This investigation was designed to determine the role of the endocochlear potential (EP) in the electrical phenomena of the inner ear.
EP, cochlear microphonics (CM) and summating potential (SP) were measured in the guinea pig cochlea both during and after anoxia, and after intravenous administration of diuretic (furosemide), respectively, to observe the relationship of these electrical phenomena in the inner ear.
Under both conditions, EP dropped rapidly from its high positive value to a negative value.
After the potential reached a negative maximum, it slowly returned to its first high positive level.
But the pattern of changes in EP, CM and SP under anoxia and administration of furosemide was quite different, that is, during and after anoxia, EP varied its value proportional to CM. On the other hand, under latter condition, EP recovered long after CM reached the first value.
Conclusively, these facts seemed to explain EP was not merely the amplifier of CM.
抄録全体を表示