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Volume 42, Issue 4Supplement1
Displaying 1-8 of 8 articles from this issue
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[in Japanese], [in Japanese], [in Japanese], [in Japanese]1996 Volume 42 Issue 4Supplement1 Pages 475-479
Published: July 20, 1996
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESS -
Bunsuke SATAKE1996 Volume 42 Issue 4Supplement1 Pages 480-485
Published: July 20, 1996
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSA comparative study of two combined chemotherapy regimens for advanced head and neck cancer was performed by 17 cancer hospitals in Japan. The first study was a comparison of combined chemotherapy with CDDP, Peplomycin, MTX (PPM) and combined chemotherapy with CDDP, Bleomycin, MTX (PBM). The effective rate of the PPM was 51.5% and the effective rate of the PBM was 43.9%. But the survival rate of PR cases, NC cases and PD cases was alomost the same exept for the CR cases. The second study was a comparison of combined chemotherapy with CDDP, Peplomycin, MTX (PPM) and combined chemotherapy with CDDP, Peplomycin (PP). The effective rate of the PPM was 60.9% and the effective rate of the PP was 23.1%. The survival rate of PR, NC, PD was also almost the same. These results mean that the effect of the chemotherapy does not relate to the survival rate except in the CR cases. The relationship of the oral administraion of anti-cancer medicine as 5FU or UFT after the radical treatment and survival rate of Stage III and IV head and neck cancer in Gunma Cancer Center was investigated. The survival rate of the adjuvant chemotherapy group was higher than the non without adjuvant chemotherapy group, especially in maxillary cancer. But in the case of hypo-pharyngeal cancer the results were the same. This result suggests that systemic adjuvant chemotherapy is indicated for hypo-pharyngeal cancer.View full abstractDownload PDF (9111K) -
[in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...1996 Volume 42 Issue 4Supplement1 Pages 486-497
Published: July 20, 1996
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESS -
Kunitoshi YOSHINO, Takeo SATO, Takashi FUJII, Ken-ichi INAKAMI, Michik ...1996 Volume 42 Issue 4Supplement1 Pages 498-504
Published: July 20, 1996
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSIn an attempt to evaluate the late complications and problems of radiation therapy for laryngeal cancer, the clinical records of 175 patients, who received therapeutic irradiation between 1979 and 1984 at Osaka Medical Center for Cancer and Cardiovascular Diseases, were reviewed. There were 152 cases of glottic carcionoma and 23 of supraglottic carcinoma. The distribution of T-stage (UICC, 1987) was as follows; 150 in T1, 19 in T2, two in T3 and four in T4. The total dose was 60-70 Gy in 30-35 fractions with 4 MV linear accelerator using a opposed two-field technique. The T1 glottic lesions were treated with small portals (5×5cm2 or 6×6cm2). Development of cancer within the prior field of irradiation was observed in six patients (3.4%); three on the same site with the initial region after five years or more from initial radiotherapy (late recurrence) and three (1.7%) on the different site (one in the larynx and two in the hypopharynx).Chondritis, chondronecrosis and pharyngeal stenosis were not observed. Only one patient had persisting arytenoid edema for more than six months, while there was no severe edema requiring tracheotomy. The other minor late complications consisted of impaired cord mobility in four patients and polypoid lesion of the vocal cord in seven. These results suggest that precise radiation therapy for laryngeal cancer is a secure and excellent treatment modality.View full abstractDownload PDF (14508K) -
Masahisa SAIKAWA1996 Volume 42 Issue 4Supplement1 Pages 505-514
Published: July 20, 1996
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSDuring the 23 years between 1962 and 1984, 343 cases received radiotherapy for previously untreated squamous cell carcinoma of the tongue in the National Cancer Center Hospital. The three-year local control rate was 82.0% and the five-year survival rate was 64.7%. Of 218 patients followed up more than five years, 27 cases (12.4%) developed second malignancies in the oral cavity and/or oropharynx more than five years after the first radiation therapy. The second malignancies were most frequent from five to ten years after the initial treatment and on the same side of the tongue as the first radiotherapy. Radiation damage was observed in 28 cases (47%) out of 60 cases who had received interstitial radiotherapy between 1978 and 1984 and had been followed up more than five years. Five cases with sever ulcer and/or osteoradionecrosis required surgery.View full abstractDownload PDF (19932K) -
[in Japanese]1996 Volume 42 Issue 4Supplement1 Pages 515-518
Published: July 20, 1996
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESS -
[in Japanese]1996 Volume 42 Issue 4Supplement1 Pages 519-524
Published: July 20, 1996
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESS -
Yasuhisa HASEGAWA, Hidehiro MATSUURA, Bin NAKAYAMA, Yasushi FUJIMOTO, ...1996 Volume 42 Issue 4Supplement1 Pages 525-530
Published: July 20, 1996
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSWe examined recurrences and their forms in early pharyngeal cancers treated by irradiation and the obtained treatment policy in the future. From 1978 to 1994 sixty nine previously untreated patients with squamous cell carcinomas of the pharynx were examined. Their primary sites were the nasopharynx in 28, the oropharynx in 35 and the hypopharynx in 6. As a rule, T1 and T2 were assumed to be an early stage. In the early nasopharyngeal cancers, we observed many distant metastasis recurrences, similar to the number of recurrences in advanced cases. In the oropharyngeal cancers, a lot of local recurrences were detected in the anterior pillar and the soft palate as tumor subsite, in the invasive and ulcerative tumor as macroscopic tumor type, and in the well-differentiated tumor as histological differentiation. In the hypopharyngeal cancers, early pyriform cancers seemed to require an application of the radiotherapy. In the cancers of nasopharynx and oropharynx, the improvement is expected because of the potentiation by the use of the radiotherapy together with chemotherapy.View full abstractDownload PDF (13148K)
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