Since observations have been carried out in Part I and Part II on the fluctuation of weight of those pulmonary tuberculosis patients who underwent collaps therapy, either artificial pneumothorax or thoracoplasty, with desired results, we have to turn to the observation on the relations between the weight of those patients six months after the operation and their respiratory function, their basal metabolism and their results of Thorn's test.
1. The relation between the weight of the patients who had undergone collapse therapy, either artificial pneumothorax or thoracoplasty, and their respiratory function was studied. And the result was that those who gained weight proved to have more maximal breathing capacity, respiratory reserve and vital capacity than those who lost weight.
2. Six months after thoracoplasty, 16 patients (out of 20 who showed increase of basal metabolic rate) lost weight. But 20 patients (out of 30 who had normal metabolic rate) lost weight, too. So decrease of weight could not be said to be caused only by abnormal basal metabolism.
3. The results of the application of Thorn's test to the patients, who underwent thoracoplasty six months before, show that those who have normal percent-change of eosinophile are more likely to gain weight and less likely to lose weight than those who have abnormal percent-change of eosinophile. In other words, we have to take into account the influence of eudocrine system (especially that of suprarenal gland) when we consider the fluctuation of weight after the adoption of collapse therapy.

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In the previous report, it was found that the consumption of asparagine was higher in streptomycin resistant tubercle bacillus than in streptomycin sensitive strain. The fact was elaborated enzymatically.

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In the preceding experiments, glycerol was used as the source of carbon in the culture medium. This time, the decomposition of tyrosine by the tubercle bacilli was investigated by changing the composition of medium.

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For the purification of the tuberclin, ultra-filtration is most desirable since it does not cause any denaturation of the protein which is the active principle of tuberculin.

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Proteins A, B and C and polysaccharides I and II from the unheated part, and proteins hA, hB ani hC and polysaccharides h I and h II from the heated part of the same culture filtrate were examin-d, as to their chemical constituents and tuberculin activities and the influence of heating on tuberculin was also investigated on the basis of the results of examination.

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Histochemical study was performed on the curative effect of SM and INAH administration on the experimental tuberculosis of guinea pigs. Stainings employed were hematoxylin, eosin stain, anilin fuchsin stain for tubercle bacilli, silver stain for fibers, Hotchkiss' polysaccharide stain, metachromasia of toluidine blue. methyl-green pyronin stain, Feulgen's stain for DNA, alkaline phosphatase reaction, acid phosphatase reaction, esterase reaction, lipase reaction, ATPase reaction, alizarin stain and Kossa's reaction. The results obtained are as follows:

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1. Primary tuberculosis infection through the skin of a nurse aged 27 is presented. She had the infection at the age of 17 while she had been a positive tuberculin-reactor by BCG.
2. As her tuberculin reaction had been negative, she received BCG inoculation and her tuberculin reaction became positive. Two years after the positive conversion of her tuberculin reaction. she developed suddenly a high fever with right axillary adenoids. Tubercule bacilli were found from the smears of the axillary nodes. Then, her skin reaction to tuberculin became strong positive with vesicle. Primary focus was discovered and then the chance of the infection was confirmed. It is very interesting that her tuberculin reaction before and after the infection were frequently examined.
3. Six weeks after the onset, she developed right axillary nodular swelling (about twice a hen's egg) which was followed by fluctuatiol. Two months later right supraclavicular nodes enlarged, and three and a half months later the patient's temperature curve became normal with occasional elevations. By the end of one year and three months, there developed left coxal joint tuberculosis and right pulmonary tubercculosis. Thereafter, from the right axillary and supraclavicular nodes and left coxal joint spontaneous drainage occurred, but all these drains healed within 4 to 5 years. Thereafter, no advance was observed in the pulmonary tuberculosis and six years later the chest roentgenogram showed calcified scar in the right upper lobe and adjacent to the left hilum. At present, this patient has def ormities of the left coxal joint and is walking with the help of stick.

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A series of experiments were made on 14 patients of pulmonary tuberculosis to determine the increase of caloric consumption after the experimental diet whcih container, 1 827 cal. and 15% protein. The increased consumption was measured every half to one hour after the meal by testing the gaseous metabolism for five minutes, using the Douglas bag method. The results were as follows:
The increase of caloric consumption varies from 24 to 65 cal. (averaged 41.1 cal.), and it correlates significantly to the physical constitution of individual patient, especially to the width of body surface and the standard basal metablolism (correlation coefficient 0.602 and 0.632 re: pecpectively).

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