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Volume 60, Issue 2
Displaying 1-6 of 6 articles from this issue
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Takashi HARADA, Tamio TANAKA, Shinichiro MATSUO, Hiroyuki OZONO, Akimi ...1985 Volume 60 Issue 2 Pages 53-58
Published: February 15, 1985
Released on J-STAGE: May 24, 2011
JOURNAL FREE ACCESSThirty four patients with tuberculosis were identified over a 17 year period in a group of 643 patients undergoing peritoneal and hemodialysis. The incidence of tuberculosis was more frequent in the early stages of dialysis. Sixteen patients were diagnosed definitely as having lymphogenic tuberculosis (6), miliary tuberculosis (5), pulmonary tuberculosis (1), tuberculous pleurisy (1), tuberculous peritonitis (1) and tuberculous arthritis (1), and the other 18 patients, 14 having fever of unknown origin and 4 pleurisy, were diagnosed ther apoiticaly as having tuberculosis. The diagnosis of tuberculosis in dialysis patients was difficult because the symptoms were nonspecific, there were more frequent extrapulmonary involvements and tubercle bacilli were rarely isolated from dialysis patients. We inves tigated cell mediated immunity in dialysis patients. The data indicated that dialysis patients have lymphopenia, decreased reaction of PPD, alteration of T cell subset and decreased T cell activity. The experience suggests that patients on dialysis have decreased immunologic host defence and have a greater chance of contracting tuberculosis infection.View full abstractDownload PDF (722K) -
Kazuhiko KAMEDA, Yutaka UEDA, Junko OTSUKA, Nobu KUCHII, Fujiko HORII1985 Volume 60 Issue 2 Pages 59-64
Published: February 15, 1985
Released on J-STAGE: May 24, 2011
JOURNAL FREE ACCESSTuberculosis of lymph nodes is varialbe in its response to treatment. Nodes may enlarge, erupt or form abscesses even during the time of chemotherapy.
In order to think out the optimal duration of treatment for cervical lymph nodes tuberculosis, 75 cases registered as cervical lymph nodes tuberculosis in 11 health centers at the end of the year 1982 were studied.
Sixty out of 75 (80%) were female and the majority of them were aged from 30 to 59 (72%). Thirty-four (45.3%) were diagnosed as cervical lymph nodes tuberculosis by histological examination of biopsied materials, 5 (6.7%) by confirmation of tubercle bacilli from lymphnodes or discharging pus, 9 (12%) by judgement as relapse according to their previous histories, and remaining 27 (36%) by clinical experiences of their doctors.
All cases had received various kinds of chemotherapy for 6 to more than 24 months. Surgical treatment was given for 3 cases among them.
In 3 cases out of 56 assessed through the post-treatment following up for one to five years, the node had become enlarged again after the finish of initial treatment and retreatment was accordingly required.
Among these 3 relapsed cases, 2 received the regimen including RFP for only 6 months and one with INH alone for 12 months. No relapse case was found in the group that received chemotherapy for more than 12 months.
Thus, according to our observation, treatment for the patients with cervical lymph node tuberculosis could be considered to be made in such a way that chemotherapy including REP should be given at least for 12 months and surgical dissection of node is no longer required except the case of lymph node biopsy for diagnostic purposes in modern mangement.View full abstractDownload PDF (667K) -
Hiroshi HAYAKAWA, Kingo CHIDA, Atsuhiko SATO1985 Volume 60 Issue 2 Pages 65-75
Published: February 15, 1985
Released on J-STAGE: May 24, 2011
JOURNAL FREE ACCESSTo investigate the role of bronchus-associated lymphoid tissue (BALT) in delayed-type hypersensitive reaction of the lung, we examined light microscopic findings of the lung and BALT in both normal rabbits and rabbits sensitized intravenously (IV), subcutaneously (SC), and intratracheally (IT) with heat-killed bacillus Calmette-Guerin (BCG).
The rabbits were divided into 5 groups according to the route of sensitization as follows: nonsensitized control group, primary immune response group (IV group), and secondary immune response groups (SC→IV, IV→IV, IV→IT group).
The following results were obtained.
1) BALT in normal rabbits was seen along the air way from main bronchus to bronchioles. BALT was divisible into 4 different areas: lymphoepithelial layer (LE), dome area (DA), follicular area (FA), and parafollicular area (PFA). LE was nonciliated epithelia, and devoid of mucous goblet cells. Massive infiltration of small lymphocytes could be seen, and there was also a slight degree of infiltration of macrophages and plasma cells in LE. FA had characteristics of B cell zone, and postcapillary venules with high endothelium could befound in PFA.
2) Alveolitis and epithelioid cell granulomas were seen in the lungs of all BCG-sensitized groups. The rabbits of IV→IV group developed most extensive granulomatous response in the lungs. There was marked accumulation of pyroninophilic lymphocytes and plasma cells around the granulomas and within the alveolar septa.
3) In the BALT of the secondarily IT sensitized group (IV→IT group), 2 days after secondary sensitization an acid fast organism could be found within a large sized mononuclear cell of LE. In the BALT of the IV sensitized groups (IV, SC→IV, IV→IV group), acid fast organisms could not be seen, but epithelioid cell granulomas could be found.
4) In the course of granulomatous response in the lungs induced by the BCG-sensitization, the number of BALT with FA decreased 2-4 days after secondary IV or IT sensitization in the secondary immune response groups and after primary IV sensitization in the primary immune response group, and then recovered gradually. In LE and DA the number of pyroninophilic lymphocytes and plasma cells increased.
The above results suggest that BALT may induce the local immune response in the lung by uptake of antigen and control the production of immunoglobulins in FA, which may modify the delayed-type hypersensitive reaction in the lung.View full abstractDownload PDF (7428K) -
Especially Emphasis on Its Pathogenesis and Management against Stenosis of TracheaSeiyu HIRATA1985 Volume 60 Issue 2 Pages 77-82
Published: February 15, 1985
Released on J-STAGE: May 24, 2011
JOURNAL FREE ACCESSA case of severe laryngo-tracheo-bronchial tuberculosis of a 46-year-old male caused by contugious infection from a small radiological stable foci located at the left S1+2 C region was reported.
On the way of the chemotherapy, tracheotomy and then dilatation of the trachea by insertion of various size of tracheal tubes-were taken in succession for stenosis of the trachea secondary to antituberculous medication. After the patient's airway was secured by above mentioned manuvers, atelectatic left lung caused by obstruction of the left main bronchus was resected at the 180th hospital day. Finally, respiratory function of the patient was greatly improved and now patient is able to act nearly normal 8 months later since initiation of the treatment.
Both the effectiveness of dilation for tracheal stenosis and possibility to cause the severe tracheo-bronchial tuberculosis from small radiological stable faci are stressed.View full abstractDownload PDF (4410K) -
Rinzo SOEJIMA, Atsuo MIKATA1985 Volume 60 Issue 2 Pages 83-104
Published: February 15, 1985
Released on J-STAGE: May 24, 2011
JOURNAL FREE ACCESSDownload PDF (7148K) -
1985 Volume 60 Issue 2 Pages e1
Published: 1985
Released on J-STAGE: May 24, 2011
JOURNAL FREE ACCESSDownload PDF (24K)
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