Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
Volume 44 , Issue 4
Showing 1-36 articles out of 36 articles from the selected issue
PRESIDENTIAL LECTURE
EDITORIALS
ORIGINAL ARTICLE
  • Ryuji SAKAKIBARA, Tomoyuki UCHIYAMA, Zhi LIU, Tatsuya YAMAMOTO, Takash ...
    2005 Volume 44 Issue 4 Pages 281-284
    Published: 2005
    Released: May 17, 2005
    JOURNALS OPEN ACCESS
    Objective Nocturia is a common reason for interrupted sleep in post-stroke patients. These patients often have neurogenic bladder overactivity. However, little is known about the possible contribution of nocturnal polyuria in the patients.
    Methods We measured the number of nocturia, the circadian plasma arginine vasopressin (AVP) level and urinary excretion in 4 patients with stroke.
    Results All patients had nocturnal urinary frequency (three times in one and twice in 3). All patients were revealed to have nocturnal polyuria, and the ratio of nocturnal urinary output to 24 hour volume ranged from 36% to 63%. Measurement of daily plasma AVP variation showed that all patients lost normal nocturnal rise of the plasma AVP concentration. Two patients were successfully treated with 5 μg of intranasal desmopressin once a night, a potent analogue of AVP, without hypertension particularly in the night, signs of congestive cardiac failure or any electrolyte abnormality such as hyponatremia.
    Conclusion Our post-stroke patients had nocturnal polyuria with abnormal circadian rhythm of plasma AVP secretion. Desmopressin reduced nocturnal waking in urination. It also ameliorated nocturnal dehydration that might trigger a stroke recurrence in the patients.
    Download PDF (46K)
CASE REPORTS
SHORT COMMUNICATION
PICTURES IN CLINICAL MEDICINE
I. Therapeutic Strategy for Acute Stroke -Prologue for an Epoch of Brain Attack-
II. Appropriate Use of Antibiotics and Guideline(s) for This Purpose
III. New Aspects of Renal Diseases -From Urine Checkup to Kidney Transplantation-
feedback
Top