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Volume 45, Issue 1
Displaying 1-13 of 13 articles from this issue
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[in Japanese]2002 Volume 45 Issue 1 Pages 1
Published: January 30, 2002
Released on J-STAGE: March 02, 2011
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[in Japanese]2002 Volume 45 Issue 1 Pages 3-4
Published: January 30, 2002
Released on J-STAGE: March 02, 2011
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[in Japanese]2002 Volume 45 Issue 1 Pages 5-7
Published: January 30, 2002
Released on J-STAGE: March 02, 2011
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[in Japanese]2002 Volume 45 Issue 1 Pages 9-11
Published: January 30, 2002
Released on J-STAGE: March 02, 2011
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[in Japanese]2002 Volume 45 Issue 1 Pages 13-15
Published: January 30, 2002
Released on J-STAGE: March 02, 2011
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[in Japanese]2002 Volume 45 Issue 1 Pages 17-19
Published: January 30, 2002
Released on J-STAGE: March 02, 2011
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Kunihiro Ekawa, Keigo Naka, Mariko Miyawaki, Chikato Oki, Tetsuhiro Ka ...2002 Volume 45 Issue 1 Pages 21-26
Published: January 30, 2002
Released on J-STAGE: March 02, 2011
JOURNAL FREE ACCESSWe evaluated 106 patients with type 2 diabetes mellitus and 247 healthy controls between 20 and 69 of age. Rest 12-lead electrocardiograms were recorded to measure corrected QT dispersion (QTcd), defined as the difference between minimum and maximum QT interval corrected using Bazett's formula. Mean QTcd was 47.7±21.5 ms in diabetic patients and 25.3±9.7 ms in healthy controls (mean±SD). In each age group, the mean of QTcd of diabetic patients was significantly greater than that of healthy controls (p<0.05). Since in younger diabetic patients with short duration of diabetes, mean QTcd was significantly greater than for healthy controls in the same age group, we believe that the cardiac muscle is injured by a metabolic disorder even in early diabetes mellitus.Mean QTcd significantly increased in patients with an over 20-year duration of diabetes and in those with retinopathy.With increasing duration of diabetes, QTcd increases with the development of diabetic complications such as retinopathy.View full abstractDownload PDF (1034K) -
[in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...2002 Volume 45 Issue 1 Pages 27-31
Published: January 30, 2002
Released on J-STAGE: March 02, 2011
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Tsutomu Araki, Ryuichiro Soma, Yohei Tofuku2002 Volume 45 Issue 1 Pages 33-38
Published: January 30, 2002
Released on J-STAGE: March 02, 2011
JOURNAL FREE ACCESSA 18-year-old man with chromosomal abnormality and type 2 diabetes mellitus was admitted for fever, cough, and sputum. Laboratory findings showed WBC 16, 200/μl, CRP 23.4 mg/dl, PO2 75.8 mmHg, glu-cose 327 mg/dl, and HbAic 7.3%. Based on chest computed tomography (CT) findings, we diagnosed lung abscess of the left lower lobe and administered insulin and antibiotics (IPM/CS+CLDM). His respiratory status and laboratory data worsened (WBC 23, 800/μl, CRP 31.5 mg/dl, PO2 56.8 mmHg) on day 3 and we diagnosed left thoracic empyema based on chest CT findings, and inserted a chest tube. Although he was treated with antibiotics and chest tube drainage for 4 weeks, purulent effusion from the chest tube persisted, so we undertook surgery on day 40. The postoperative clinical course was good, and the chest tube was removed on day 54. Laboratory findings of diabetes also improved (glucose 100 mg/dl, HbAic 6.2%) at discharge. Smith-Magenis syndrome was finally diagnosed based on the chromosomal abnormality (deletion 17 p 11.2) and characteristic clinical features mental retardation with behavior problems, facial anomalies, and short, broad hands with short fingers.View full abstractDownload PDF (2064K) -
[in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...2002 Volume 45 Issue 1 Pages 39-44
Published: January 30, 2002
Released on J-STAGE: March 02, 2011
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Shizuka Ohnuma, Mariko Higa, Masato Kojima, Kayoko Nomura, Toshiki Ino ...2002 Volume 45 Issue 1 Pages 45-49
Published: January 30, 2002
Released on J-STAGE: March 02, 2011
JOURNAL FREE ACCESSIn a 71-year-old woman admitted for consciousness disturbance, laboratory data on admission showed plasma glucose of 1651mg/dl, blood pH of 7.08 and HCO3- of 6.2mmol/L, and serum CPK and creatinine levels of 26770U/L, and 4.9mg/dl, respectively. A diagnosis of diabetic coma complicated by metabolic acidosis, rhabdomyolysis and acute renal failure was made, and saline infusion and continuous insulin administration were started immediately.Plasma glucose fell progressively, and serum CPK and creatinine decreased gradually. Ten hours after admission, the patient developed diarrhea and bloody stool, and was diagnosed with ischemic colitis after endoscopy indicated an irregular ulcer of the sigmoid colon and rectum. Type 1 diabetes mellitus was diagnosed based on the marked decrease in urinary C-peptide and positive islet cell antibodies (ICA). In addition to arteriosclerosis, hyperglycemia, which increased blood viscosity, may have eventually caused insufficient blood circulation in the bowel, resulting in ischemic colitis.
These noteworthy findings indicate that ischemic colitis associated with diabetic coma should be recognized.View full abstractDownload PDF (1377K) -
Rie Fujita, Akimitsu Takahashi, Hiroaki Sato, Satoshi Ayuzawa, Koichi ...2002 Volume 45 Issue 1 Pages 51-56
Published: January 30, 2002
Released on J-STAGE: March 02, 2011
JOURNAL FREE ACCESSA 71-year-old man with a 5 to 6-year history of poorly controlled type 2 diabetes mellitus was admitted for involuntary movement (hemichorea) of the right upper and lower extremities.Plasma glucose was 456-767mg/dl, and HbA1c 13.8%. Magnetic resonance imaging (MRI) showed hyperintensity on T 1-weighted images in the left putamen and caudate nucleus.Involuntary movements were resolved in l month when plasma glucose was corrected by diet and oral medication. After discharge, hyperglycemia recurred and poor diabetic control persisted. Eight months later, he was readmitted with hyperglycemia, and his plasma glucose was 515mg/dl and HbA1c 12.1%. On the second admission, involuntary movement recurred in the right leg. His diabetic hemichorea-hemiballism was thus a novel diabetic complication.View full abstractDownload PDF (1134K) -
[in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...2002 Volume 45 Issue 1 Pages 57-60
Published: January 30, 2002
Released on J-STAGE: March 02, 2011
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