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Volume 59, Issue 3
Displaying 1-9 of 9 articles from this issue
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Original Article
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Mihoko HARAGUCHI, Minoru GOTOH, Nozomu WAKAYAMA, Ayaho YOSHINO, Ryosuk ...2013 Volume 59 Issue 3 Pages 93-100
Published: May 20, 2013
Released on J-STAGE: June 01, 2014
JOURNAL FREE ACCESSA clinical study of 134 patients (65 males, 69 females) who started allergen immunotherapy in the Department of Otorhinolaryngology at Nippon Medical School Hospital between April 2010 and May 2012 was performed. We examined the age distribution, the initial and maintenance doses, the number of injections, the rate and the details of side effects, the number of patients who discontinued treatment, and the number of days that the patients took medication. There are 69 patients (51.5%) aged 30 to 49 years and 18 patients (13.4%) aged three to 14 years. There was a wider range of initial and maintenance doses for patients receiving Japanese cedar immunotherapy than for those with allergies to house dust. Five patients experienced a side effect during immunotherapy, but there were no fatalities. Twenty-two patients (16.4%) discontinued immunotherapy. Twenty-eight percent of the patients who received cedar immunotherapy did not need to take medication during the cedar season in 2012.View full abstractDownload PDF (1067K) -
Tatsuaki KURODA2013 Volume 59 Issue 3 Pages 101-107
Published: May 20, 2013
Released on J-STAGE: June 01, 2014
JOURNAL FREE ACCESSOver the past 20 years, 167 patients with tinnitus, probably caused by eighth cranial nerve neurovascular compression syndrome, visited my clinic. The short intermittent tinnitus lasting a few seconds occurred many times a day. I treated 163 patients with Tegretol. The male-to-female ratio of the patients was 57:110. Fifty seven percent, 95 out of 167 patients, developed tinnitus when they were old then 60. The majority of the patients, 164 out of 167 (98%) had unilateral tinnitus. There were no significant differences in the hearing between the tinnitus side and the opposite side. Tegretol proved very effective. The tinnitus completely disappeared in 69 cases and almost disappeared in 26 cases. The effect of tegretol was stronger in elderly patients. In the subgroup of patients with vertigo, tegretol was shown to be more effective than in the patients without vertigo. Many of the patients still had tinnitus lasting several days or months, which recurred every few years.View full abstractDownload PDF (2539K) -
Asako KISHIMOTO, Chiyonori INO, Naoki TADA, Toyohiko MINAMI, Motoko IN ...2013 Volume 59 Issue 3 Pages 108-114
Published: May 20, 2013
Released on J-STAGE: June 01, 2014
JOURNAL FREE ACCESSWe investigated the bacteria present in 62 cases of inflammation of the nasal vestibule. Staphylococcus aureus was the most frequently observed bacterium, and was present in 56 cases (90.3%). MSSA (methicillin-sensitive Staphylococci) were found in 40 cases (64.5%) and MRSA (methicillin-resistant Staphylococci) were found in 16 cases (25.8%). CNS (coagulase-negative Staphylococci) were present in three cases. Bacteria that cause sinusitis were rarely observed. We consider that angular cheilitis is often caused by the bacteria preset in saliva, while inflammation of the nasal vestibule is not caused by bacteria in nasal discharge, but by the normal flora following activation by some type of stimulus. The stimulation might be related to allergic rhinitis or the common cold, because it often occurs during the pollinosis season or in the winter, and rarely in the summer. The most effective antibiotic against MSSA was FMOX (100%), followed by MINO (97.5%). MRSA is classified into communityacquired MRSA (CA-MRSA), which is sensitive to MINO, and into hospital-acquired MRSA (HA-MRSA), which is resistant to most antibiotics. CA-MRSA accounted for 10 out of 16 cases of MRSA (62.5%). A high percentage (30.1%) of the patients older than 60 years showed MRSA colonization, and all six cases of HA-MRSA were included in this age group.View full abstractDownload PDF (587K) -
Kazunori MATSUDA, Kazunori SEKINE, Go SATO, Haruhiko SHIZUKU, Tetsuya ...2013 Volume 59 Issue 3 Pages 115-121
Published: May 20, 2013
Released on J-STAGE: June 01, 2014
JOURNAL FREE ACCESSDiphenidol and betahistine are anti-vertigo medications used for the treatment of vertiginous disorders. In the present study, we compared the therapeutic effects of diphenidol and betahistine on the handicap in daily life due to vertigo in patients with acute vertigo. The administration of diphenidol for four weeks significantly decreased the scores for factor 1: handicap in social activities, factor 2: handicap in head movements, factor 3: handicap in body movements, factor 4: handicap in emotion, factor 5: handicap in human interactions and factor 6: handicap due to discomfort. Because diphenidol has both anti-vertigo and anti-emetic actions, these findings suggested that its administration for four weeks recovered the functional handicap associated with factors 2 and 3 and the discomfort handicap of factor 6, resulting in recovery of the social handicap in factors 1 and 5 and emotional handicap (factor 4) in patients with vertigo. On the other hand, the administration of betahistine for four weeks only significantly decreased the scores of factors 1 and 5. This finding suggested that long-term administration of betahistine may be necessary to recover the other factors associated with handicap in patients with vertigo, because betahistine is reported to gradually accelerate the process of vestibular compensation after the development of vestibular asymmetry.View full abstractDownload PDF (816K) -
Kazuhiko KUBO, Masanobu SATO, Shizuo KOMUNE2013 Volume 59 Issue 3 Pages 122-127
Published: May 20, 2013
Released on J-STAGE: June 01, 2014
JOURNAL FREE ACCESSIsosorbide is one of drugs used for the treatment of patients with Meniere's disease, but there is often poor compliance due to its bitter taste. We recruited healthy volunteers to test whether isosorbide could be made more palatable by adding it to a beverage. The subjects frequently complained of a bitter taste when they took isosorbide alone. They documented that there was a significantly improved taste when they took isosorbide by adding it to orange juice, coca-cola oran ion-tonic beverage. However, they tended to document that there was an even worse taste when they took isosorbide after adding it to green tea. These results indicate that adding isosorbide to orange juice, coca-cola or an ion-tonic beverage may improve drug compliance.View full abstractDownload PDF (707K) -
Michio TOMIYAMA2013 Volume 59 Issue 3 Pages 128-133
Published: May 20, 2013
Released on J-STAGE: June 01, 2014
JOURNAL FREE ACCESSWe encountered two cases of Type A influenza infection complicated by a bacterial infection of the epipharynx. Both cases tested positive forType A influenza based on a rapid influenza diagnosis, and although an endoscopic examination revealed no inflammatory findings in the oropharynx, both reddening and pus were observed in the epipharynx. Blood tests showed an increased white blood cell count (neutrophil dominant), and the results of a bacterial test of the epipharynx were 5 + for Haemophilus parainfluenzae, and therefore the cases were diagnosed to have Type A influenza infection complicated by a bacterial infection of the epipharynx. In both cases, the oropharyngeal findings were normal, and the pharyngeal pain was not severe, and therefore these cases could have been sufficiently treated by solely administering an appropriate anti-influenza drug and conservatively monitoring the case in routine clinical practice. Even when the subjective and systemic findings are compatible with influenza, the presence of pharyngeal pain suggests that not only rapid testing for influenza, but also an endoscopic examination should be performed, while bearing in mind the possibility of a coexisting bacterial infection of the epipharynx.View full abstractDownload PDF (1828K) -
Michio TOMIYAMA2013 Volume 59 Issue 3 Pages 134-140
Published: May 20, 2013
Released on J-STAGE: June 01, 2014
JOURNAL FREE ACCESSWe recently encountered three cases of viral infection with inflammatory findings in the epipharynx. One of the patients was infected with the influenza virus, while another had an adenovirus infection, and the third had infectious mononucleosis. The patient with a Type A influenza virus infection demonstrated reddening of the epipharynx, while the patients with the adenovirus infection and infectious mononucleosis showed the presence of white moss on the epipharynx. It is difficult to differentiate between viral epipharyngitis and bacterial epipharyngitis based on the endoscopic findings alone, and therefore it is necessary to carefully differentiate between these conditions with the use of rapid diagnostic tests for viral infections, combined with various blood tests.View full abstractDownload PDF (6686K)
Clinical Note
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[in Japanese]2013 Volume 59 Issue 3 Pages 142-145
Published: May 20, 2013
Released on J-STAGE: June 01, 2014
JOURNAL FREE ACCESSDownload PDF (857K)
Erratum
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2013 Volume 59 Issue 3 Pages e1-e2
Published: May 20, 2013
Released on J-STAGE: June 01, 2014
JOURNAL FREE ACCESSDownload PDF (567K)
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