1, 402 cases of bronchoscopy and esophagoscopy were performed during seven years under local anesthesia using 1 per cent solution of T-caine*, pantocaine (2 per cent) and xylocaine (2 per cent).
Among the seven cases, in which shock reaction was observed, T-caine was used in six cases and in one case pantocaine was used, though no error in either dosis or premedication were noticed.
Bronchoscopy was succesfully performed repeatedly 18 times in one case of tuberculous bronchitis. However, shock had occured in the subsequent bronchoscopy trial, though the same anesthetica was used. Similar case was encountered in case of benign bronchial tumour, in which bronchoscopy was performed 8 times and shock had occurred in the subsequent trial. In the other case esophagoscopy was performed two times by another docter before during the past two months.
During the third esophagoscopy death had occurred because of the shock, though only 2 ml of T-caine was used.
In view of the studies on the cases in which shock was encountered, the following points should be kept in mind.
1. Perhaps patient's constitution has some bearing on the occurrence of shock. However, other possible causes should also be emphasized.
2. Special care must be taken in case of hypotension. Premedication and relaxation before operation are also important. 3. Extraordinary care should be taken in patients who are accustomed to take cortisone or in patients who have possible suprenal disorders.
As a result of the studies presented in the present communication, following measures recommended.
1. Bronchoscopy should be performed as quickly as possible. Drug solution and secretions which remain in trachea and bronchi should be removed by suction so as to keep airway clear.
2. In case of serious convulsion, barbiturates are advisable. Special care should be taken for dosis in order to avoid respiratory depression.
3. Sufficient quantity of oxygen should be provided by means of intubation and resuscitator.
4. Vagopressor should be used against hypotension-such as intravenous and intracardiac injection of noradrenaline, neosynephrine, ephedrine ete.
5. Intravenous drip of glucose or saline solution with hydrocortisone or ACTH, cardiac stimulants, vitamines and blood transfusion will be helpful.
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