Juntendo Medical Journal
Online ISSN : 2188-2134
Print ISSN : 0022-6769
ISSN-L : 0022-6769
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Volume 42, Issue 3
Displaying 1-24 of 24 articles from this issue
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Contents
  • Reference values for laboratory hematology tests using the automated hematology analyzer system COULTER STKS
    Part1. A study on hematological reference intervals for erythrocyte count, hemoglobin value, hematocrit and other erythrocyte parameters (MCV ·MCH ·MCHC and RDW)
    YOKO TABE, NAOTAKE SATO, KAZUNORI MIYAKE
    1996 Volume 42 Issue 3 Pages 342-348
    Published: November 15, 1996
    Released on J-STAGE: November 18, 2014
    DOIhttps://doi.org/10.14789/pjmj.42.342
    JOURNAL FREE ACCESS
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    Hematological reference intervals were established by using COULTER STKS (automatic blood cell counter and cell analyzer based on flow system). For establishment of reference intervals, 529 healthy samples were obtained from 336 males and 193 females between 18 and 67 years. Sex dependent differences in the reference intervals of RBC, Hb, PCV and MCV were calculated. No sex difference was observed in the reference intervals of MCV, MCH and RDW. In the statistical treatment, adjustment by the XP-Type variable transformation was often necessary to obtain the normal distribution. Because of the strong deviation in the distribution pattern, the reference intervals for RDW, MCH, and MCHC were generated by a non-parametric (percentile) method instead of parametric method.
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  • Reference values for laboratory hematology tests using the automated hematology analyzer system COULTER STKS
    Part 2; A study on hematological reference intervals for white blood cell, platelet count, plateletcrit, mean platelet volume and platelet distribution width, including a study of platelet measurements
    YOKO TABE, NAOTAKE SATO, KAZUNORI MIYAKE
    1996 Volume 42 Issue 3 Pages 349-356
    Published: November 15, 1996
    Released on J-STAGE: November 18, 2014
    DOIhttps://doi.org/10.14789/pjmj.42.349
    JOURNAL FREE ACCESS
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    Hematological reference intervals were established by using COULTER STKS (automatic blood cell counter and cell analyzer based on flow ststem). For establishment of reference intervals, 529 healthy samples were sobtaired from 336 males and 193 females between 18 and 67 years. Sex depengent differences in the reference intervals of WBC were calculated. No sex difference was observed in the reference intervals of PLT, Pct, MPV and PDW. In the statistical treatment adjustment by the XP-Type variable transformation was often necessary to obtain the normal distribution. The reference intervals for PDW were generated by the non-parametric (percentile) method instead of the parametric method because of the strong deviation in the distribution pattern. Some differences were observed between these reference values and the previous ones. The differences supposedly depend on the reference individuals and method of laboratory tests and/or amount of data. The findings suggest the adequency of resetting the reference intervals. Automated hematology analyzers provide some indexes of platelet measurements such as mean platelet volume (MPV) and platelet distribution width (PDW). MPV distribution is increased in association with the decrease in platelets (PLT). These new variables may be useful in the initial classification of platelet disorders and other disease.
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  • A clinical and electroencephalographic studies of parietal midline-spikes (Pz spike)
    KYOKO WATANABE, KEIICHI TAKAHASHI
    1996 Volume 42 Issue 3 Pages 357-367
    Published: November 15, 1996
    Released on J-STAGE: November 18, 2014
    DOIhttps://doi.org/10.14789/pjmj.42.357
    JOURNAL FREE ACCESS
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    Negative spikes and sharp waves with maximum amplitude (Pz spike) are sometimes observed exclusively on the parietal midline on EEG of sleeping chidren. We studied 115 cases showing Pz spikes (67 boys and 48 girls) and compared their ages, clinical features, EEG courses and EEG of their siblings. In eighty-nine (77%) of 115 cases, onset of Pz spike was distributed between three to seven years of age with the highest incidence (25 cases) at 4 years of age. These results suggest that the appearance of Pz spikes may be age-related. The underlying diseases in these 115 cases showing Pz spikes were febrile convulsions in 43 cases (37%) and epilepsy in 34 cases (30%). There were also non-convulsive disorders, such as 16 cases of autonomic symptoms and 15 cases of head trauma. However, it is considered that Pz spikes may be independent of clinical seizures because 65% of the cases involving febrile convulsions or epilepsy manifested 5 or fewer seizures. In 64 (81%) of 79 cases that were followed by EEG for 2years or more. Pz spikes disappeared by 15 years of age or earlier in 97% of the cases. EEG was also exanined 18 siblings in 14 families with children showing Pz spikes. Pz spikes were found in the siblings belonging to 6 families. The age at onset of Pz spikes was almost the same between the patients and the siblings. We think that genetic factors may be involved the appearance of Pz spikes.
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  • Analysis of proliferating potential by argyrophilic nucleolar organizer regions (AgNORs) and proliferating cell nuclear antigen (PCNA) staining in experimental pancreatic ductal carcinoma in dogs.
    -Study of the incipient phase of pancreatic ductal carcinoma-
    KEI NAKAMURA
    1996 Volume 42 Issue 3 Pages 368-377
    Published: November 15, 1996
    Released on J-STAGE: November 18, 2014
    DOIhttps://doi.org/10.14789/pjmj.42.368
    JOURNAL FREE ACCESS
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    Proliferating potential of the incipient phase of pancreatic ductal carcinoma in 9 dogs were studied by AgNORs and PCNA staining. Various pancreatic lesions including intraductal carcinoma, dysplasia and papillary hyperplasia, were found more fregvently in the intraductal administration group than in the group receiving a total dose of 350mg N-ethyl-N'-nitro-N-nitrosoguanidine (ENNG). However, only hyperplasia was found less often in the intraductal administration group compared to that in the group receiving a total dose of 130mg ENNG. There were significant differences between the two group. AgNORs score and RCNA positive rate increased as the degree of atypia increased. AgNORs score and PCNA positive rate increased in a stepwise manner in pancreatic ductal lesions during the process of pancreatic ductal carcinogenesis. There were significant differences between two processes. The AgNORs score correlated well with the PCNA positive rate. The results suggested that dysplasia is important during incipient phase of experimental pancreatic ductal carcinoma in dogs.
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  • Life style and obesity in 3-year-old children in shanghai, China
    FANGFANG YE, LING WANG, MING XU, TAKASHI MUTO
    1996 Volume 42 Issue 3 Pages 378-386
    Published: November 15, 1996
    Released on J-STAGE: November 18, 2014
    DOIhttps://doi.org/10.14789/pjmj.42.378
    JOURNAL FREE ACCESS
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    In the first part of a prospective cohort research project studying prevention of adult diseases from childhood, we investigated 1,007 preschool children born between June 1, 1990 and May 31, 1991, who live in Shanghai, China. The results of this study were as follows: the average height of these children was 98.6±4.5 (cm); the average weight was 15.0±1.8 (kg); the coefficient of correlation between the obesity index of the children and their father's and mother's BMI (Body Mass Index) was 0.16 and 0.15, respectively. These valves were significant, despite being relatively low. Almost all of the children studied (99.5%) had fixed meal-times ; 68% slept more than 10 hours a day ; 74% had bowel movements once a day ; 96% had a regular defecation time ; these practices and other life style factors in these children were well established. A positive relationship was identified between the amount of milk and other dairy products consumed and the obesity index, suggesting that obesity in children is influenced by life style.
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