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Volume 51, Issue 6
Displaying 1-11 of 11 articles from this issue
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Buichiro TAKASE2005 Volume 51 Issue 6 Pages 391-402
Published: November 20, 2005
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSThe articulatory or swallowing function was investigated in 140 patients who underwent a surgical resection for carcinoma of either the oral cavity or the oropharynx at Kurume University Hospital. There were 112 (80 males and 32 females) oral cavity patients and 28 (25 males and 3 females) oropharyngeal cancer patients. In the analyses, the correlation between the articulatory or swallowing function and the primary site, tumor stage and the degree of surgical resection were examined. In patients with oral cancer, both functions were well preserved in the group undergoing a resection comprising less than half of the anterior tongue. However, in the group with a wide range resection, the articulatory function was invariably impaired. In patients with oropharyngeal cancer both functions were impaired when the degree of the anterior and superior wall resection increased. In the patients with a poor postoperative articulatory function, a severe postoperative swallowing dysfunction persisted. These results highly indicate that the articulatory and swallowing function are closely correlated with each other in patients undergoing a resection of either oral or oropharyngeal cancers.View full abstractDownload PDF (21275K) -
Kazuhide TOMITA2005 Volume 51 Issue 6 Pages 403-410
Published: November 20, 2005
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSWe investigated the expression of p53 protein in 81 patients (X males and Y females) with squamous cell carcinoma of the hypopharynx. In our examination, histopathologic evidence in the metastatic lymph nodes, such as the spread of extracapsular cancer cells, necrosis, the disappearance of lymphoid follicles and fibrotic changes were all checked and their relationship to the expression of the p53 oncoprotein was also analyzed. A positive p53 protein expression was detected in 43 of the 81 patients (54%). There were no statistically significant correlations between the survival rates, local or neck control rates and the p53 expression. On the contrary, distant metastasis was predominantly detected in cases with a p53 expression (p<0.05). The present study suggests that examining the expression of p53 protein therefore appears to be a valuable modality for predicting the clinical course of hypopharyngeal squamous cell cardinoma.View full abstractDownload PDF (15031K) -
Takashi KIMITSUKI, Shizuo KOMUNE2005 Volume 51 Issue 6 Pages 411-416
Published: November 20, 2005
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSThe Eustachian tube (ET) function was studied by sonotubometry prior to hyperbaric oxygen therapy (HBO) in seventy-one ears. The correlation between the results of sonotubometry and middle ear barotraumas were then studied. Of the 46 ears without any symptoms, 19 ears (41%) demonstrated an ET dysfunction. Of the 17 ears with slight symptoms, 8 ears (47%) demonstrated an ET dysfunction. Of the 8 ears with severe barotraumas, 6 ears (75%) demonstrated an ET dysfunction. There were no significant differences among these three groups. Of the 39 ears showing a normal tympanic membrane after HBO therapy, 14 ears (36%) demonstrated an ET dysfunction. In contrast, of the 28 ears showing a pathologic appearance of the tympanic membrane, 18 ears (65%) demonstrated an ET dysfunction, thus indicating a significant difference between these two groups.View full abstractDownload PDF (10212K) -
Takashi NAKAGAWA, Tomoko MAKISHIMA, Yasuhiro KAKAZU, Shumei SHIBATA, S ...2005 Volume 51 Issue 6 Pages 417-422
Published: November 20, 2005
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSWe herein report of patient with a point mutation at the mitochondrial DNA position 3243, in whom a functional hearing loss persisted from childhood. A 20-year-old female visited us with the chief complaints of a hearing impairment and tinnitus. Pure tone audiometry showed a sensorineural hearing loss and her hearing level was 107dB for the right ear and 77dB for the left ear. Afterher marriage, she experienced insomnia and appetite loss and she was diagnosed to be in a depressive state. Treatment for depression improved her tinnitus and hearing impairment. Since her family history indicated hereditary features of deafness, a genetic analysis was performed. Her mitochondrial DNA had an A to G point mutation at nucleotide 3243. An auditory brainstem response was performed to assess her objective hearing level because of inconsistent fluctuations in both her hearing level and subjective hearing. The test showed that her objective hearing level was normal, and she was therefore diagnosed to have a functional hearing loss. We speculate that psychiatric symptoms related to the mitochondrial DNA 3243 point mutation might thus have resulted in the expression of a functional disorder.View full abstractDownload PDF (12400K) -
Kiyoshi HAMANO, Toyohiko MINAMI, Nobuko NAKAGAWA, Naoki TADA, Chiyonor ...2005 Volume 51 Issue 6 Pages 423-427
Published: November 20, 2005
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSWe herein report a case of tuberculosis of the parotid gland. The patient was a 63-year-old man who had an enlarged swelling of the parotid gland. A physical examination showed a mass in the parotid gland but no swelling of the neck lymph node or facial palsy. The cytological findings indicated a suspected Warthins tumor. We therefore performed an operation without performing a pathological examination during the operation under general anesthesia because of the diagnosis of a Warthins tumor. The postoperative pathological findings showed tuberculosis for all six tumors. Tuberculosis of the parotid gland is a variegated disease which only rarely shows facial palsy. Six tumors were found in the intraparotid gland in this case. In has been reported that tuberculosis of the parotid gland has recently increased, and we therefore recommend that a rapid pathological examination of such patients should thus be performed during the operation to make an accurate differential diagnosis.View full abstractDownload PDF (8610K) -
Hideaki KATORI, Mamoru TSUKUDA, Junichi ISHITOYA, Toshiro KAWANO, Masa ...2005 Volume 51 Issue 6 Pages 428-431
Published: November 20, 2005
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSThe clinical future and treatment outcomes were investigated in 20 patients with minor salivary gland tumors, consisting of 10 benign tumors and 10 malignant tumors. The hard palate was the area most frequently involved. In the benign tumors, 9 cases were pleomorphic adenomas, while in the malignant tumors, there were 3 adenocarcinomas, 3 mucoepidermoid cardinomas, 3 adenoidcystic carcinomas and 1 acinic cell carcinoma. In the benign tumors, all cases underwent surgery and no recurrence was obsderved. In the malignant tumors, 5 cases underwent surgery at first, and 3 cases recurred and thereafter received chemoradiotherapy (CAP: cyclophosphamide (CPA), doxorubicin (DXR), and sisplatin (CDDP)). Two cases underwent chemoradiotherapy at first followed by an operation and there was no recurrence. In addition, 3 cases were inoperable and they only received chemoradiotherapy. Preoperative chemoradiotherapy may therefore reduce the rate of recurrence in minor salivary gland carcinoma.View full abstractDownload PDF (7760K) -
Akihito WATANABE, Masanobu TANIGUTI, Hitoshi TSUJIE2005 Volume 51 Issue 6 Pages 432-436
Published: November 20, 2005
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSWe reviewed 415 patients with sinusitis evaluated by X-ray images who ranged from 3 to 9 years of age at first visit from 1995 to 2003 at our hospital. All patients were treated with clarithromycin 5-6mg/kg in two daily doses. The rate of clinical improvement was about 70% at 3 months and about 90% at 6 months after the start of administration. The rated of recurrence was about 30%. However, the subsequesnt therapy was as effective as the intial therapy. The rates of improvement and recurrence, as well as the period from improvement to recurrence showed no significant difference among the groups. These results therefore indicate that low-dose, long-term clarithromycin therapy appears to be useful not only as an initial therapy but also as an effective treatment for recurrence.View full abstractDownload PDF (10477K) -
Kousuke AKIYAMA, Masayuki KARAKI, Ai MATSUBARA, Nozomu MORI2005 Volume 51 Issue 6 Pages 437-441
Published: November 20, 2005
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSWe report a case of a maxillary cyst with a foreign body in the maxillary sinus. A 77-year-old woman presented with a left nasal obstruction and mucopurulent discharge. CT showed a left maxillary cyst containing a foreign body, and endoscopic sinus surgery to remove the foreign body was necessary. The removed foreign body turned out to be a fragment of a tooth. After surgery, the patient's symptoms disappeared.View full abstractDownload PDF (9307K) -
Kenichi NARIYAMA, Toshiro UMEZAKI, Aya ITO, Yasuhiro KAKAZU, Kyoko CHU ...2005 Volume 51 Issue 6 Pages 442-448
Published: November 20, 2005
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSTeratomas are germ cell tumors which derive from an embryonic origin consisting of three germinal layers including an endoderm, a mesoderm, and an ectoderm. The most common sites of origin appear to be the sacrococcygeal area and genital organs, such as the ovaries and testes. Teratomas of the head and neck especially the pterygopalatine fossa are very rare. We herein report a case of a teratoma found at the left pterygopalatine fossa. The patient was a 1-year and 5-monthold male. He had been suffering from rhinotthea, repeated left titis media and left cervical swelling. Computed tomography (CT) and magnetic resonance imaging (MRI) revealed a 6cm×4cm tumor in the left pterygopalatine fossa. To remove the tumor we used the infratemporal fossa approach (transorbitozygomatic approach) and the tumor was totally excised. A histopathological examination of the excised tumor showed three germinal layers and the tumor was thus diagnosed to be a teratoma. After the operation, lockjaw occurred. However, the symptoms of lockjaw have since increasingly improved. During the 2 years and 5 months since the operation has been performed, neither recurrence nor any swelling of the tumor site have been observed.View full abstractDownload PDF (11773K) -
Takahiro WAKASAKI, Yuichi SHINZATO, Shizuo KOMUNE2005 Volume 51 Issue 6 Pages 449-455
Published: November 20, 2005
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSWe experienced a case of acute epiglottitis who required a needle cannulation of the cricothyroid membrane due to the development of a deep cervical abscess. We diagnosed the acute epiglottitis using a larynx fiber. He had no symptoms except for a sore throat and a slight fever. However, he demonstrated an airway obstrection three hours after coming to the hospital. We performed needle cannulation of the cricothyroid membrane and he could thus thereafter successfully breathe a little. Next, he underwent a tracheotomy. We administered antibiotics to him intravenously, but a cervical abscess became obvious on the third day of hospitalization. The rejection pus from the incision outside the cervix area was aspirated and the patient was able to leave the hospital on the 39th day of hospitalization. Cases with acute epiglotittis associated with a cervical abscess have sometimes been reported to exist. The risk factors for developing acute epiglottitis have been reported to be smoking, diabetic mellitus, aging, a rapidly worsening condition, tachycardia, a WBS elevation and an extension of larynx imflammation. It is necessary to examine the airway management positively in cases who have these risk factors.View full abstractDownload PDF (12910K) -
Tamotsu MORIMITSU2005 Volume 51 Issue 6 Pages 456-462
Published: November 20, 2005
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSFrom the therapeutic results of Urografin®(U), which is an anionic contrast media for angiography, the focus of sudden deafness is presumed to be at the luminal surface of the vessel in the Stria vascularis. Electron microscopically, U-molecules as AgI granules were observed densely on the endolymphatic surface of the marginal cell. And the anionic sites with sialic acid were recognized at the luminal surface of the vessel, Those anionic sites were presumed to be voltage-sensitive Na+ channel. However, no anionic sites on the endolymphatic surface of the marginal cells were recognized. Electrophysiologically, positive potential in the strial cells was reported by Ohyama, and the existence of an ionic charge barrier is considered between the vessel and the stria composing cells in the Stria vascularis. This positive potential was maintained always in positive value even EP decreases in negative by anoxia and Furosemide injection. Ohyama reported also that the strial positive potential was decreased clearly by injection of Na+ into the stria, but not by injection of K+. From the above mentioned experimental grounds, it is concluded that U-molecule can not adhere at the luminal surface in normal condition, although it adheres at the passively cationized anionic sites at the luminal surface in sudden deafness inducing the therapeutic effect.View full abstractDownload PDF (13685K)
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