the values observed by the Beckman's spectrophotometer.
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高田
原稿種別: 本文
1955 年 9 巻 p.
207-
発行日: 1955年
公開日: 2017/12/22
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高田
原稿種別: 本文
1955 年 9 巻 p.
207-
発行日: 1955年
公開日: 2017/12/22
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高田
原稿種別: 本文
1955 年 9 巻 p.
207-
発行日: 1955年
公開日: 2017/12/22
ジャーナル
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田中 久左衛門, 落合 彦人
原稿種別: 本文
1955 年 9 巻 p.
208-213
発行日: 1955年
公開日: 2017/12/22
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Using active glyceroldichlorohydrine and fluorescence-microscope, vitamin A, rhodopsin and fat in the retina were observed histochemically. (1) Irrespective of light- or dark-adaptation, vitamin A is always found in the pigment epithelial cells of the retina of carps, rats and bats, where rhodopsin is seen only at dark adaptation. Vitamin A is not found in chicks and love-birds in whom rhodopsin fails. In chicks and love-birds, coloured fat drops are seen at light adaptation and they increase considerably at dark adaptation. (2) Vitamin A in the outer segments of the rods is used for formation of rhodopsin. Riboflavin also participates in this process. (3) The shorter the wave-length of light, the stronger the effect of changing rhodopsin into vitamin A. (4) The amount of vitamin A needed for the formation of rhodopsin varies according to the species of animals and of vitamin A. (5) Generally speaking fat is found in a larger amount during light-adaptation, but it varies in different animals. (6) The distribution of vitamin A does not always run parallel with the quantity of fat.
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石井 隆一郎, 岩垣 智恵子
原稿種別: 本文
1955 年 9 巻 p.
213-217
発行日: 1955年
公開日: 2017/12/22
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β-Carotene has been reported to be lower than vitamin A in the growth promoting potency when used without adding adequate amounts of α-tocopherol. The investigation was undertaken to study the destruction of carotene in the synthetic gastric juice by the effects of simultaneous presence of lipoxidase in foods and the strong acidity of the gastric juice. It showed that carotene was lost more than expected, in some cases nearly one half of the potency by both lipoxidase and the gasric juice.
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加賀谷 晃
原稿種別: 本文
1955 年 9 巻 p.
217-221
発行日: 1955年
公開日: 2017/12/22
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25g of skimmed milk were given every day to 19 children with nutritional dystrophy. Estimation of riboflavin in their blood was made before, on the 36th and the 93rd day after the beginning of administration of the milk. A gradual increase in riboflavin of blood was found in 10 cases, 7 of which showed an improvement of ariboflavinotic signs. Another 9 cases showed temporary drops in riboflavin level of blood on the 36th day of the administration. In 3 of these 9 cases an exacerbation of ariboflavinotic sings was noticed. The temporary decrease in the riboflavin content of blood during the administration of the skimmed milk might be attributed to a simultaneous decrease in the red cell count, which was probably resulted from more rapid increase of plasma volume than red cell formation.
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深町 千晴, 黒木 柾吉, 桜井 芳人
原稿種別: 本文
1955 年 9 巻 p.
221-224
発行日: 1955年
公開日: 2017/12/22
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Riboflavin converts into lumiflavin when irradiated in alkaline solution, but when fructose is present it also changes to leucoflavin in the same time. As a result, the formation of lumiflavin is low because leucoflavin is not photolysed in this condition. Aeration at the time of irradiation prevents the formation of leucoflavin, and then conversion to lumiflavin takes place as in the ordinary case. Since some natural sources such as fruit juices, the riboflavin content of which should be determined, contain considerable amount of fructose, the authors recommend an aeration at the stage of photolysis in the normal "lumiflavin method" for the estimation of riboflavin.
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高田
原稿種別: 本文
1955 年 9 巻 p.
224-
発行日: 1955年
公開日: 2017/12/22
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高田
原稿種別: 本文
1955 年 9 巻 p.
224-
発行日: 1955年
公開日: 2017/12/22
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高田
原稿種別: 本文
1955 年 9 巻 p.
224-
発行日: 1955年
公開日: 2017/12/22
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高田
原稿種別: 本文
1955 年 9 巻 p.
224-
発行日: 1955年
公開日: 2017/12/22
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上久保 正
原稿種別: 本文
1955 年 9 巻 p.
225-226
発行日: 1955年
公開日: 2017/12/22
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Investigations on the stability of vitamin B_<12> in activated sludge showed that the vitamin was very stable in drying in the sun and in infra red ray, while drying in thermostat at 100-105℃ destroyed the vitamin depending upon the duration of heating.
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高田
原稿種別: 本文
1955 年 9 巻 p.
226-
発行日: 1955年
公開日: 2017/12/22
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小国 義親
原稿種別: 本文
1955 年 9 巻 p.
227-231
発行日: 1955年
公開日: 2017/12/22
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Waste liquor from acetone-butanol factory contains 1.1-2.7μg/dl of vitamin B_<12>. For the purpose of recovering vitamin B_<12> from the waste liquor, several conditions for adsorption on active carbon and elution with various solvents were investigated. The result that the concentrates contained only about 5μg/g, showed that the plan would be impractical.
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堀田 一雄, 滝口 きよ子
原稿種別: 本文
1955 年 9 巻 p.
232-234
発行日: 1955年
公開日: 2017/12/22
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In 1951 Takiguchi isolated four kinds of bacteria from soil, tentatively named strain A, B, C and D, which decomposed riboflavin. Bacteriological examinations have been made to know if they are of the same kind as the riboflavin decomposing bacteria discovered by Foster. The results showed that strain A was Bacillus fusiformis, strain D one of its variant, while strain B and C belonged to Bacillus circulons. Thus the bacteria examined were found to be quite different from Foster's bacteria, Pseudomonas.
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高田
原稿種別: 本文
1955 年 9 巻 p.
234-
発行日: 1955年
公開日: 2017/12/22
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高田
原稿種別: 本文
1955 年 9 巻 p.
234-
発行日: 1955年
公開日: 2017/12/22
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那須 嘉輝
原稿種別: 本文
1955 年 9 巻 p.
235-239
発行日: 1955年
公開日: 2017/12/22
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In normal blood plasma the average value of vitamin A was 152±10 I.U.%, and that of carotene 50±7μg%. In the vitamin A tolerance curve, the highest peak was observed after 5 hours. The vitamin A content of whole blood varied from 51 to 58% of that in plasma. In liver diseases and in several pulmonary tuberculosis, the plasma vitamin A level was lowered. The reduction took place correspondingly to the degree of liver damage, but not to that of jaundice. In renal diseases, the vitamin A level was often increased considerably.
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那須 嘉輝
原稿種別: 本文
1955 年 9 巻 p.
239-242
発行日: 1955年
公開日: 2017/12/22
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The vitamin A content in the liver was measured in rats. In acute toxic hepatitis and liver finbrosis the viamin A content was found to be reduced, but no change in fatty liver. The vitamin A content was kept normal when treated with chloropromazine. No correlation was found between the vitamin A content in the liver and the degree of liver damage.
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那須 嘉輝
原稿種別: 本文
1955 年 9 巻 p.
242-244
発行日: 1955年
公開日: 2017/12/22
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During stimulation of the sympathetic center, the vitamin A value in the liver decreased by 43% after 60 minutes. Cold stimulation caused a slight decrease after 60 minutes. The vitamin A content returned to normal or even exceeded it after 24 hours. A simultaneous use of chloropromazine suppressed these changes due to stimulation.
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森島 忠
原稿種別: 本文
1955 年 9 巻 p.
244-246
発行日: 1955年
公開日: 2017/12/22
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Estimation of riboflavin contents in colostrum and mature milk from the same subjects showed that the former was richer in riboflavin both free and ester form. Investigation on the monthly variation of riboflavin contents in breast milk indicated that higher levels of the vitamin were observed in the first month, while no significant change was recognized thereafter. Similar results were obtained from the experiments on cow's and goat's milk.
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森島 忠
原稿種別: 本文
1955 年 9 巻 p.
246-252
発行日: 1955年
公開日: 2017/12/22
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Hourly fluctuation of riboflavin contents in breast milk after oral, subcutaneous or intravenous administration of the vitamin to healthy women was examined. Greatest fluctuation was observed with intravenous injection and lowest with oral administration. The behavior of riboflavin administered subcutaneously resembled that with intravenous injection. Riboflavin contained in milk for 5 hours was only about sixtieth of the vitamin excreted in urine for the same hours. Consequently, the fluctuation of riboflavin contents in breast milk after administration of the vitamin seemed to be small, but marked.
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森島 忠
原稿種別: 本文
1955 年 9 巻 p.
252-254
発行日: 1955年
公開日: 2017/12/22
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X-ray analysis by Debye-Scherrer's powder method was used to find the difference between riboflavin and araboflavin. The results showed that the numbers of diffraction rings were equal (8 rings), but were some differences in d-value and the strength of diffraction rings.
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高田
原稿種別: 本文
1955 年 9 巻 p.
254-
発行日: 1955年
公開日: 2017/12/22
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高田
原稿種別: 本文
1955 年 9 巻 p.
254-
発行日: 1955年
公開日: 2017/12/22
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森 高次郎, 内藤 幸次
原稿種別: 本文
1955 年 9 巻 p.
255-262
発行日: 1955年
公開日: 2017/12/22
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巽
原稿種別: 本文
1955 年 9 巻 p.
263-264
発行日: 1955年
公開日: 2017/12/22
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深野
原稿種別: 本文
1955 年 9 巻 p.
264-265
発行日: 1955年
公開日: 2017/12/22
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加藤
原稿種別: 本文
1955 年 9 巻 p.
265-266
発行日: 1955年
公開日: 2017/12/22
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村田
原稿種別: 本文
1955 年 9 巻 p.
266-
発行日: 1955年
公開日: 2017/12/22
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堀田 一雄
原稿種別: 本文
1955 年 9 巻 p.
267-277
発行日: 1955年
公開日: 2017/12/22
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上久保
原稿種別: 本文
1955 年 9 巻 p.
277-
発行日: 1955年
公開日: 2017/12/22
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高田
原稿種別: 本文
1955 年 9 巻 p.
277-
発行日: 1955年
公開日: 2017/12/22
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南条 久
原稿種別: 本文
1955 年 9 巻 p.
278-281
発行日: 1955年
公開日: 2017/12/22
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Mice were used to check the LD_<50>, with thiamine allyldisulfide (TAD), thiamine propyldisulfide (TPD) and thiamine. The former two showed a less toxic effect than the latter.
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南条 久
原稿種別: 本文
1955 年 9 巻 p.
282-285
発行日: 1955年
公開日: 2017/12/22
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Using pure crystals of TAD and TPD, growth tests were made on albino rats, and the result was compared with that of ordinary thiamine. TAD and TPD showed a more intense effect than the latter.
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南条 久
原稿種別: 本文
1955 年 9 巻 p.
286-289
発行日: 1955年
公開日: 2017/12/22
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The bradicardia method was performed with rats administered with TAD and TPD. It was found that TAD and TPD had a more active curative effect on thiamine deficiency than ordinary thiamine.
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南条 久
原稿種別: 本文
1955 年 9 巻 p.
290-293
発行日: 1955年
公開日: 2017/12/22
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On rats adminstered with TAD or TPD, observations were made on the affinity of the chemicals to the tissues of visceral organs, as well as on the ratio of free thiamine content in the liver as against the total quantity of thiamine. The thiamine content in the liver, stomach, small intestines and blood of a rat, to which TPD had been supplied orally, always showed a higher value than that of another rat to which ordinary thiamine had been supplied. It was also ascertained that in the albino rat or mouse, phosphorization took place easier with TAD than with ordinary thiamine.
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南条 久
原稿種別: 本文
1955 年 9 巻 p.
293-295
発行日: 1955年
公開日: 2017/12/22
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In order to know whether TAD and TPD are decomposed by thiaminase, it was examined if TAD or TPD mixed with fern juice containing thiaminase in a test tube, was decomposed, and also if TAD, orally given with fern, was decomposed within the intestines of the animals. It was found that TAD, quite different from ordinary thiamine, was never decomposed by thiaminase either in vivo or in vitro.
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上原 喜八郎, 村松 一郎, 蒔田 政見
原稿種別: 本文
1955 年 9 巻 p.
296-301
発行日: 1955年
公開日: 2017/12/22
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The oxidation of glucose-6-phosphate, 6-phosphogluconate and ribose-5-phosphate in the presence of yeast autolysate is promoted by addition of vitamin K_3 as well as other derivatives of naphthoquinone. The comparative activities of naphthoquinone and its derivatives are shown. The oxidation of succinate, lactate and alcohol by animal tissue is also promoted by addition of vitamin K_3. In the systems in which diphosphopyridine nucleotide (DPN) or triphosphopyridine nucleotide (TPN) is concerned, vitamin K_3 acts as a hydrogen carrier, passing on hydrogen of reduced DPN or TPN to oxygen in the presence of yellow enzyme.
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