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Volume 51, Issue 12
Displaying 1-11 of 11 articles from this issue
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Original Article
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Shoichi Akazawa, Yoko Sagara, Masayuki Tojikubo, Tomoko Towatari, Yasu ...2008 Volume 51 Issue 12 Pages 1051-1057
Published: 2008
Released on J-STAGE: May 20, 2009
JOURNAL FREE ACCESSWe measured brain natriuretic peptide (BNP) concentration in an echocardiographic evaluation of 384 type 2 diabetic patients without heart disease or chronic renal failure. BNP concentration was significantly higher in patients with hypertension than in those without and in those with diabetic complications such as diabetic nephropathy, retinopathy and neuropathy than in those without. Multiple regression analysis showed age, systolic and diastolic pressure, LVMI, retinopathy, and female gender to be significantly associated with BNP concentration (R=0.508, p<0.0001, R2=0.258). In hypertensive diabetic patients, BNP concentration was higher in those with “concentric” or “eccentric” left ventricular hypertrophy than in those with a normal pattern.
These results indicate that hypertension and either concentric or eccentric left ventricular hypertrophy in response to it or diastolic dysfunction may elevate BNP concentration and increasing with advancing age in diabetic patients apparently free of heart disease and renal failure.View full abstractDownload PDF (336K)
Case Report
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T. Maruta, C. Ide, A. Watanabe, Y. Sakai, S. Hiramatsu, H. Yoshizumi, ...2008 Volume 51 Issue 12 Pages 1059-1064
Published: 2008
Released on J-STAGE: May 20, 2009
JOURNAL FREE ACCESS -
Kazuya Yoshida, Koji Murao, Toshihiko Ishida2008 Volume 51 Issue 12 Pages 1065-1070
Published: 2008
Released on J-STAGE: May 20, 2009
JOURNAL FREE ACCESSA 45-year-old woman with thirst and vomiting 10 days before admission, followed by consciousness disturbance and brought to the emergency clinic was found to have plasma glucose of 955 mg/dl and HbA1c of 5.9%, together with markedly increased ketone bodies and serum pancreatic exocrine enzymes. Urinary C-peptide was very low, and she had no GAD antibody-all consistent with fulminant type 1 diabetes. Continuous insulin infusion therapy restored consciousness the next day, but she lost consciousness again 3 days after admission due to hypernatremia. She suffered emphysematous cholecystitis 21 days after admission. Ultrasonagraphy and computed tomography showed gas in the gallbladder, necessitating emergency cholecystectomy. Pathological analysis showed full-thickness infarctive necrosis. Emphysematous cholecystitis is a rare condition caused by ischemia of the gallbladder. This case suggests that emphysematous cholecystitis can be caused by dehydration and anorexia with fulminant type 1 diabetes.View full abstractDownload PDF (482K) -
A. Arimura, S. Horinouchi, N. Imamoto, K. Niina, T. Deguchi, K. Arimur ...2008 Volume 51 Issue 12 Pages 1071-1074
Published: 2008
Released on J-STAGE: May 20, 2009
JOURNAL FREE ACCESS -
T. Asano, M. Kawamura, R. Chin, M. Abe, S. Miyazaki, Y. Hirata2008 Volume 51 Issue 12 Pages 1075-1079
Published: 2008
Released on J-STAGE: May 20, 2009
JOURNAL FREE ACCESS -
N. Oda2008 Volume 51 Issue 12 Pages 1081-1085
Published: 2008
Released on J-STAGE: May 20, 2009
JOURNAL FREE ACCESS -
Tomoki Nakano, Yoshimasa Aso, Kohzo Takebayashi, Takaji Takai, Toshihi ...2008 Volume 51 Issue 12 Pages 1087-1092
Published: 2008
Released on J-STAGE: May 20, 2009
JOURNAL FREE ACCESSWe report a rare case of fulminant type 1 diabetes associated with Graves' disease. A 38-year-old woman admitted for diabetic ketoacidosis 2 days after rapid onset had markedly elevated plasma glucose of 793 mg/dl but HbA1c of 5.8%. Islet cell autoantibodies were negative. Serum C peptide had decreased to <0.1 ng/ml and urinary C peptide to 1.0 μg/day. Based on these findings, she was diagnosed with fulminant type 1 diabetes. Tachycardia remained despite fluid and insulin therapy. Thyroid function on day 6 indicated elevated thyroid hormone and positive TSH receptor antibody, yielding a diagnosis of Graves' disease. Class II HLA genotype analysis showed a haplotype with DRB1*0405-DQB1*0401, representing a major type 1 diabetes-susceptible haplotype. The plasma concentration of interferon-inducible protein-10 (IP-10), a T-helper 1-related chemokine, was elevated to 141 pg/ml at onset, and to 143 pg/ml after 6 months of treatment.View full abstractDownload PDF (323K) -
M. Masuzawa, E. Uechi, M. Matsuda, S. Motojima2008 Volume 51 Issue 12 Pages 1093-1098
Published: 2008
Released on J-STAGE: May 20, 2009
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Kenzo Iino, Masanori Iwase, Miwako Oku, Sakae Nohara, Mitsuo Iida2008 Volume 51 Issue 12 Pages 1099-1103
Published: 2008
Released on J-STAGE: May 20, 2009
JOURNAL FREE ACCESSPyomyositis, a pyogenic skeletal muscle infection, once common only in the tropics, is being seen increasingly frequently in temperate climates. The thigh muscles are most often involved, but the paravertebral muscles rarely so. We report three cases of pyomyositis chiefly affecting the paraspinal muscles of diabetic patients and presenting as lumbago.
In case 1, a 49-year-old woman was admitted for low right back pain and fever. In case 2, a 60-year-old man admitted for low back pain and fever developed severe pain after undergoing a local intramuscular anesthetic injection for lumbago. In case 3, a 68-year-old man suffering from alcoholism and admitted for consciousness disturbance had reported continuous lumbago after undergoing left lumbar laminectomy for lumbar spinal canal stenosis. In all three cases, computed tomography (CT) demonstrated lesions with enhanced rims in the erector spine muscle in these cases. The three patients recovered uneventfully after intravenous antibiotics and, in case 1, a psoas muscle incision. Because the pyomyositis risk in diabetic patients may be enhanced, however, injections and other surgical procedures should be undertaken with due caution.View full abstractDownload PDF (487K) -
A. Ihara, M. Kobayashi, H. Aoki, M. Handa2008 Volume 51 Issue 12 Pages 1105-1109
Published: 2008
Released on J-STAGE: May 20, 2009
JOURNAL FREE ACCESS
Co-medical
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H. Ijima, N. Nakamura, S. Ogata, M. Miyano, A. Matsushita, M. Fukunaga ...2008 Volume 51 Issue 12 Pages 1111-1116
Published: 2008
Released on J-STAGE: May 20, 2009
JOURNAL FREE ACCESS
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