Journal of the Japan Diabetes Society
Online ISSN : 1881-588X
Print ISSN : 0021-437X
ISSN-L : 0021-437X
Volume 53, Issue 2
Displaying 1-10 of 10 articles from this issue
Feature: Diabetic Neuropathy Up-to-date
Original Articles
  • Akihiro Yoshida, Masaaki Kouwaki, Masaki Makino, Kentarou Fujiwara, Mi ...
    2010 Volume 53 Issue 2 Pages 90-95
    Published: 2010
    Released on J-STAGE: April 26, 2010
    JOURNAL FREE ACCESS
    Vascular lesions accompanying diabetes mellitus are closely related to atherosclerosis onset and progression, so we studied the relationship between the cardioankle vascular index (CAVI) and of NT-proBNP and metabolic syndrome and of atherosclerosis risk markers. We divided the diabetic retinopathy of 69 subjects with type 2 diabetes mellitus into three groups-normal (N), simple retinopathy (S), and proliferative retinopathy (P). The CAVI, a stiffness index, and NT-proBNP, a cardiac function index, increased as retinopathy progressed and NT-proBNP correlated significantly with R-CAVI (r=0.401, p=0.0006) and L-CAVI (r=0.450, p<0.0001). Our results suggest that the increase in CAVI and NT-proBNP in subjects with diabetic retinopathy is a useful index of atherosclerosis progression and cardiovascular function.
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  • Ikuo Kanamoto, Yutaka Inoue, Tadashi Moriuchi, Yoshie Yamada, Hisako I ...
    2010 Volume 53 Issue 2 Pages 96-101
    Published: 2010
    Released on J-STAGE: April 26, 2010
    JOURNAL FREE ACCESS
    Results of tests in 10 healthy adults to determine how postprandial glucose and serum insulin profiles vary after the vegetable salad intake sequence of cabbage, olive oil, and vinegar was changed with rice showed that ingesting salad before rice significantly decreased incremental plasma glucose (ΔC) 20, 30, and 45 minutes postprandially (p<0.01). The time until maximum plasma glucose (ΔCmax) was reached was delayed 40 minutes (p<0.01), compared to when salad was ingested after rice. ΔCmax decreased by a mean 21% and the incremental area under the curve from 0 to 120 minutes postprandially decreased by a mean 39%. Serum insulin varied parallel with plasma glucose, suggesting that postprandial insulin secretion is controlled. Ingesting salad before rice effectively suppresses postprandial plasma glucose.
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Case Reports
Co-medicals; Original Article
  • Saeko Imai, Mikuko Matsuda, Saori Fujimoto, Shuichi Miyatani, Goji Has ...
    2010 Volume 53 Issue 2 Pages 112-115
    Published: 2010
    Released on J-STAGE: April 26, 2010
    JOURNAL FREE ACCESS
    Postprandial hyperglycemia is associated with increased risk for macrovascular disease. We studied the effects of eating "vegetables before carbohydrates" on postprandial plasma glucose in outpatients with type 2 diabetes mellitus (T2DM). We conducted a randomized crossover study in 15 subjects with T2DM patients controlled by diet and having the following profiles age 61.7±11.6 yrs, male/female ratio: 7/8, BMI 24.7±4.3, HbA1c 6.0±0.6%, years of DM duration 5.3±8.8 yrs: mean±SD. Subjects ate test meals consisting of white rice and vegetable salad, eating either "carbohydrates before vegetables" or vice versa for 4 weeks. Plasma glucose and serum insulin were evaluated at 0, 30, 60, and 120 min after each meal. Postprandial plasma glucose in those following the "vegetables before carbohydrates" regimen was reduced at 30 and 60 min compared to the reverse regimen at 217±40 vs 172±31 mg/dl (P<0.01) and 208±56 vs 187±41 mg/dl (P=0.074). Postprandial serum insulin decreased significantly at 30 and 60 min in the "vegetables before rice" regimen at 32.9±20.8 vs 22.3±14.6 μU/ml (P<0.01), 35.4±21.6 vs 24.9±13.4μU/ml (P<0.05). These results suggest that eating vegetables before carbohydrates may be beneficial in preventing subjects with postprandial hyperglycemia and T2DM.
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