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Volume 43, Issue 1
Displaying 1-14 of 14 articles from this issue
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Mako KATO, Tatsuya INAMURA, Ayumi MATSUMOTO, Asako KISHIMOTO, Toshiro ...1997 Volume 43 Issue 1 Pages 1-4
Published: January 20, 1997
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSA dilatation of the parotid duct (Stenon's duct) is found in the sialodochitis or sialolithiasis. We herein report the case of a localized extreme dilatation of Stenon's duct. A 45-year-old woman presented with a chief complaint of swelling in her right cheek after eating, which then disappeared at rest. The duct orifice was very small, so it was difficult to perform sialography. The sialogram, however, revealed an extreme dialatation of Stenon's duct. No caliculi were observed. The stenosis of the duct orifice was considered to be one of the main causes of the symptoms, and we therefore enlarged the duct orifice orally. After the operation, the swelling in the cheek after eating no longer occurred. We thus called this case a cyst of Stenon's duct because it was similar to a cyst of the common bile duct.View full abstractDownload PDF (7839K) -
Asako KISHIMOTO1997 Volume 43 Issue 1 Pages 5-8
Published: January 20, 1997
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSFreeman-Sheldon syndrome, which is a very rare congenital malformation, is characterized by features of whistling face, ulnar deviation, and talipes equinovarus. Hypertelorism, epicanthus, hypoplastic nose, long philtrum and microstomia were all found on the face of the patient. Talipes equinovarus was also seen on the bilateral feet. In addition, wrist joint contractures and ulnar deviation were also observed on the patient's bilateral hands. Hypertelorism and epicanthus were all treated successfully by the Mustardé method and microstomia was repaired by Barsky's method. In the pathological investigation of the orbicularis oris muscle, the muscle bundle was also waved and partially replaced by collagen fibers.View full abstractDownload PDF (8401K) -
A study using 80 normal sobjectsMutsuko TSUCHIYA1997 Volume 43 Issue 1 Pages 9-18
Published: January 20, 1997
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSIt is well known that many patients with vertigo become vertiginous when an alteration of the body position occurs while either looking back or after standing up. Stabilometry conducted with those patients when standing still is thus not always successful in detecting abnormal symptoms. However, our clinical research has shown that such abnormalities can be easily detected when the patients are subjected to motion-stress, such as head-shaking or alterations of the body position. The effect of such motion-stress on the disturbance of the centroid in normal individuals has yet to be clarified. In this study, stabilometry was conducted on 80 normal subjects who were subjected to motion-stress in the manner mentioned above and the results of this test were then compared with the findings of a conventional test. Through this comparison no increase in the imbalance, as a result of the applied motion-stress, was observed for the X Distance (XD), Y Distance (YD), Length (LNG) and Envelope (ENV) Areas. However, a significant increase in the imbalance was found for the XD, LNG and ENV Areas in the subjects over 70 years of age. In addition, the standard deviation of the LNG and ENV Area and individual difference were observed to increase in line with the increase in the age of the subjects.View full abstractDownload PDF (19699K) -
Kouichi YASUDA1997 Volume 43 Issue 1 Pages 19-24
Published: January 20, 1997
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSPatients with Méniére's disease may occasionally display transient spells of rotary nystagmus on positional testing during the course of the disease. This condition, in which the patients demonstrate nystagmoid movement of the eyes, is appropriately termed benign paroxysmal positional nystagmus of Meniere's disease, and is distinct from benign paroxysmal positional vertigo which is generally accepted to be an independent otologic entity. We experienced 8 cases with such episodes of rotary nystagmus during the past 3years. In 7 of these 8 cases the nystagmus persisted in spite of being treated. It is interesting to note, however, that in all of these 7 cases a marked tendency toward depression was observed, while the patients, when administered with antidepressants at appropriate dosage levels, ceased to develop nystagmus. Based on this finding, the patients' depressive state appears to be the primary cause of the persistant nystagmoid movement of their eyeballs.View full abstractDownload PDF (9037K) -
Tsutomu KURODA, Masaaki KASHIWAMURA, Yasushi FURUTA, Yukio INUYAMA1997 Volume 43 Issue 1 Pages 25-29
Published: January 20, 1997
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSWe recently experienced 2 cases of metastatic cancer of unknown primary lesions. The primary lesion was identified in the lungs after surgical operation. Before the initial treatment no tumorous lesions were obverved except for cervical metastasis. Radical neck dissections were performed in both cases and the pathological diagnosis was well differentiated squamous cell carcinoma and small cell carcinoma. Although metastases to the upper cervical nodes from the subclavicular region is rare, such a histology sometimes suggests a primary lesion. The patients whose primary lesions were not found despite multiple examinations of the head and neck may thus include primary lung lesions. Therefore the lung must be carefully examinad whenever a physical examination suggests the existence of primary lesions.View full abstractDownload PDF (10593K) -
Jun KITA, Hiroshi IWAI, Shinya TOYOKUNI, Masahiro YANAGIDA, Eiko KAWAS ...1997 Volume 43 Issue 1 Pages 30-33
Published: January 20, 1997
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSA rare case of low grade malignant myoepithelioma arising from the hard palate is reported. The CT findings indicated a defect of the hard palate due to the tumor. Surgery combined with postoperative irradiation therapy was performed. A histopathological examination indicated that the tumor originated in the myoepithelial cells, invaded the hard palate, and also showed cellular atypia with rare mitoses. Malignant myoepithelioma clinically shows a low sensitivity to both radiation therapy and chemotherapy. Surgery should thus be the first choice of treatment.View full abstractDownload PDF (8502K) -
Hiroyuki MAEDA, Shizuo KOJYA, Tetsuo ITOKAZU, Yukio NAKAMURA, Tatsuhit ...1997 Volume 43 Issue 1 Pages 34-37
Published: January 20, 1997
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSEwing's sarcomas are considered to be malignant bone tumors which usually arise in the medullary tissue of the long bone or pelvis. In the head and neck region, primary Ewing's sarcoma is very rare. In this report, a rare case of primary Ewing's sarcoma, which arose in the soft tissue of the right nasal cavity and then invaded the cranial base is presented. The patient was treated by chemotherapy followed by radiotherapy. The tumor in the nasal cavity was obscured after radiation, however, the tumor recurred in the madullary tissue of the bone, which thus led to DIC. The chemo-radio therapy reginen proved to be effective but not sufficient.View full abstractDownload PDF (8548K) -
Setsuko TAKEDA, Taizo TAKEDA, Haruo SAITO1997 Volume 43 Issue 1 Pages 38-47
Published: January 20, 1997
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSWe previously reported that an interruption of the petrosal branch produced delayed facial palsy in guinea pigs. Its time-course resembled the natural course of idiopathic facial palsy in humans. In the present study, we investigated the chronological course of the histological changes in the facial nerve after such an interruption. The results were as follows: 1) The ratios of the facial nerve to the facial canal (Fn/Fc ratios) differed between the two types of tissue processing, paraffine-celloidine embedding and epoxy resin embedding. The former were thought to represent the edema of the facial nerve better than the latter. 2) The Fn/Fc ratios increased from the 3rd to the 7th day after the interruption. Thereafter, the Fn/Fc ratio decreased until reaching a normal value on the 28th day after the interruption. 3) Myelin damage was more rarely observed in animals with slight and moderate palsy. In contrast, myelin damage was markedly observed in animals with facial palsy.View full abstractDownload PDF (20552K) -
Kayoko HIRATA, Mamoru TSUKUDA, Shigeru FURUKAWA, Hidehiro KOUNO, Satos ...1997 Volume 43 Issue 1 Pages 48-56
Published: January 20, 1997
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSForty-four patients with chronic sinusitis were treated with low-dose levofloxacin (100mg/day) for 8 weeks. The overall effective rate including both excellent and good clinical responses in subjective symptoms was 29% for rhinorrhea, 41% for postnasal drip, 42% for nasal obstruction, 52% for headache and 53% for hyposmia. Each effective rate of objective signs was 30% for nasal mucosal hyperemia, 42% for nasal mucosal edema, 55% for the volume of rhinorrhea, 61% for the quality of rhinorrhea and 70% for postnasal drip. These subjective symptoms, the objective signs and the X-ray findings for paranasal sinus all significantly improved after the treatment (P<0.001). No significant side effects were found during this treatment course. The clinical efficacy at 8-weeks was better than that at 4 weeks and no relationship was observed between the bacterial effects and the clinical effects. Therefore, the effective mechanism of this therapy was not considered to be associated with its antibacterial activity, but instead with some unknown mechanism, such an immunological enhancement.View full abstractDownload PDF (14485K) -
III. Nasal Allergy against orchardgrass and ragweedAkira MIYOSHI, Lei CHENG, Ming YIN, Zhibin CHEN, Haibo SHI, Qichang XU ...1997 Volume 43 Issue 1 Pages 57-61
Published: January 20, 1997
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSAn epidemiological study on nasal allergy was conducted on freshman and senior students at Nanjing Medical University, China. In this study, we examined the presence of nasal allergy against orchardgrass and ragweed, in addition to the other common allergens (house dust, mites snd cedar pollen) examined in previous reports. No case of nasal allergy against orchardgrass or ragweed was found, and only one case, who was positive against mites, was diagnosed to have a nasal allergy. In Japan, only a small number of nasal allergy cases were observed before the seventies, however, the number has dramatically increased since then. It is thus speculated that changes in external factors somehow contribute to this increase. Although we cannot make any sweeping statements about China, which has a vast land area, and where variations among different localities are quite large, the present social development status seems to be closely similar to that in Japan before the seventies. Therefore, if China continues to achieve economic affluency similar to that achieved by Japan in the seventies, then nasal allergies might also increase in China the way they have in Japan.View full abstractDownload PDF (8264K) -
Comparison of the data for 1989, 1992 and 1995Takeyuki SAMBE, Emiko SUZUKI, Kei TOKUMARU, Akira MIYOSHI, Ni FENG, Le ...1997 Volume 43 Issue 1 Pages 62-65
Published: January 20, 1997
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSEvery three years, a scratch test is conducted at an annual collective health check at a school in Shiraoi-cho, Hokkaido, on first and fourth graders in elementary school and on first-year junior high school students. A comparison of the scratch test results for 1989, 1992 and 1995 for the same groups of pupils showed that the positive rate increased with the growth of the pupils. The obserbed increase in the positive rate according to the pupils' growth is speculated to be correlated with the duration of exposure to allergens.View full abstractDownload PDF (7819K) -
Masashi IMANAKA, Yuzo YAMAMOTO, Atsushi SAKAKURA, Noriya KAKITSUBA, Ma ...1997 Volume 43 Issue 1 Pages 66-70
Published: January 20, 1997
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSThe following two studies were carried out to evaluate the clinical usefulness of sparfloxacin (SPFX). 1) SPFX was evaluated for its penetration into nasal polyp tissue in six patients with a nasal polyp. SPFX was administered orally at a single dose of 200mg after breakfast once a day for three days. Tissue specimens of the nasal polyps were then removed and venous blood samples were collected simultaneously four hours after administration to examine the concentration of SPFX in them. The tissue concentration of the nasal polyps was 0.76±0.43μg/g and the serum concentration was 1.01±0.50μg/ml. The tissue/serum ratio, which means the tissue penetration ratio, was 0.80±0.32, which indicates that the penetration of SPFX into the nasal polyps was good. 2) SPFX was evaluated for its effectiveness, safety and usefulness in eight patients with paranasal sinusitis. SPFX was administered orally at a single dose of 200mg after breakfast once a day for seven days. Its overall usefulness was 75% in acute paranasal sinusitis and 25% in acute exacerbated chronic cases. No side effects were noted. These results thus indicate that SPFX is useful in the treatment of paranasal sinusitis by only a single administration per day, except for highly incurable cases.View full abstractDownload PDF (10047K) -
Hideo MICHISHITA, Minoru IIDA, Hideyuki IWASA, Junko SUGIYAMA1997 Volume 43 Issue 1 Pages 71-81
Published: January 20, 1997
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSPemirolast potassium (Aiegysai®) was administered to 58 patients demonstrating an allergy to cedar pollen in 1995, at about 3.6 weeks before the onset of the cedar pollen season, to see if preseasonal administration would prevent symptoms. Efficacy was evaluated in 46 patients, including 35 patients who received preseasonal treatment and 11 patients who only received therapeutic treatment. 1. The percentage of patients with slight to severe symptoms was significantly higher in the preseasonal treatment group early in the cedar pollen season. 2. As for the severity of symptoms, early in the cedar pollen season the scores were significantly lower in the preseasonal treatment group than in the therapeutic treatment group. In the middle of the cedar pollen season the nasal congestion scores were also significantly lower in the preseasonal treatment group. 3. Adverse reactions occurred in 2 patients (2/44; 4.5%) given preseasonal treatment and in 1 given therapeutic treatment (1/14; 7.1%) All adverse reactions were resolved after either the termination or temporary discontinuation of the medication. These findings indicate that although the symptoms of cedar pollen allergy can not be prevented, they can at least be suppressed by administering Alegysal® before the onset of the cedar pollen season.View full abstractDownload PDF (16257K) -
Kouichi MATSUDA, Kenichiro NOGAMI, Osamu NISHIHIRA, Shoji KUDO, Shigeh ...1997 Volume 43 Issue 1 Pages 82-94
Published: January 20, 1997
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSEpinastine Hydrochloride was administered to one group of patients suffering from cedar pollenosis before the start of the cedar pollen season and to another group after the onset of the cedar pollen season and then the clinical effectiveness of the treatment between the two groups was evaluated. As a result, the following was observed:
1. Sneezing, nasal secretion, nasal obstruction, the severity of symptoms and eye itching were all milder in the group treated before the onset of the pollen season than in the group treated after the season had already begun.
2. However, the overall symptoms were more severe at the start of the pollen season in the group treated before the season began.
3. Lacrimination was milder throughout the observation period in the group treated before the start of the season than in the group treated after the season had already begun.
4. Regarding side effects, a transient increase in the total bilirubin was noted in 1 of 50 patients (2%) however, this resolved as the treatment was continued.
5. The treatment was thus found to be useful in 12 of the 18 patients (66.7%) treated before the beginning of the season and in 6 of the 8 patients treated during the season.
These results therefore suggest that Epinastine Hydrochioride helps to alleviate the symptoms of cedar pollenosis when it is administered before the start of the pollen season.View full abstractDownload PDF (19045K)
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