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Volume 62, Issue 8
Displaying 1-9 of 9 articles from this issue
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Yo TAJIMA, Rokuro IZUCHI, Tsuyoshi TEZUKA, Akira NAKANO, Yoshihiko MAT ...1987 Volume 62 Issue 8 Pages 395-401
Published: August 15, 1987
Released on J-STAGE: May 24, 2011
JOURNAL FREE ACCESSThirty-two cases of Atypical Mycobacteriosis (AM) were studied clinico-pathologically. The results were as follows.
1) Of 32 patients, 18 died due to AM itself and the remaining 14 cases due to other diseases such as cancer, interstitial pneumonia and others.
2) In these 18 patients, the enlargement of cavities, the extension of lesions, and the abundant discharge of bacilli continued until their death, and in 16 cases the cause of death was AM-pneumonia. The duration from the onset to death was from 5 years to 10 years; in 13 patients it was less than 5 years and in the remaining 5 cases, 8 to 10 years. Thirteen patients out of 18 were female.
3) Histologically, productive lesions were fewer in the cases of AM than those of pulmonary tuberculosis. In general, characteristics of the lesions of AM were exudative or proliferative, and the pneumonia has a lesser tendency to give rise to caseous necrosis compared with tuberculosis.View full abstractDownload PDF (1851K) -
Michio TSUKAMURA, Satoshi ICHIYAMA, Takuya MIYACHI1987 Volume 62 Issue 8 Pages 403-408
Published: August 15, 1987
Released on J-STAGE: May 24, 2011
JOURNAL FREE ACCESSOf more than 200 patients with lung disease due to Mycobacterium avium complex treated in this hospital in a period of 20 years, 124 patients with the following background factors were the subjects of observation: (1) previously untreated by antituberculosis agents; (2) the period of observation more than 9 months; (3) patients with new cavitary lesion in the roentgenographic picture; (4) the extent of disease not more than two lobes; (5) twice or more isolations of the M. avium complex from sputum specimens by monthly sputa examination. Negative conversion of sputum culture was defined as continuous negative cultures for a period of six months or more by monthly sputa examination. The negative conversion rate in each regimen used initially for treatment was compared by the x2-test. Regarding the patients treated by INH alone or INH+PAS (+PZA) as the control group, the patients who were treated by the regimens RFP+INH+SM or RFP+INH+EVM, showed a statistically significantly higher negative conversion rate. The patients who were treated by other regimens, including the regimen RFP+INH+EB, did not show such a significant difference. In conclusion, the first retrospective study of the treatment of M. avium complex disease revealed that combined regimens RFP+SM or RFP+EVM were really effective in the treatment of this disease.View full abstractDownload PDF (788K) -
Aya HAYASHI, Keiichi NAGAO, Hiroko UCHIYAMA, Takayuki KURIYAMA, Akimit ...1987 Volume 62 Issue 8 Pages 409-417
Published: August 15, 1987
Released on J-STAGE: May 24, 2011
JOURNAL FREE ACCESSBy analyzing the data from actual screening work performed by our group, we have given some considerations to perform mass screening for both tuberculosis and lung cancer more efficiently. The results were as follows
1. On the basis of radiophotography, the detailed examinations were considered necessary in 5, 612 subjects, which were 1.52% of the 363, 608 screened.
2. Detection of Tuberculosis
The detailed examination or direct radiography revealed that only 83 subjects had tuberculosis which was classified as “requiring medical treatment”; the remaining majority being supposed to need no treatment.
The rate of detection of tuberculosis “requiring medical treatment” was high in males aged 50 years or more.
Less than half of these detected cases were actually registered as patients, and most of them were 50 years old or more, and quite a few had a history of tuberculosis.
When the patients who were actually treated for tuberculosis are taken as the numerator, the rate of detection is as low as 0.0096%.
3. Detection4 of Lung Cancer
Among 130 subjects which were considered to have lung tumor on the basis of direct radiography, a confirmed diagnosis of lung cancer was made in 62 patients, and the rate of detection is 0.017%.
The detection rate of lung cancer was high in males aged 40 years or more, and in females aged 50 years or more.
Adenocarcinomas were the most common, followed by epidermoid cancers.
The primary lung cancer was surgically removed in 63% of the patients, and 39% of those cases were stage 1.
Eleven percent of those patients with lung cancer had actually undergone a detailed examination in the past, without confirmed diagnosis at that time. That failure was attributed to inadequacy of the detailed examination.
From the facts stated above, the following ideas were proposed: exclusion of persons aged younger than 40 years; comparison of radiophotographs with the earlier ones; omission of radiophotographs in cases with previously known findings of tuberculosis and separate handling of subjects with a history of tuberculosis; double-checking of direct radiographs; improvement of the contents of the detailed examination; public education and consultation after the screening; etc.View full abstractDownload PDF (1231K) -
Kenya HIURA, Hozumi YAMADA, Tsuneko YAMAGUCHI, Hideaki KANEGAE, Osamu ...1987 Volume 62 Issue 8 Pages 419-422
Published: August 15, 1987
Released on J-STAGE: May 24, 2011
JOURNAL FREE ACCESSPulmonary lesions of tuberculosis were detected in 16 out of 390 autopsy cases in Saga Medical School from October 1981 to November 1985. Eight of 16 patients demonstrated pathologically or bacteriologically active pulmonary tuberculosis.
The chest roentgenogram of these active tuberculosis patients showed diffuse miliary nodules in 4 patients, infiltration with a cavity in one and fibrotic lesions with or without cavitary lesions in 3 patients. The underlying diseases of these patients were lung cancer (No.6, 7, 8), stomach cancer (No.5), hepatoma (No.2), progressive systemic sclerosis (No.1), polyarteritis (No.4), and malignant lymphoma (No.3). Miliary tuberculosis was found in 4 patients who had received steroid therapy and/or anticancer chemotherapy, and two of them were also complicated diabetes mellitus. On the other hand, a localized pathological or bacteriological recurrence of pulmonary tuberculosis were detected in 4 patients who had been suffered from far advanced cancer.
This study suggests pulmonary tuberculosis in compromised hosts showed two different types, a systemic dissemination or a localized recurrence pathologically or bacteriologically. We emphasize that evaluation of chest roentgenogram should be done carefully and a repeated sputum culture examination is also needed in compromised hosts to find out complicated active pulmonary tuberculosis.View full abstractDownload PDF (616K) -
[in Japanese]1987 Volume 62 Issue 8 Pages 423-425
Published: August 15, 1987
Released on J-STAGE: May 24, 2011
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[in Japanese]1987 Volume 62 Issue 8 Pages 426-427
Published: August 15, 1987
Released on J-STAGE: May 24, 2011
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[in Japanese]1987 Volume 62 Issue 8 Pages 428-429
Published: August 15, 1987
Released on J-STAGE: May 24, 2011
JOURNAL FREE ACCESSDownload PDF (281K) -
[in Japanese]1987 Volume 62 Issue 8 Pages 430-431
Published: August 15, 1987
Released on J-STAGE: May 24, 2011
JOURNAL FREE ACCESSDownload PDF (272K) -
[in Japanese]1987 Volume 62 Issue 8 Pages 432-433
Published: August 15, 1987
Released on J-STAGE: May 24, 2011
JOURNAL FREE ACCESSDownload PDF (281K)
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