In order to explain the correlations of somei nteresting experimental results from the preceeding reports 2, 3, and 4 and some supplements were made and the phosgenation reaction mechanism has been investigated on these viewpoints. i. NaO-B1-ONa gives HO-B1-O·COCl, Cl·CO·O-B1-O·COCl and HO-Bn-O-COCl type origomers by the surface reaction with phosgene under dissolution in-to methylene chloride layer. ii. elevation the temperature from 0°c to 25°c during blow-in of phosgene a direct formation of origomer from NaO-B1-O·COCl and decreases a formation of origomer through Cl·CO·O-B1-O·COCl. iii. Increase of the amount of sodium hydroxide during blow-in of phosgene cause an increase of formation of Cl-CO-O·B1-O·COCl and the ratio of (-O·COCl/OH) terminal groups of origomer due to the increase of the ratio of NaO-B1-O-COCl to HO-B1-O·COCl
Ambrette musk has a chemical structure of 2, 4-dinitro-6-t-butyl-1-anisole and elegant musk-like aroma. The usual method of its synthesis is as follows; cresol is used as a raw material, its phenolic hydroxyl group is converted into a methoxy group, then t-butyl group is introduced, and finally two nitro groups are introduced The author tried to introduce t-butyl group in m-cresol at first, and then convert the phenolic hydroxyl group into methoxy group and finally to introduce two nitro groups, and then succeeded to produce ambrette musk with good yield. A new synthetic procedure having many advantages for present process was thus established.
Several dyes having chloromethyl group were synthesized by coupling of various coupling components with diazo component derived from o- and m-aminobenzyl chloride. The water-soluble dyes containing diazo group derived from m-aminobenzyl chloride are fast dye reactive with cellulose in the presence of sodium carbonate at high temperature, but dyes with the diazo component derived from o-aminobenzyl chloride showed no reactivity on cellulose.
The mechanism of the formation of melamine from dicyandiamide-acetone addition product with alkaline was studied. A new compound, cyanobiguanide was confirmed as an intermediate of this process. This compound was converted to melamine easily and quantitatively with alkaline at room temperature. Some properties of this eompound were also investigated.