Kekkaku(Tuberculosis)
Online ISSN : 1884-2410
Print ISSN : 0022-9776
ISSN-L : 0022-9776
Volume 80, Issue 12
Displaying 1-7 of 7 articles from this issue
  • Naohiko INASE, Shinichirou TOMINAGA, Makito YASUI, Yoshikazu TSUKADA, ...
    2005 Volume 80 Issue 12 Pages 731-734
    Published: 2005
    Released on J-STAGE: May 24, 2011
    JOURNAL FREE ACCESS
    [Purpose] We examined the usefulness of adenosine deaminase 2 (ADA2) in the diagnosis of tuberculous pleuritis.
    [Subjects] A hundred cases, 78 male and 22 female, with pleural effusion were examined. With regard to pleural effusion, 18 cases were transudate and 82 cases (9 tuberculous pleuritis, 27 lung cancer, 8 mesothelioma, 5 malignant diseases except lung cancer and mesothelioma, 5 benign asbestos pleurisy, 10 empyema, 10 parapneumonic effusion, one SLE, one parasitic infection, and 6 undetermined etiology) were exudates. The last 6 cases with unknown origin were excluded in this study.
    [Results] Pleural adenosine deaminase (ADA) was 90.4 ± 22.4 U/l (mean ± SD) and pleural ADA2 was 80.4 ± 21.9 U/l in tuberculous pleuritis, both were significantly higher than those in non-tuberculous exudates (p < 0.001). In the diagnosis of tuberculous pleuritis, pleural ADA showed 100%sensitivity and 88% specificity, whereas pleural ADA2 showed 100% sensitivity and 91 % specificity.
    [Conclusion] Pleural ADA2 is useful in the diagnosis of tuberculous pleuritis, which has similar sensitivity and a little better specificity compared with pleural ADA.
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  • Kunihiko ITO, Akio AONO, Takashi YOSHIYAMA, Masako WADA, Hideo OGATA
    2005 Volume 80 Issue 12 Pages 735-741
    Published: 2005
    Released on J-STAGE: May 24, 2011
    JOURNAL FREE ACCESS
    [Purpose] Investigation on the influence of early start of chemotherapy on the results of sputum smear and culture (Ogawa medium and BACTEC MGIT960).
    [Object and Method] Retrospec tive study for tubercle bacilli positive pulmonary tuberculosis cases in our hospital.
    [Result] Starting chemotherapy before the com pletion of pretreatment sputum examination was found to have no adverse effect on smear positive rate and smear positive grade (246 cases), culture contamination rate on Ogawa medium and BACTEC MGIT960 (1128 sputums), culture positive rate and culture positive grade/time to confirm positive on Ogawa medium (245 cases), and culture positive rate on BACTEC MGIT960 (239 cases). Time to confirm positive on BACTEC MGIT960 was slightly, but significantly prolong ed (1.16days delay in cases with 1-3 days chemotherapy [228 cases], and 4.01 days delay in cases with 4-6 days chemotherapy [59 cases] ).
    [Conclu sion] Influence of early start of chemotherapy on the results of sputum smear and culture is minor. In most of bacilli positive pulmonary tuberculosis cases chemotherapy can be started before the completion of pretreatment sputum examination.
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  • Akira SHIMOUCHI, Shozaburo KONISHI, Takashi TANAKA
    2005 Volume 80 Issue 12 Pages 743-747
    Published: 2005
    Released on J-STAGE: May 24, 2011
    JOURNAL FREE ACCESS
    [Purpose] To ascertain nosocomial tuberculosis (TB) infection control practice in hospitals in Osaka City.
    [Method] A questionnaire was distributed in the o rientation meeting and collected at the occasion of medical inspection in all 196 hospitals in Osaka City in 2003.
    [Results] TB patients were d iagnosed in about half of hospitals in the past 3 years. Basic TB infection control measures were taken in the majority of hospitals; such as chest X-ray screening for all inpatients, health check for employees, tuberculin skin test (TST) for newly employed staff, and nomination of a person in charge of TB infection control. Control measures were practiced more often in hospitals where TB patients were diagnosed, such as “fiberoptic bronchoscopy is to be conducted last in the working hours to avoid contamination of TB bacilli in a room, ”“TST (including two-step method) for all newly employed staff, ”“Staff wear N95 mask when they deal with TB patients/suspects, ” and the differences were statistically significant.
    [Discussion] It is necessar y in hospitals in Osaka City to strengthen nosocomial TB infection control as TB patients were diagnosed in about half of hospitals in the past 3 years. Low cost infection control measures were undertaken more often among hospitals where TB patients were diagnosed. Introduction of high cost equipment or improvement of facilities should be considered in hospitals of high TB risk. Guidelines formulated based on analysis of the survey should facilitate all hospitals to introduce at least low cost effective tuberculosis infection control measures.
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  • 2005 Volume 80 Issue 12 Pages 749-752
    Published: 2005
    Released on J-STAGE: May 24, 2011
    JOURNAL FREE ACCESS
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  • 2005 Volume 80 Issue 12 Pages 753-771
    Published: 2005
    Released on J-STAGE: May 24, 2011
    JOURNAL FREE ACCESS
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  • 2005 Volume 80 Issue 12 Pages 773-784
    Published: 2005
    Released on J-STAGE: May 24, 2011
    JOURNAL FREE ACCESS
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  • 2005 Volume 80 Issue 12 Pages 785
    Published: 2005
    Released on J-STAGE: May 24, 2011
    JOURNAL FREE ACCESS
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