Journal of the Japan Diabetes Society
Online ISSN : 1881-588X
Print ISSN : 0021-437X
ISSN-L : 0021-437X
Search
Advanced search
OR
Browse
Search
Volume 14, Issue 5
Displaying 1-11 of 11 articles from this issue
Show all abstracts
    • |<
    • <
    • 1
    • >
    • >|
  • Cortisol Binding Capacity in Plasma of the Patients with Diabetes Mellitus
    Atsuo Kawai, Nobusada Kuzuya
    1971 Volume 14 Issue 5 Pages 271-276
    Published: September 30, 1971
    Released on J-STAGE: August 10, 2011
    DOIhttps://doi.org/10.11213/tonyobyo1958.14.271
    JOURNAL FREE ACCESS
    Show abstractHide abstract
    Cortisol binding capacity (C. B. C.) in plasma was measured in 51 diabetics (32 male, 19 female) and 32 healthy subjects (23 male, 9 female) with the aid of Doe and Seals' method.
    Diabetic group showed a significantly lower C. B. C. values than the healthy group (p<0.01), which was more prominent in male patients.
    In order to explore the cause of such decline in C. B. C. in diabetic patients, various possible factors were correlated with C. B. C.
    No direct relationship was established between C. B. C. levels and plasma cortisol concentrations, fasting blood sugar levels or degree of excess in body weight. Also, there was no tendency that lowering of C. B. C. was predominant among patients with diabetic heredity.
    There was a linear relationship between C. B. C. and serum albumin in the diabetic patients (y=4.05x+13.7, p<0.01). Furthermore, there exhibited a tendency that the more the patients suffered from diabetic complications (nephropathy, retinopathy and neuropathy), the lower C. B. C. as well as serum albumin concentration they had.
    The results of these studies indicate that hypoalbuminemia due to diabetic nephropathy, through an unknown mechanism, may play a leading role in lowering C. B. C. in the diabetic patients. Alternatively, however, there still exists a possibility that inborn impairment of C. B. C. in diabetic patients was accompanied by increment of native free cortisol, which in turn deteriorates the diabetic compications.
    View full abstract
    Download PDF (890K)
  • Five Year's Time-Course Studies on the Changes of Glucose Tolerance
    Cortison-Glucose Tolerance Test in Potential and Latent Diabetic Patients
    Kazuo Katsumata, Isamu Tuchida
    1971 Volume 14 Issue 5 Pages 277-281
    Published: September 30, 1971
    Released on J-STAGE: August 10, 2011
    DOIhttps://doi.org/10.11213/tonyobyo1958.14.277
    JOURNAL FREE ACCESS
    Show abstractHide abstract
    100 g glucose tolerance test (GTT) and cortisonglucose tolerance test (CGTT) were performed on 43 spersons of 2 potential, 3 renale diabetic and 38 latent diabetic patients. GTT and CGTT of 43 persons were ystematically tested during 5 years. Eighteen persons had diabetic relatives, 25 persons had not. The grades of abnormalities of GTT and CGTT were classified to N, L and D, depending on their blood glucose values at 1 and 2 hours after glucose loading.
    The persons who showed L in GTT and L or D in CGTT at the beginning of these experiments became diabetic in 4-5 years more frequently than the persons who showed N in GTT or CGTT at the beginning of experiment. Especially in the cases of L, D type of CGTT, this tendency was apparent regardless to their data in GTT. Considering the changes of GTT in each person during the 5 year's observation, data of GTT was well coincide with that of CGTT.
    Judging from the results of time-course studies on the latent diabetic persons who showed N or L in GTT, they were supposed to have constant metabolic disorders and the considerable possibility to become diabetic if they showed D in CGTT.
    It is recognized that CGTT is very valuable, especially to the cases with N or L in GTT, that is normal or slightly abnormal glucose tolerance.
    View full abstract
    Download PDF (915K)
  • [title in Japanese]
    1971 Volume 14 Issue 5 Pages 282-285
    Published: September 30, 1971
    Released on J-STAGE: August 10, 2011
    DOIhttps://doi.org/10.11213/tonyobyo1958.14.282
    JOURNAL FREE ACCESS
    Download PDF (754K)
  • [title in Japanese]
    1971 Volume 14 Issue 5 Pages 285-287
    Published: September 30, 1971
    Released on J-STAGE: August 10, 2011
    DOIhttps://doi.org/10.11213/tonyobyo1958.14.285
    JOURNAL FREE ACCESS
    Download PDF (575K)
  • [title in Japanese]
    1971 Volume 14 Issue 5 Pages 287-301
    Published: September 30, 1971
    Released on J-STAGE: August 10, 2011
    DOIhttps://doi.org/10.11213/tonyobyo1958.14.287
    JOURNAL FREE ACCESS
    Download PDF (3024K)
  • [title in Japanese]
    1971 Volume 14 Issue 5 Pages 302-303
    Published: September 30, 1971
    Released on J-STAGE: August 10, 2011
    DOIhttps://doi.org/10.11213/tonyobyo1958.14.302
    JOURNAL FREE ACCESS
    Download PDF (370K)
  • [title in Japanese]
    1971 Volume 14 Issue 5 Pages 304-312
    Published: September 30, 1971
    Released on J-STAGE: August 10, 2011
    DOIhttps://doi.org/10.11213/tonyobyo1958.14.304
    JOURNAL FREE ACCESS
    Download PDF (1729K)
  • [title in Japanese]
    1971 Volume 14 Issue 5 Pages 313-320
    Published: September 30, 1971
    Released on J-STAGE: August 10, 2011
    DOIhttps://doi.org/10.11213/tonyobyo1958.14.313
    JOURNAL FREE ACCESS
    Download PDF (1787K)
  • [title in Japanese]
    1971 Volume 14 Issue 5 Pages 321-323
    Published: September 30, 1971
    Released on J-STAGE: August 10, 2011
    DOIhttps://doi.org/10.11213/tonyobyo1958.14.321
    JOURNAL FREE ACCESS
    Download PDF (693K)
  • [title in Japanese]
    1971 Volume 14 Issue 5 Pages 323-328
    Published: September 30, 1971
    Released on J-STAGE: August 10, 2011
    DOIhttps://doi.org/10.11213/tonyobyo1958.14.323
    JOURNAL FREE ACCESS
    Download PDF (1277K)
  • [title in Japanese]
    1971 Volume 14 Issue 5 Pages 329-342
    Published: September 30, 1971
    Released on J-STAGE: August 10, 2011
    DOIhttps://doi.org/10.11213/tonyobyo1958.14.329
    JOURNAL FREE ACCESS
    Download PDF (3026K)
    • |<
    • <
    • 1
    • >
    • >|
feedback
 Top