The influenza vaccine now used is of an aqueous type : it causes many side-effects mainly consisting of influenza-like symptoms on inoculation, and its immune value is kept merely for a short period of time : thus, there are some problems to use the said vaccine . While, the mineral-oil adjuvant vaccine which has been developed from the standpoint of the immune effect is excellent in its effectiveness, but it has also some problems on using practically, as it causes induration including the carcinogenes due to mineral oil. The author examined the results of a metabolizable adjuvant vaccine in a field experiment, as it can be developed according to the success of making sesame oil adjuvant . Treatment of the virus with ether, which is presumed to be developed in future, was also examined. The vaccines examined and compared were five ; that is, an aqueous vaccine (Plain-V), its ether-treated one (ET-Plain-V), two sesame oil vaccines (Meta-V, ET-Meta-V .), and a mineral-oil vaccine (Mine-V). 1. The influenza-like symptoms due to side-effects appeared less with Plain-V, ET-Plain-V and Mine-V. 2. Redness was seen similarly with the five vaccines, but induration was hardly observed with Plain-V, ET-Plain-V, Meta-V, and ET-Meta-V. 3. The HI value was observed : 3 months after inoculation, Meta-V and ET-Meta-V showed the antibody value the same to that of Plain-V one month after inoculation ; thus, the former two exhibited a prolonged effect, which was however inferior to that of Mine-V. 4. The ether-treated vaccine was not so effective as expected in this experiment . Judging from the above results, the sesame-oil adjuvant vaccine can be employed instead of the vaccine now used.
The paper deals with the comparative analysis of vital records on cardiovascular mortality among Japanese and both white and non-white population of the United States for the years of 1950, 1955 and 1960. The comparative analysis is carried out by calculating the age-sex-ad justed death rates for four selected cardiovascular diseases. Very high death rates from arteriosclerotic and degenerative heart disease with low rates from vascular lesions of the central nervous system are noted among the American populationn while the situation is reverse among the Japanese. Other notable results are presented. Considerable factors responsible to the results of the analysis are discussed. Results of the study is presented also in the recent issue of the Bulletin of the Heart Institute, Japan.
During a experimental period of 35 days five subjects had a stretch training on one leg by way of foot stretch ergometer every day. Time couse of pulse transmisson was studied by way of recording of pulse waves, especially on inclination and crest time. Blood pressure of poplitead and cubital arteries were recorded at each light days on the course of the training. The results obtained were as follows : 1. Pulse transmission time was slightly retarded on the trained foot. 2. Shortening of the inclination time and crest time was both noticeable, and the significance level for the crest time was less than 5%. 3. The poplitead blood pressure was slightly lower at the trained leg than that at other leg (P>0.05). 4. Systolic blood pressure measured at cubital artery was slightly increased, whereas diastolic pressure had a tendency of slight decrease. It was suggested that the pulse pressure increased slightly after the training period (P>0.05).