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Volume 48, Issue 10
Displaying 1-11 of 11 articles from this issue
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Pathogenesis and Treatment of Diabetes-related Ophthalmologic Complications
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Y. Uchigata2005 Volume 48 Issue 10 Pages 711
Published: 2005
Released on J-STAGE: April 11, 2008
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S. Sato, H. Yamashita2005 Volume 48 Issue 10 Pages 713-716
Published: 2005
Released on J-STAGE: April 11, 2008
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T. Awata2005 Volume 48 Issue 10 Pages 717-719
Published: 2005
Released on J-STAGE: April 11, 2008
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H. Funatsu2005 Volume 48 Issue 10 Pages 721-723
Published: 2005
Released on J-STAGE: April 11, 2008
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S. Kitano2005 Volume 48 Issue 10 Pages 725-728
Published: 2005
Released on J-STAGE: April 11, 2008
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K. Ohta, T. Murata2005 Volume 48 Issue 10 Pages 729-731
Published: 2005
Released on J-STAGE: April 11, 2008
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Original Article
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Shinsuke Nakata, Hiromi Iwahashi, Jungo Terasaki, Hiroyuki Konya, Mei ...2005 Volume 48 Issue 10 Pages 733-738
Published: 2005
Released on J-STAGE: April 11, 2008
JOURNAL FREE ACCESSThe aim of this study was to identify factors affecting the improvement in glycemic control after switching diabetic patients on multiple daily insulin injections (MDI) from regular insulin (R) to a quick-acting insulin analogue (Aspart). Twenty-seven patients (male/female, 15/12 : Type 2/Other type, 10/14/3) on MDI without using glargin were switched from R to Aspart as bolus insulin and followed up for 24 weeks. HbA1c improved in 10 patients, and worsened in 17 patients. Serum C-peptide immunoreactivity (s-CPR) before lunch was significantly higher in the improved group than in the worse group, and all the patients with a s-CPR value below 0.5 ng/ml belonged to the worse group. In addition, the score on the Problem Areas in Diabetes scale (PAID) measuring diabetes-related distress rose significantly in the worse group. The results showed that the s-CPR value before lunch is useful for predicting improvement of glycemic control when switching from R to Aspart and that the diabetes-related distress became worse even with quick-acting insulin unless glycemic control improved.View full abstractDownload PDF (239K)
Case Report
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Takuya Doi, Hiroto Furuta, Masanori Tamai, Hiroko Shimomura, Masato Ko ...2005 Volume 48 Issue 10 Pages 739-744
Published: 2005
Released on J-STAGE: April 11, 2008
JOURNAL FREE ACCESSA 40-year-old type 1 diabetes patient was hospitalized because of a coma secondary to diabetic ketoacidosis (DKA). On the next day, ST elevation was noted in leads II, III, aVF and V5-V6, of the electrocardiogram (ECG), even though his consciousness level had improved and he did not complain of any symptoms of heart disease. The serum creatine phosphokinase (CK) level, which was slightly elevated on admission, rapidly increased to 4,021 U/l, and the troponin T test was positive. Cardiac angiography revealed diffuse hypokinesis of the left ventricle, but no coronary artery stenosis or obstruction. Although the hyperglycemia and hyperkalemia had improved at the time of the ECG change, hypophosphatemia was observed.
These findings suggest that the patient had mild myocardial damage on admission, and that an acute change in electrolyte and metabolism, especially the hypophosphatemia, caused by treatment of the DKA induced further myocardial damage and resulted in the ST elevation.View full abstractDownload PDF (365K) -
T. Sakai, M. Okamoto, A. Yamamoto, M. Onishi, T. Murakami, K. Kasuga, ...2005 Volume 48 Issue 10 Pages 745-749
Published: 2005
Released on J-STAGE: April 11, 2008
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Co-medical
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K. Yamatsu, S. Kumagai, H. Sasaki2005 Volume 48 Issue 10 Pages 751-756
Published: 2005
Released on J-STAGE: April 11, 2008
JOURNAL FREE ACCESS
Report of the Committee
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Shigeki Inomata, Masakazu Haneda, Tatsumi Moriya, Shigehiro Katayama, ...2005 Volume 48 Issue 10 Pages 757-759
Published: 2005
Released on J-STAGE: April 11, 2008
JOURNAL FREE ACCESSThe Diabetic Nephropathy Committee recommends the use of revised criteria for the early diagnosis of diabetic nephropathy in Japan. The new criteria are as follows : 1) Urinary albumin should be determined by immunoassay using a morning spot urine sample in diabetic patients without proteinuria or with dipstick-positive (+1) proteinuria. 2) A urinary albumin-to-creatinine ratio ranging from 30 to 299 mg/gCr in 2 or more of 3 specimens may be diagnosed as microalbuminuria. 3) Two alternatives, i.e. the urinary albumin excretion rate of 30-299 mg/24 hr in 24 hr urine collection and 20-199 μg/min in timed urine collection can be used to detect microalbuminuria. 4) Renal hypertrophy and elevated urinary type IV collagen may indicate the existence of diabetic renal disease. 5) Microalbuminuria originating in nondiabetic diseases should be excluded.View full abstractDownload PDF (196K)
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