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Volume 31, Issue 3
Displaying 1-16 of 16 articles from this issue
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Kazutoyo KOBAYASHI, Kazuo SHIMODA, Yukihiro SOMEKAWA, Fumiaki SHIDOH, ...1985 Volume 31 Issue 3 Pages 455-460
Published: May 20, 1985
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSTwenty two adults with acute epiglottitis were discussed. Four required tracheostomy because of delayed diagnosis. There were no deaths. Epiglottitis occures more often in adults than is generally recongnized. The early symptoms of epiglottitis in adults are sore throat and dysphagia. Seventeen occurrences were in malas, hence, establishing an 3.4:1 male: female incidence ratio. The mean age at the time of affliction was 43.4 years. Throat and blood cultures were obtained from fifteen cases. Cultures from only three patients were positive for H. influenzae and streptococcus. The mean white blood cell count was 14, 800 with a left shift of the granulocytic series. The mean blood sedimentation rate was 58.7mm in 1 hour. The X-ray appearance of acute epiglottitis was so characteristic and striking that it cannot be confused with any others. The epiglottis and aryepiglottic folds were swollen and appeared to fill the hypopharynx. The swelling stopped abruptly at the level of the glottis, the subglottic larynx and trachea being clear. The primary treatment of adult with epiglottitis was intravenous steroids, antibiotics, and humidified oxygen. Tracheostomy was indicated if the disease progressed during the first six hours of treatment.View full abstractDownload PDF (4866K) -
Yoshio UMEDA, Mototoshi KIMURA1985 Volume 31 Issue 3 Pages 461-465
Published: May 20, 1985
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSOur experience in the treatment of twelve cases with ear bleeding and hemotympanum caused by head trauma has indicated strongly that the following early procedure is effective in such cases: 1. Cleanse the external auditory canal quickly after the injury and ascertain the site of bleeding. If the bleeding is due to injury of the external auditory canal, try to stop bleeding. If this fails, insert a piece of gauze and retry hemostasis the next day. 2. When the bleeding stops, insert gauze with antibiotic ointment in order to prevent the external auditory canal from local infection, and remove it the following day. 3. If the hemotympanum still exists even a week after the injury, incise the eardrum. 4. Administer bilateral inner ear anaesthesia about ten days after the injury, even if positional nystagmus does not appear. 5. Hearing and caloric examinations should invariably be done in cases with ear bleeding.View full abstractDownload PDF (593K) -
A 9-years reviewKenji MORIMOTO, Kazuko ENOMOTO, Kazutoyo KOBAYASHI, Katsufumi HOKI, Ak ...1985 Volume 31 Issue 3 Pages 466-470
Published: May 20, 1985
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSThirty patients with cystic lesion of paranasal sinus with orbital complications were treated at our clinic from April 1975 to March 1984. In this series, all cases are reviewed, covering a 9 year period, with a male: female sex ratio of 11:19. The 30 cases were classified into 4 groups, according to the location of the cystic lesion, 1) frontal type, 1 case, 2) front-ethmoidal type, 15 cases, 3) ethmoidal type, 13 cases, 4) ethmoidsphenoidal type, 1 cases. Of all cases, 22 had past history of chronic sinusitis, and 13 had previously undergone nasal or paranasal surgery. The average age of the onset of symptom in these cases was 43.7 years. On the other hand, in the cases without prior surgery the average age was 55.1 years. In all cases operation were performed and orbital bone destruction was found in 28 case. Etiology and pathogenesis of cystic lesion of paranasal sinus with orbital complications are discussed.View full abstractDownload PDF (646K) -
One-Day CAP regimenTohru FURUSAKA, Akinori KIDA, Nobuo KUKIMOTO, Yutaka YOKODE, Yukari HO ...1985 Volume 31 Issue 3 Pages 471-477
Published: May 20, 1985
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSA combined chemotherapy with Cyclophosphamide (CPM), Adriamycin (ADM) and Cis-Platinumdiamminedichloride (CPDD) was performed on ten patients with advanced, recurrent or metastatic head and neck malignant tumors, and the therapeutic of were investigated. CPM at a dose of 300mg/m2, ADM at a dose of 30mg/m2 and CPDD at a dose of 40mg/m2 were administrated intravenously or intraarterially in one day after hydration of the patient. Of ten cases, one case had a complete response and two cases had a partial response, thus the response rate was 30%. In view of histological findings, therapeutic effects were observed in anaplastic carcinoma and adenocarcinoma, while no effects was observed on squamous cell carcinoma which had already been treated by radiotherapy and surgery. Two cases which had a low performance status were treated effectively with One-Day CAP regimen. The therapy was less effective in cases with a high performance status. Toxic effects associated with combined chemotherapy were nausea, vomiting, leucopenia, anemia and fever. However, the symptomes were temporary and they were not severe. These results lead to the following conclusion: One-day CAP therapy is useful for anaplastic carcinoma and adenocarcinoma, and also it is useful as a neo-adjuvant chemotherapy prior to surgery and/or radiotherapy.View full abstractDownload PDF (3844K) -
Nobukiyo SATOH, Yoshihiko TERAYAMA1985 Volume 31 Issue 3 Pages 478-480
Published: May 20, 1985
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSA case of sarcoidosis of the larynx and the lip was reported. The laryngeal sarcoidosis is very rare and this is the second report in the Japanese literature. A 49-year-old female complained of hoarseness and lip swelling. Indirect laryngoscopy showed swelling of the epiglottis and arytenoid, but the true vocal cords were intact. Diagnosis was extablished by three biopsies at different times and two Ga scintigrams. Biopsy of the tonsil and CT scanning supported the diagnosis.View full abstractDownload PDF (3089K) -
Hiromi ARA, Eiji AZUMA, Kazutoyo KOBAYASHI, Kazuko ENOMOTO, Akikatsu K ...1985 Volume 31 Issue 3 Pages 481-485
Published: May 20, 1985
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSA Clinical investigation was performed on 28 cases of vocal cord nodule (V. C. N.), 231 cases of vocal cord polyp (V. C. P.) and 65 cases of polypoid vocal cord (Polypoid V. C.). Of all the cases, 162 were male and the same number were female. All of the male cases with V. C. N. were under 14 years old, while 83% of the female cases were over 20 years old. Of the patients with V. C. P., 81% were in the thirties, forties, and fifties. Of the patients with polypoid V. C., 66% were in the forties and fifties. The incidence of bilateral ceses were 93% in V. C. N., 89% in polypoid V. C. and 29% in V. C. P. The average duration of the symptoms was 18 monthes in V. C. N., 24 months in V. C. P. and 123 months in polypoid V. C. The incidence of the smoking in the adult patients was high in all three diseases, especially polypoid V. C. The incidence of vocal abuse was relatively high in V. C. N.View full abstractDownload PDF (579K) -
Shinya SOHMA, Kohji ASAKURA, Yukihiro SOMEKAWA, Akikatsu KATAURA1985 Volume 31 Issue 3 Pages 486-492
Published: May 20, 1985
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSFrom 1978 to 1981, six cases of laryngeal tuberculosis were experienced in Department of Oto-Rhino Laryngology, Sappro Medical College. The age of the patients ranged from 22 to 69 years old with a mean of 48.5 years. Their chief complaints were hoarseness except case 3 whose complaint was dyspnea. Five cases were pointed out the abnormal shadows in their chest X-rays. Case 1 was initially treated with the clinical diagnosis of ulcerative stomatitis without definite cause untill culture of his sputum was reported positive for tubercle bacilli. Case 5 was thought to be the rare case of primary laryngeal tuberculosis. Five cases showed granulomatous lesion in their larynx and two cases were confused with laryngeal carcinoma. Case 3 and case 4 were suffered from subglottic granulomatous lesion and case 4 also showed the tenderness and swelling of the thyroid region. In case 3 dyspnea appeared due to subglottic stenosis with scar in spite of the antituberculous chemotherapy. We have discussed in this paper six cases of various clinical symptoms of laryngeal tuberculosis.View full abstractDownload PDF (9486K) -
A cervical-transpharyngeal approach with midline mandibulotomyAkiteru YUMISAKI, Goro MOGI, Tatsuya FUJIYOSHI1985 Volume 31 Issue 3 Pages 493-496
Published: May 20, 1985
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSThe parapharyngeal space, deep within the neck at the level between the base of skull and the apex of the greater cornu of the hyoid bone, is an anatomically important region. This space is surrounded by the mandible, parotid gland, pterygoid muscles laterally, and pharyngeal muscles medially. The internal carotid artery, internal jugular vein and 9th, 10th, 11th and 12th cranial nerves pass through this space. It is well known that benign and malignant tumors occasionally rise in this space and that most of them are not detected until they extrude medially or laterally. We experienced in a 30 year-old woman, a large parapharyngeal space pleomorphic adenoma 80g in mass originating from the deep lobe of the parotid gland. The tumor was removed by a cervical-transpharyngeal approach with midline mandibulotomy, in order to avoid the damage of vessels and nerves.View full abstractDownload PDF (6304K) -
Hidekazu YAMAMOTO, Kuniko MATSUYAMA, Hiroshi FUJITA, Nobuko NAKAGAWA, ...1985 Volume 31 Issue 3 Pages 497-502
Published: May 20, 1985
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESS1) Cefmetazole (CMZ) 2g was administered intravenously to preoperative patients of tonsils admitted for tonsillectomy. Under local anesthesia, the tonsil was removed, and assayed for CMZ concentration. As a results, the CMZ concentration in tonsillar tissue attained a peak value a 0.5 hours after I. V. administration. the mean concentration was 11.8 μg/g, and the transfer rate was about 20% from serum to tonsillar tissue. 2) CMZ was administered to 20 patients with severe infections in the ear, nose, and throat and excellent response was observed in 16 cases, good responses in 3 and a poor response in 1.3) It is suggested that CMZ should be the antibiotic of choice for deep neck infections.View full abstractDownload PDF (681K) -
Hitoshi OGINO, Toru MATSUNAGA1985 Volume 31 Issue 3 Pages 503-508
Published: May 20, 1985
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSCoenzyme Q10 is said to increase the efficiency of oxygen utilization and ATP production in ischemic tissue. The present study was undertaken to determine the blood levels and clinical effects of Coenzyme Q10 in 83 patients with vertigo. The mean blood level of Coenzyme Q10 in 83 patients with vertigo was 0.61±0.27 μg/ml, which was lower than the normal value of 0.81±0.34 μg/ml (p<0.01). Blood levels of Coenzyme Q10 were significantly lower in patients with sudden deafness, central dizziness and vertigo than in those with MÉNIÈRE's disease. The time course of vertigo was followed in the MÉNIÈRES's disease patients in whom blood levels of Coenzyme Q10 could be determined at various times. As a result, it was found that there was a correlation between blood levels of Coenzyme Q10 and vertigo. Briefly, the mean blood level of Coenzyme Q10 was 0.72±0.22 μg/ml during remission, while it was 0.43±0.19 μg/ml when the patients were conscious of vertigo. After 2 weeks of treatment the clinical effects of Coenzyme Q10 on vertigo were determined in a group of 14 patients on Coenzyme Q10 (Neuquinon) alone, 30-90mg/day, and in a group of 23 patients on combination therapy with Coenzyme Q10 (Neuquinon), 60-90mg/day, and an cerebral metabolic activator. The drug effect evaluations were in principle made on the basis of changes in subjective and objective symptoms at the end of treatment period. The rate of effectiveness was 90% for patients on combination therapy and 35.7% for those on single therapy with Coenzyme Q10. This result suggests that the transport of Coenzyme Q10 to tissue is enhanced when it is combined with an excitometabolic cardiovascular drug and that they pharmacologically produce a synergistic effect with each other.View full abstractDownload PDF (777K) -
Kenichiro MIYAMURA, Masao EURA, Kenjiro KITAO, Takeru ISHIKAWA1985 Volume 31 Issue 3 Pages 509-514
Published: May 20, 1985
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSThe mesenchymal chondrosarcoma is a very rare neoplasm. A case of extraskeletal mesenchymal chondrosarcoma occurring in the left temporal fossa was reported. The patient was a 15-years-old Japanese female with a painless swelling of the left temporal region. Total removal of the tumor was then undertaken. From the findings of surgical operation, the tumor existed in the temporal muscle well separated from other surrounding tissue. The tumor was histologically diagnosed as mesenchymal chondrosarcoma originated from the temporal muscle, which was the first case in Japan. Chemotherapy with Adriamycin and Vincristin were given after the operation. About 17 months after the first operation, local recurrence was seen in the left preauricural region. Then, total removal of the tumor and postoperative chemotherapy with Aclacinon was performed. No recurrence was seen for 21 months after the last operation. The mesenchymal chondrosarcoma is characterized histologically by composition of sheets of highly undifferentiated mesenchymal cells and islands of relatively well-diffrentiated cartilage. This histological feture is sometimes difficult to distinguish from hemangiopericytoma and reticulm cell sarcoma. Radical surgery appears to be the best treatment of choice.View full abstractDownload PDF (6201K) -
Kimio SHIRAISHI, Toyoji SODA, Toshihiko KATO, Shun-ichi MATSUDA, Yo-ic ...1985 Volume 31 Issue 3 Pages 515-524
Published: May 20, 1985
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSWe discussed fundamental problems and clinical application on the auditory brainstem responses to bone-conducted signals. 1. Measuring the frequency responses of three bone vibrators to 0.1V (rms) electric input, the one which had maximum output level in high frequency was seemed to be the most favorable to elicit bone-conducted ABRs. 2. The difference between the input power spectrum of electric sinusoidal one wave (0.5 KHz, 1 KHz, 2 KHz, and 4 KHz) and the output spectrum obtained from the artificial mastoid stimulated by the bone vibrator were compared, and then the results of the comparison were showed us the facts about frequency specificity of bone-conducted ABRs. 3. We have found clinical method to determine better hearing ear site by means of bilateral recording of bone-conducted ABRs, in a case those who could not be masked because of bilateral severe conductive hearing loss.View full abstractDownload PDF (1305K) -
Shunkichi BABA, Haruji KINOSHITA, Yoshito MORI, Takuji TOMURA, Mieko Y ...1985 Volume 31 Issue 3 Pages 525-568
Published: May 20, 1985
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSIn order to evaluate the clinical of and safety of Cefmenoxime (CMX) otic solution on purulent otitis media, a double blind clinical test was carried out by means of topical administration of CMX otic solution and placebo respectively to the patients with chronic purulent otitis media and its acute exacerbatins. Cefalexin was orally administered as basic treatment. Both 90 patients treated with CMX otic solution and 90 patients with placebo were subjected to the clinical evaluation. The effectiveness rate including “remarkably effective” and “effective” observed in CMX group by the judgement of chief physicians was 75.6%, while placebo group showed 41.1% of effectiveness rate (p≤0.001). By the judgement of the committee member, however, 75.6% effectiveness rate was obtained in CMX group and 37.8% in placebo group respectively (p≤0.01), and thus, the clinical efficacy of CMX otic solution was confirmed statistically. With respect to the bacteriological efficacy judged by the committee member, CMX otic solution exerted an antibacterial effect on S. aureus and P. aeruginosa and the total bacteria eradication rate was 71.4% with CMX and 38.0% with placebo, the significant difference being observed between the two groups (p≤0.001). As to the safety of CMX otic solution, side effects were observed in 3 cases among 100 patients treated with CMX otic solution (3.0%) and also in 3 cases among 97 placebo treated patients (3.1%). All the side effects observed were transient and not severe at all. CMX otic solution was confirmed, therefore, to be a highly tolerable and safe preparation. It is concluded that, based on the above clinical test results, 1% CMX otic solution which possessed an excellent antibacterial activity, is quite an efficacious and safe topical preparation for the treatment of purulent otitis media.View full abstractDownload PDF (3620K) -
Hitome KOBAYASHI, Kenshi YAMAMOTO, Hiroyuki ZUSHO1985 Volume 31 Issue 3 Pages 569-576
Published: May 20, 1985
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSLysozyme chloride (Neuzym), an antiphlogistic enzyme preparation and Saibokuto, a Chinese medicine were administered to cases of abnormal sensation of the pharynx showing no marked organic diseases, and a comparative study was made of their efficacy. 1. The subjects used were 48 cases administered Saibokuto and 47 cases administered Neuzym for a total of 95 cases. There was no significant difference in the age and background factors between these subjects. 2. The improvement rating for subjective symptoms stood at 77.8% for Saibokuto and 57.1% for Neuzym. 3. Side-effects were observed in one case each of either drug, but disappeared with discontinuation of the medication. 4. The usefulness was 77.8% for Saibokuto and 51.7 % for Neu ym, there being no significant difference.View full abstractDownload PDF (802K) -
Shunkichi BABA, Haruji KINOSHITA, Yoshito MORI, Hirokazu SHIBUI, Buemo ...1985 Volume 31 Issue 3 Pages 577-593
Published: May 20, 1985
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSWe conducted a clinical study on Aspoxicillin (ASPC, TA-058), a newly synthesized penicillin, in paranasal sinusitis and the following results were obtained. 1) The clinical response was obtained in 59.2% (29/49) as judged by doctors in charge. 2) Based on the criteria of the evaluation committee, the clinical response was obtained in 60.5% (26/43). 3) Bacteriologically, the percentage eradication of causal organisms was 79.5% (35/44). 4) Adverse reaction was observed in 1 of the 63 cases (1.6%). From the above findings, it is presumed that ASPC is an useful antibiotic for the treatment for paranasal sinusitis.View full abstractDownload PDF (1788K) -
[in Japanese]1985 Volume 31 Issue 3 Pages 594-595
Published: May 20, 1985
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSDownload PDF (274K)
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