jibi to rinsho
Online ISSN : 2185-1034
Print ISSN : 0447-7227
ISSN-L : 0447-7227
Volume 39, Issue 1
Displaying 1-12 of 12 articles from this issue
  • Kensai SHIRABE, Shinichiro SHIRABE
    1993 Volume 39 Issue 1 Pages 1-6
    Published: January 20, 1993
    Released on J-STAGE: May 10, 2013
    JOURNAL FREE ACCESS
    An oroantral fistula usually occurs following extraction of a tooth. It causes odontogenic maxillary sinusitis and must be closed if it is large and chronic. This is a difficult operation and various methods have been described. Hitherto, we have successfully carried out Sasaki-Zange's method in which the mucous membrane of the inferior nasal meatus is used for the operation. In 4 recent cases it was not possible to use the above method. In these cases the fistula was closed by implanting the fascia temporalis or fascia lata into the fistula from the antral side. A representative case is as follows: In a 24 year-old man who had already undergone radical antral surgery and whose mucous membrane of the inferior nasal meatus was absent, closure was attained by utilizing the fascia lata. Following radical antral surgery, the fascia is implanted and fixed from the antral side of the fistula.
    Advantages of using fasciae include:
    1) easy to obtain
    2) excellent implantation
    3) no absorption
    In spite of its excellent features there do not appear to be any reports on its use for closure of the antral fistula. This method of implanting the fascia has merit and is indicated for all cases.
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  • Shizuo KOJA, Kiyoshi NAGATA, Satoshi KAMIYA, Akio TOKUYAMA
    1993 Volume 39 Issue 1 Pages 7-12
    Published: January 20, 1993
    Released on J-STAGE: May 10, 2013
    JOURNAL FREE ACCESS
    Fourteen cases of adenoid cystic carcinoma of the head and neck treated at the Department of Otorhinolaryngology, University of the Ryukyus Faculty of Medicine, were reviewed. The ages of the cases ranged from 26 to 72 years, with an average age of 45.8 years. Of the 14 cases, 7 were male and 7 were female. The average period from the initial symptoms to the first clinical visit was 2.4 years. The adenoid cystic carcinoma was located in the parotid in 4 cases, in the maxillary sinus in 3, and in the hard palate in 2. Eight cases were Stage III or Stage IV at the time their first visit to our department. Of the 14 cases, 12 had radical surgery and those with recurrences were administered radiation of more than 70 Gy. In some cases, chemo-radiotherapy was effective. Surgery in the first instance was recommended to improve treatment results. In cases with a distinct pathological pattern, wide excision and postoperative irradiation proved to be especially important. At the time of this report, eight cases survived without sign of tumor, 4 cases survived with tumor, and 2 cases had died from lung metastasis.
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  • Kohtaro YAMASHITA, Shuji SAWAKI, Akiko TANIUCHI, Chihiro NAKAGAWA, Koi ...
    1993 Volume 39 Issue 1 Pages 13-22
    Published: January 20, 1993
    Released on J-STAGE: May 10, 2013
    JOURNAL FREE ACCESS
    The combined effect of norfloxacin (NFLX) and carbocisteine (SCMC) on paranasal sinusitis was examined. Cases with acute paranasal sinusitis and acute exacerbation of chronic paranasal sinusitis were randomly divided into two groups. One group (38 cases) was administered NFLX alone 600mg/day p. o. for 14 days. The other group (36 cases) was treated with the combination of NFLX 600mg/day and SCMC 1500mg/day p. o. for 14 days. The following results were obtained.
    1. The overall clinical efficacy rate (cases of remarkably and moderately effective) was 66% in the NFLX alone group and 86% in the combined group. The effect of the combined group surpassed that of the NFLX alone group, especially in chronic cases.
    2. The overall effect on the nature of nasal discharge was observed in 73% of cases in the NFLX alone group and in 86% of the combined group. The overall effect on the volume of nasal discharge was observed in 84% of cases in the NFLX alone group and in 91% of the combined group. The combined therapy of NFLX and SCMC was found to be superior to that of NFLX alone for the improvement of the nature and volume of nasal discharge. These results indicate that combined therapy with NFLX and SCMC is a more useful therapeutic method for the treatment of paranasal sinusitis.
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  • Shigeki YOSHIKAWA, Yoshimitsu IKEDA, Osamu NISHIHIRA, Hitoshi FUKUI
    1993 Volume 39 Issue 1 Pages 23-27
    Published: January 20, 1993
    Released on J-STAGE: May 10, 2013
    JOURNAL FREE ACCESS
    A case of sudden onset hearing loss with vertigo following intracranial cavernous hemangioma in childhood is reported. An 8-year-old girl had a sudden attack of vertigo with left side hearing loss. On admission, symptoms were limited to the VIII th cranial nerve. CT and MRI examination showed a small mass in the left middle cerebellar peduncle and partial pons. The tumor was excised and pathological examination revealed a cavernous hemangioma. Previously, intracranial cavernous hemangioma was considered rare, but the increasing use of MRI has demonstrated numerous such cases. Typically, epileptic or other convulsive symptoms appear initially, but in our case, pathology was indicated by hearing loss with vertigo without other cranial nerve symptoms. This was a result of the localization of the tumor. We emphasized that in cases of sudden onset hearing loss, CNS lesions must be ruled out by thorough otoneurological examination for evidence of CNS symptoms. Because of their high resolutional capacity, CT and especially MRI studies are useful diagnostic tools in such cases.
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  • Noboru SAKAI, Kazuo ISHIKAWA, Masaki SATOH, Naoaki TERAKURA, Junichi M ...
    1993 Volume 39 Issue 1 Pages 28-31
    Published: January 20, 1993
    Released on J-STAGE: May 10, 2013
    JOURNAL FREE ACCESS
    A new method of simple in-office closure of the eardrum for troublesome small perforations after myringoplasty was introduced. This technique is an over-lay method using skin grafts from the cartilaginous ear canal with the removal of epithelia around the perforation following surface anesthesia of the eardrum. Six out of 7 ears treated with this method showed successful closure, a higher than average success rate. In one case, follow-up revealed that the closure was sustained for more than three years. Our new method has many advantages including superior cosmetic results, the requirement of extremely light anesthesia, and no necessity to pack the ear canal.
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  • Shinsuke ITO, Masao TAKETOMI, Motohiro HIRAKI, Mutsuko IDATE, Taketo K ...
    1993 Volume 39 Issue 1 Pages 32-34
    Published: January 20, 1993
    Released on J-STAGE: May 10, 2013
    JOURNAL FREE ACCESS
    The incidence and characteristics of postoperative tinnitus were analyzed on 83 cases of otitis media. Tinnitus occurred in a total of 14% of these cases. Sensorineural hearing loss was not associated with this symptom. The most prominent pitch of the patients' tinnitus varied. In half of the cases, tinnitus disappeared spontaneously within 3 months.
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  • Hideji TANIMOTO, Minoru OKUDA, Yuko ISHIDA, Terumichi FUJIKURA, Masaka ...
    1993 Volume 39 Issue 1 Pages 35-41
    Published: January 20, 1993
    Released on J-STAGE: May 10, 2013
    JOURNAL FREE ACCESS
    In a patient with perennial nasal allergy, we observed an aggravation of nasal symptoms following exposure to OS-oil, a substance used as an abrasive for stainless steel. In order to understand the etiology of OS-oil-induced aggravation of nasal symptoms, we sensitized the nasal mucosa of guinea pigs by challenge with OS-oil. We also challenged the nasal mucosa with methacholine after a further interval of 3 days. Secondary challenge with OS-oil showed minimal symptoms, but post OS-oil methachoiine challenge induced nasal hypersecretion and hypersensitivity. In the control group, not sensitized to OS-oil, methacholine challenge produced minimal symptoms. Thus, the aggravation of nasal allergy was found to be associated with nasal hypersecretion and hypersensitivity caused by OS-oil.
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  • Hidenobu TAIJI, Taketugu IKARI, Kouzou YAMADA, Manami NAGAMINE, Yae KA ...
    1993 Volume 39 Issue 1 Pages 42-48
    Published: January 20, 1993
    Released on J-STAGE: May 10, 2013
    JOURNAL FREE ACCESS
    We report four cases of Wegener's granulomatosis (WG). Two cases appeared initially with otitis media, and the other two presented with nasal symptoms. Our experience suggests guidelines for early diagnosis of WG. An otitis media resistant to antibiotic therapy, a nasal septal perforation, and a saddling of the nose are suspicious for WG. In serological testing, highly elevated ESR, strongly positive CRP, positive RA test, and increased serum fibrinogen are often found in WG. Anti-neutrophil cytoplasmic antibody (ANCA) is highly specific for WG (>95%), therefore it is useful for diagnosis of that condition. The main histopathologic features of WG are multinucleated giant cells, extensive necrosis, vasculitis, and infiltration of inflammatory cells (especially neutrophils).
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  • A Study in Vasomotor Rhinitis
    Minoru OKUDA, Tokuji UNNO, Yoshihisa SASAKI, Hiroshi TOMITA, Shunkichi ...
    1993 Volume 39 Issue 1 Pages 49-65
    Published: January 20, 1993
    Released on J-STAGE: May 10, 2013
    JOURNAL FREE ACCESS
    To evaluate its clinical efficacy and safety, Fluticasone Propionate Aqueous Nasal Spray (FP ANS) was administered to 79 patients with vasomotor rhinitis in the dose of 200mcg/day for at least 2 weeks in principle (One received for 21 weeks). The following results were obtained. 1. In the assessment of final overall improvement, cases judged as “markedly improved” or “moderately improved” accounted for 72.7%, and the cumulative rate including “slightly improved” cases was 92.7%. 2. An adverse reaction, mild palpitation, occurred in 1 case. No abnormality was observed in the clinical laboratory test values. Based on the above results, FP ANS was confirmed to be an effective and safe drug for the treatment of vasomotor rhinitis.
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  • Study of long term administration in perennial allergic rhinitis
    Minoru OKUDA, Tokuji UNNO, Yoshihisa SASAKI, Hiroshi TOMITA, Shunkichi ...
    1993 Volume 39 Issue 1 Pages 66-85
    Published: January 20, 1993
    Released on J-STAGE: May 10, 2013
    JOURNAL FREE ACCESS
    To evaluate its clinical efficacy and safety, Fluticasone Propionate (FP) Aqueous Nasal Spray was administered to 83 patients with perennial allergic rhinitis in the dose of either 200mcg/day (68 patients) or 400mcg/day (15 patients) for a long term of at least 4 weeks in principle (One received for 22 weeks). The following results were found. 1. In the assessment of final overall improvement, cases assessed as “markedly improved” or “moderately improved” accounted for a high rate of about 90%, and in almost all cases, at least a “slight improvement” was observed. In those cases in which maintenance of efficacy could be assessed, even 1 week after completion of treatment, efficacy was observed to be sustained in about 70%. 2. An adverse event occurred in 1 case and abnormalities in clinical laboratory test values were observed in 3 cases. However, they were all clinically insignificant and the incidence rate was not observed to increase in relation to the duration of the treatment period. Based on the above results, FP Aqueous Nasal Spray was confirmed as a drug with superior clinical efficacy, and judged as safe even when used for long term treatment.
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  • Comparative study vs. Fluticasone Propionate Aerosol
    Minoru OKUDA, Hiroshi TOMITA, Shunkichi BABA, Masaki ONISHI, Masakazu ...
    1993 Volume 39 Issue 1 Pages 86-106
    Published: January 20, 1993
    Released on J-STAGE: May 10, 2013
    JOURNAL FREE ACCESS
    In patients with perennial allergic rhinitis, clinical efficacy and safety of Fluticasone Propionate (FP) Aqueous Nasal Spray (ANS) and FP Aerosol were compared in a single blind study. 176 cases receiving 200mcg/day in two divided doses for 2 weeks were included in the analysis, and both drugs produced high improvement rates (total of the cases assessed as “markedly improved” and those as “moderately improved” : ANS 81% and Aerosol 70%). A low incidence of adverse reactions and abnormal clinical laboratory test values resulted in a high safety rating in the overall safety assessment (“high level of safety” : ANS 99% and Aerosol 100%). Clinical usefulness was assessed based on the efficacy and safety results, and both the drugs were judged as very useful (total of “very useful” and “useful” : ANS 81% and Aerosol 73%). Thus, both FP ANS and Aerosol were found to be useful drugs for perennial allergic rhinitis.
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  • Comparative study vs. Sodium cromoglycate Nasal Solution in perennial allergic rhinitis
    Minoru OKUDA, Tokuji UNNO, Yoshihisa SASAKI, Toru MATSUNAGA, Mitsuaki ...
    1993 Volume 39 Issue 1 Pages 107-127
    Published: January 20, 1993
    Released on J-STAGE: May 10, 2013
    JOURNAL FREE ACCESS
    In 201 patients with perennial allergic rhinitis, a single blind group comparative study was carried out in order to determine the clinical usefulness of Fluticasone Propionate (FP) Aqueous Nasal Spray, using Sodium Cromoglycate Nasal Solution as a control. Final overall improvement was significantly greater with FP than with Sodium Cromoglycate. Overall safety was not significantly different between the two groups. Usefulness was assessed based on final overall improvement and overall safety. Cases assessed as “very useful” numbered 49% (FP) and 12% (Sodium Cromoglycate),“very useful” plus “useful” accounted for 83% (FP) and 37% (Sodium Cromoglycate), and rates when including “slightly useful” were 97% (FP) and 76% (Sodium Cromoglycate), FP was significantly superior to Sodium Cromoglycate in clincal usefulness. Based on the above, FP Aqueous Nasal Spray was confirmed to have greater efficacy and equivalently high safety to Sodium Cromoglycate Nasal solution and thus was judged to be a highly useful drug for treating perennial allergic rhinitis.
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