Kekkaku(Tuberculosis)
Online ISSN : 1884-2410
Print ISSN : 0022-9776
ISSN-L : 0022-9776
Volume 58, Issue 10
Displaying 1-6 of 6 articles from this issue
  • Keisuke NISHIWAKI, Mitsuru IWAKURA, Satoshi SUGIYAMA, Izumi AMANO, Kao ...
    1983 Volume 58 Issue 10 Pages 509-514
    Published: October 15, 1983
    Released on J-STAGE: May 24, 2011
    JOURNAL FREE ACCESS
    This paper presents clinical features of ten tuberculous patients out of five hundred and twelve chronic renal failure patients on hemodialysis. The incidence was 2.0%. The average age at onset was fifty one years old, and males were predominant. The affected organs were pleura, lung and cervical lymphnodes, with a ratio of the former two to the latter two to one, and one case of miliary tuberculosis.
    All had pyrexia and positive C reactive protein test and most cases presented leukocytosis with shift to left, relative lymphocytopenia and accelerated erythrocyte sedimentation rate, which suggested acute bacterial infections. Tuberculin skin test was positive in 7 out of 8 tested cases. Chest X-ray findings were small exudative parenchymal lesion and/or pleural effusion. Tuberculosis developed within five months after initiating hemodialysis in ninety percent of the cases. All patients responded well to antituberculous chemotherapy using isoniazid, rifampicin and ethambutol, and the outcome was favorable among them.
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  • 1, Survival Rates of Mycobacteria in Saline after Treatment with NaOH
    Kenji MARUMO, Yoshio AOKI
    1983 Volume 58 Issue 10 Pages 515-520
    Published: October 15, 1983
    Released on J-STAGE: May 24, 2011
    JOURNAL FREE ACCESS
    Bactericidal effects of 4% and 1% NaOH solution on a variety of mycobacteria (reference strains) suspended in saline were examined at various intervals (1, 5, 10 and 30 minutes) after the suspension. The bactericidal effect was evaluated by the survival rate (Mean±S.E.) in com parison with the control.
    The results obtained were as follows. After the pretreatment for 5 minutes with 4% and 1% NaOH solution, the survival rates of Mycobacterium tuberculosis H37Rv (IID 591) were 63±8% and 74±4%, respectively. Those of M. kansasii (p1.) were 35±12% and 43±8%, of M. scrofulaceum (ATCC 19881) were 29±10% and 32±10%, of M. intracellulare (ATCC 15984) were 16±4% and 12±6%, and of M. fortuitum (ATCC 6841) were 1% and 17±4%, respectively. After the pre treatment for 30 minutes with 4% and 1% NaOH solution, the survival rates of M. tuberculosis H37Rv were 45±3% and 55±8%, of M. kansasii were 18±6% and 7±4%, of M. scrofulaceum were 16±6% and 10±6%, of M. intracelluare were 11±3% and 8±6%, and of M. fortuitum were 0% and 4±2%, respectively.
    The longer the pretreatment time with both concentrations of NaOH, the lower the survival rates of all mycobacteria. Moreover, there were marked differences in the resistance to NaOH among the species of atypical mycobacteria and it was demonstrated that M. fortuitum was damaged most markedly by the treatment with NaOH solution. In this experiment, M. fortui turn could not grow on Ogawa egg media after the treatment with 4% NaOH for 10 minutes.
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  • Terufumi SHIMODA, Tetsuro KANDA, Yoji SUZUYAMA, Keizo YAMAGUCHI, Masak ...
    1983 Volume 58 Issue 10 Pages 521-527
    Published: October 15, 1983
    Released on J-STAGE: May 24, 2011
    JOURNAL FREE ACCESS
    A rare case with pulmonary infection due to M.scrofulaceum was reported.
    The patient was 43 years old male with pneumoconiosis as underlying disease, and it was considered that this pneumoconiosis was concerned with the pulmonary infection due to M. scrofulaceum.
    The M. scrofulaceum isolated from sputum of this patient was sensitive to streptomycin (SM) and ethambutol (EB), but resistant to isoniazide (INH) and rifampicin (RFP).
    Although combination therapy with SM, EB, INH and RFP was applied for over 5 months, improvement of infiltrative shadow with a cavity was not clearly observed. Then, a right upper lobectomy was performed after chemotherapy because of poor response against the administra tion of antituberculosis agents.
    The existence of acid-fast bacilli in a lesion was recognized with Ziel-Neelsen stain of the lung specimen obtained by operation, although no growth was observed on culture.
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  • Kimiko ICHIMURA, Yuji NAGAE, Takahiko SUGIURA, Katsutoshi TAKADA, Mune ...
    1983 Volume 58 Issue 10 Pages 529-532
    Published: October 15, 1983
    Released on J-STAGE: May 24, 2011
    JOURNAL FREE ACCESS
    A case of pulmonary disease due to M. fortuitum infection was reported. A 56 year old woman had a five year history of hemosputum with recurrent gastric ulcer.
    The chest X-ray film revealed infiltrates in both lungs, in the right upper and left lingular areas, and M. fortuitum was repeatedly isolated from the sputum during the period of five years. The bronchogram showed left lingular bronchiectasis, which was suspected to be a predisposing factor together with recurrent gastric ulcer.
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  • TUBERCULOSIS CONTROL PROGRAMME IN TECHNICALLY ADVANCED COUNTRIES
    Tadao SHIMAO
    1983 Volume 58 Issue 10 Pages 533-540
    Published: October 15, 1983
    Released on J-STAGE: May 24, 2011
    JOURNAL FREE ACCESS
    The epidemiological situation of tuberculosis has been improving markedly in Japan, however, it is still about 15 to 20 years behind the situation of most advanced countries such as Netherland, Scandinavian and North American countries. As problems of tuberculosis control programme in these countries nowadays might be a problem for Japan 10 to 15 years ahead, the author tried to make a review of tuberculosis control programme in technically advanced countries.
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  • CLINICAL APPLICATIONS OF THE TUBERCULIN SKINTEST
    1983 Volume 58 Issue 10 Pages 541-562
    Published: October 15, 1983
    Released on J-STAGE: May 24, 2011
    JOURNAL FREE ACCESS
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