Kekkaku(Tuberculosis)
Online ISSN : 1884-2410
Print ISSN : 0022-9776
ISSN-L : 0022-9776
Volume 74, Issue 10
Displaying 1-5 of 5 articles from this issue
  • SETTING REFERENCE VALUE
    Toshio KISHIMOTO, Osamu MORIYA, Jun-ichi NAKAMURA, Toshiharu MATSUSHIM ...
    1999 Volume 74 Issue 10 Pages 701-706
    Published: October 15, 1999
    Released on J-STAGE: May 24, 2011
    JOURNAL FREE ACCESS
    The determiner TBGL antibody developed by Kyowa-Medex co., ltd. is a new serodiagnostic kit for tuberculosis. To set cut-off point suitable for the kit, TBGL antibody titer of serum from healthy subjects were analyzed in relation to age, sex, previous and family history on tuberculosis. Based on results of healthy subjects, cut-off point was set by using several analytical methods. We propose 2U/ml as a cut-off point for screening of patients with tuberculosis considering the diagnostic efficiency by receiver operating characteristics (ROC) curve analysis and 4U/ml for diagnosis of tuberculosis, which was determined by parametric method considering its specificity.
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  • Chiyoji ABE, Kazue HIRANO, Masako WADA, Eiro TSUBURA, Masaaki YAMANAKA ...
    1999 Volume 74 Issue 10 Pages 707-713
    Published: October 15, 1999
    Released on J-STAGE: May 24, 2011
    JOURNAL FREE ACCESS
    The rate of recovery and the mean time to detection of mycobacteria in clinical specimens were determined in a newly-developed MB Redox system based on liquid medium, and the results were compared with those of MGIT and 2 % Ogawa egg media. From 587 sputum specimens processed, totally 203 mycobacterial isolates were detected, of which 177 (87.2%) with MB Redox, 185 (91.1%) with MGIT and 133 (65.6%) with 2 % Ogawa medium. The difference in the percentages of positive cultures between either of the two liquid media and 2 % Ogawa medium was significant (p<0.0001). The mean time to detection of the Mycobacterium tuberculosis complex was 17.5 days with MB Redox, 18.7 days with MGIT, and 26.2 days with 2 % Ogawa medium. The contamination rates were 1.5, 1.7, and 4.1 % for MB Redox, MGIT, and 2% Ogawa medium, respectively. In conclusion, both MB Redox and MGIT systems, based on liquid medium, are more efficient than 2 % Ogawa medium for the recovery of mycobacteria in clinical specimens.
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  • Yoshihiro KOBASHI, Niro OKIMOTO, Rinzo SOEJIMA
    1999 Volume 74 Issue 10 Pages 715-719
    Published: October 15, 1999
    Released on J-STAGE: May 24, 2011
    JOURNAL FREE ACCESS
    A 49-year-old male was admitted to our hospital complaining of cough and general fatigue. There was nothing unusual about his past history, and he has been healthy. On admission, a chest roentogenogram revealed an infiltrative shadow with a cavity in the left middle and lower fields. Because the acid fast staining of a bronchoscopic specimen was positive for mycobacteria, he was transferred to another hospital to be treated as pulmonary tuberculosis. Culture tests of multiple specimens were positive, and were identified as Mycobacterium szulgai, and the case was diagnosed as pulmonary atypical mycobacteriosis caused by M. szulgai. He was treated with isoniazid, rifampicin and ethambutol daily, but because of side effects, such as drug eruptions, all drugs were stopped. However, his clinical symptoms and infiltration shadow improved gradually.
    We described a rare case of pulmonary disease with Mycobacterium szulgai infection appearing in a healthy male without underlying diseases.
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  • Atsuhiko TADA, Shin KAWAHARA, Naokatsu HORITA, Akihide HORIBA, Akihiko ...
    1999 Volume 74 Issue 10 Pages 721-724
    Published: October 15, 1999
    Released on J-STAGE: May 24, 2011
    JOURNAL FREE ACCESS
    A 84-year-old woman presented with chronic febrile illness and anorexia from June 1998. She was diagnosed as pulmonary tuberculosis and was admitted to our hospital in August 1998. Her sputum smear was Gaffky 2, and the type of chest radiograph was bIII3. By family contact examination in August 1998, chest radiological examinations of her husband, a 86-year-old man, showed consolidation in middle lobe, right pleural effusion and two calcified mediastinal lymphnodes. He was diagnosed as pulmonary tuberculosis complicated with pleurisy. He had poor controlled diabetes mellitus. Tubercle bacilli isolated from their sputa showed the same pattern in restriction fragment length polymorphism analysis. Pulmonary tuberculosis of the husband was considered to be caused by exogenous reinfection.
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  • Tsuyoshi OGURA, Shigeru KOHNO
    1999 Volume 74 Issue 10 Pages 725-766
    Published: October 15, 1999
    Released on J-STAGE: May 24, 2011
    JOURNAL FREE ACCESS
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