Growth inhibitory action against 24 kinds of bacteria, including
Streptococcus hemolyticus, Diplococcus pneumoniae Type I, and
Brucella melitensis, were tested with 13 kinds of compounds reported in Parts I to V of this series which showed strong growth inhibition against
Staphylococcus aureus 209 P,
Bacillus coli communior, and
Bacillus subtilis. None of them showed a very strong growth inhibition but 6-chloro-4-heptylresorcinol, 2-chloro-3-methyl-4-thiocyano-6-isopropylphenol,
p-nitrothymol, and 2, 4-dihydroxy-3-chloro-5-hexylbenzaldehyde thiosemicarbazone were able to completely inhibit the growth of
Streptococcus hemolyticus at 160, 000 dilution, 6-chloro-4-cyclohexylresorcinol, 2-chloro-4-acetylthymol,
p-nitrosophenol, 2, 4-dihydroxy-3-chloro-5-amylbenzaldehyde thiosemicarbazone, propyl olivetolcarboxylate, and sphaerophorin in 80, 000 dilution. 6-Chloro-4-heptylresorcinol, 2-chloro-3-methyl-4-thiocyano-6-isopropylphenol, and 2, 4-dihydroxy-3-chloro-5-hexylbenzaldehyde thiosemicarbazone completely inhibited the growth of
Diplococcus pneumoniae Type I in 160, 000 dilution, and 2-chloro-4-acetylthymol,
p-nitrothymol, propyl olivetolcarboxylate,
p-quinonedichloroimide, and sphaerophorin in 80, 000 dilution. 6-Chloro-4-heptylresorcinol,
p-nitrosophenol, 2, 4-dihydroxy-3-chloro-5-hexylbenzaldehyde thiosemicarbazone, sphaerophorin, and divaricatic acid complety inhibited the growth of
Bacillus anthracis in 80, 000 dilution. It should be noted that, as shown in the accompanying Table, sphaerophorin was the only one among the 13 compounds tested which was able to uniformly inhibit the growth of the bacteria tested, except six, although in 80, 000 dilution.
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