In the operative treatment of otitis media chronica up to this time, a disappearance of inflammation has been the main subject, but a disappearance of auditory acuity has hardly been taken into consideration. We tried, therefore, a literal observation inferring the otitis media sound conduction theory about the auditory acuity in tympanoplastic, the radical operation of otitis media and the conservative radical operation. The auditory tympanoplastic herementioned remains in ideal form, and it is clear that the ideal and the practical do not always meet, and even if the auditory acuity made temporary progress, it would not continue its durability. We believe from this viewpoint that more research and improvement in operation should be left to the future oto-rhinoeogists.

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This is a report on the early exeresis of a left acoustic nerve tumor from a forty-year-old housewife. In this case it was noticeable that all subjective symptoms had well disappeared after the operation and the prognosis was very good. From this the necessity of early diagnosis is emphasized. The symptoms which made this diagnosis possible were labyrinthine deafness in pure ton and speech hearing on both side, little functioning of the left vestibule, disappearance of the left corneal reflex, left facial paralysis, etc. Above all, the temporary threshold shift is to be noticed with its easiness of application and the progress both pre- and post-operation constantly showing normal recovery. The clinical diagnosis was also proved by the result of the operation in which the doveegg-sized tumor consisting of parenchyma and cystoma (50-50) was found on the left microencephalon part. The extracted sample was a typical neurinoma.

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It has been reported that streptomycin used in 154 cases has been investigated by audiogram and the following results were obtained.
1. The hearing impairments due to streptomycin were at the beginning almost a loss of high tone.
At that time the tendency for growing worse was severe in the gradual form of high tone loss and slight in the dip form of it.
2. The gradual forms were seen more in the dosage of dihyerostreptomycin and the dip forms were seen more in cases of compoundstreptomycin than the other streptomycin.
3. The severely impaired cases were found in the cases in which dihydrostreptomycin or streptomycin were injected every day, but were not found in the cases in which the compoundstreptomycin was injected twice a week.
4. The injection of high unit Vitamin B₁ after the use of streptomycin could prevent hearing impairments in some cases.

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Authors experienced this unusual case in which streptomycin deafness occurred in four members of one family.
Case I. The second daughter, aged twenty-one and unmarried, had tinnitus one month after taking 20g. of Dihydrostreptomycin, and a hearing disturbance about three months after this. It became absolutely impossible for her to join daily conversation for about one year thereafter. Case II. Tinnitus occurred in the first daughter, twenty-eight years old and married, two months after taking 18g. of Dihydrostreptomycin ; she had a hearing disturbance three months after. It became more difficult for her to participate in daily conversation for about one year after.
Case III. The mother, aged fifty-four, developed tinnitus in the first day after taking an unknown quantity of Dihydrostreptomycin for three days. She developed a slight hearing disturbance two months after and it continues up to now.
Case IV. Tinnitus began in the second son, twenty-four years old, two months after taking 30g. of Dihydrostreptomycin, and developed a hearing difficulty four months after. He is now receiving treatment and has a serious high tone deafness.
It is supposed that the members of this family have a hereditary weakness in their nerve construction from the fact that all of them had simlar doses of Dihydrostreptomycin, similar times of appearance of hearing difficulty, and much the same progress of disease.

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Giving Chlorpromazine pills to forty-four patients with tinnitus, affects were recognized in twenty-three cases (52.2%). Classifying them by their diseases, it was very effective on catarrhal otitis media and Ménière's disease, but it did not affect injury on the head, tinnitus from sound, and acoustic trauma. The period of administering Chlorpromazine must be long and in most cases the time fo r curing tinnitus is fourteen to thirty days.
The effect of Chlorpromazine is supppsed to come from the palliation of the twitch of blood vessels by intercepting the symoathetic nerve system and vasodilation.

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In thirty persons with Ménière's disease, spontaneous nystagmus, postional nystagmus, the caloric test and dii ectional prepondrance resulted in the fact that Ménière's disease mostly seemed to be a disease of the peripheral labyrinth.
The cases showing the directional prepondrance were 33 per cent and those of canal paresis were 50 per cent, while the normal ones were 17 per cent. Accordingly, this directional prepondrance would be due to a peripheral origin.

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A twenty-year-old female appeared with an abscess in the nasal septum on the thirteenth day of disease, and had been treated by an intern with the application of sulfa-preparation, aureomycin, streptomycin, and others, under the doubt of tuberculous meningitis because of high fever, neck stiffness and the finding of liquor.
This fact made the cause of leptomeningitis unknown and also prolonged the rhinological investigation under the obscure appearance of the septal abscess.
Staphylococci and diplococci were found in the bloody pus from the septal abscess; accordingly achromycin of 12gm. in total dose was applied after the incision and the removal of the sequester.
The patient has recovered but has a slight saddle-nose; however, the anosmia observed in the course of this disease was almost cured through the administration of 10mg. of “alinamin” daily for one month.

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A clinical report is made on a case of a 75-year-old woman who had a nasal stone in her left nasal cavity for about fifteen years. The stone was 2.8g. in weight and 3.5×1.4×0.9 in size.

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This is the report of the clinical progress and the results of autopsy on a thirty-six-year-old male who finally died of general weakness after a radical operation on both sides of the sinusitis, which was followed by progressive gangrene of the nasal fossa and facies ossea with 39-40 degrees C. temperature.
The result of this autopsy showed a granulomatous change in the artery system and its surrounding parts of the general internal organs, and a socalled form of periartritis nodosa was seen. This structure-form looked like the result seen in the alucus phenomenon, which is known as an allergic medical change. From this point, the allergic change seemed to be the cause of death. It was concluded that a certain group of cases which resemble this case might have an allergic element as their cause.

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The patient was a thirteen-year-old boy whose chief complaint was the swelling of the left cheek (zygomatic region). An operation performed for the condition of which he complained revealed the following facts.
1. There was an absence of the anterior and mesial walls of the maxillary sinus and the prescence of three large polyps filling up the sinus.
2. The. presence of a large antrochoanal polyp rising from the canopy of the sinus walls and extending into the nose and the posterior nasal cavity was found.
3. This was probably an instance of one type of the so-called mucocele sinus maxillae, produced by three large polyps in the maxillary sin ls with thc: effect of sinuitis cum dilatatione.

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The patient was a six-year old female. Her right cheek, having been hit hard four months before her entering the hospital, showed a slight swelling. Afterward since there was toothache the extraction of the first milk molar tooth of the right upper jaw was done. Later a fistula formed on the same spot. At the first examination a slight stiffness was recognized on the swellen part, but the Gerbel tuberosity was not seen in the right nasal cavity. The X-ray photograph showed a cystoma-like diaphaneity which occupied the right maxillary sinus. This cyst which was as big as a dove's egg, was wholly extracted by the Luc-Caldwell's method. In the cyst tooth was not found, but one normal tooth and two impacted tooth were extracted. The fistula was well-closed on the tenth day after the operation. The root cyst growing on the milk tooth is rare, but the results of the operation and also a X-ray photograph showed this to be a case of the cyst growing on the location of the extracted tooth.

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The Neurinom which was introduced and named by Jose Verocay in 1908 has three histological characteristics: 1) Palisadenstellung of the cell nucleus of a tumor, 2) the yellow coloration of the tumor fiber by the Van Gieson coloration, 3) typical ganglion cell, lacking the colloid cell, and embryologically said to be the ectodermal tumor which grows from Schwann's sheath.
This case, which was experienced on an outpatient of this department, was one in which the Neurinom appeared on the bottom of the oral cavity. Fortunately the whole process of this case was examined by literal observation as well as clinical observation as follows: age, sex, part of generis, symptoms, diagnosis, treatment, prognosis, etc. This case was at first diagnosed as cases up to this time, that is, to be a cuticular cyst on the bottom of the oral cavity, and only after its extraction was it found to be Nuerinom by histological research.

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This case is one of a skin disease in which phyma moved all over the skin of the whole body, which was infected by the patient's eating raw ophicephalus argus which had the parasite gnathostomiasis; the parasite drilled through the esophagus gastro-enteropathy, and the disease moved to the larynx causing a serious condition.
The thirty-eight-year-old patient had an oedema swelling from his lower jaw through the cheek down to the larynx a month after eating raw ophicephalus argus, and paralysis of the vocal cords, hoarseness, and shortness of breath followed. This serious condition was relieved the Neo-minophagen C intravenous injection and Tab. supatonin. But the same disease has occurred twice since then.

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We report on a case of a giant laryngeal leiomyoma, 5.0×4.8×4.0cm., which grew in aforty-nine-year-old man, and was extracted by laryngofissure, and treated by a deep X-ray therapy (total amount 5000r) after which it was clinically supposed to be almost cured.
A definite diagnosis was not even obtained by the exploration. of the section tissue, which was done six times since this case had come through a peculiar process. Finally, the tissue of the tumor which was extracted operatively proved the diagnosis that it was leiomyoma but from this result it was cautioned that it was dangerous to rely just on a tissue section in diagnosing the case of leiomyoma. This case of laryngeal leiomyoma is the second one reported in Japan since Orii's.

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This is a report on a case in which a one inch U-shaped nail continued to stay in the right bronchus for about a year, and it was found by author. In the first two operations a bronchoscope improved by Ono was used peroral tracheobronchoscopically. In the first operation only granulation was found but not the foreign body ; in the second operation however, the foreign body was caught by Robert's clamp under the biplane fluoroscopy. But, fearing danger in its blind handling, the operation was stopped because of bleeding. In the third operation the foreign body was recognized percervial tracheoscopically by the Killian's bronchoscope and it was taken out without any danger in spite of some bleeding.
After the operation more investigation was done on the following points: why there were no supjective symptoms for about a year, the problem of the advantage in the tracheobronchoscopy through a tracheastoma, the comparison of the Killian's bronchoscope and Ono's bronchoscope, and moreover, the reasons for failure and success in the operations.

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Ein 14 jähriges Mädchen mit einer sezernierenden Fistel an der unteren Par tie des linken. vorderen Kopfnickerrandes suchte unser Ambulatorium auf. Dass die Fistel war eine komplette Form wurde durch die Eingiessung der Methylenblaulosung von der Fistel leicht konstatiert, d. h. die Methylenblaulosung ergoss aus der Oberpolgegend der linken Gaumentonsille.
Es war gelungen fül.: den Verfasser, die Fistelgang vollständig zu exstirpieren ohne Schn_eidung des Fistelganges auf halbem Wege. Die Operation wurde von aussen und von der Mundhöhle aus ausgeführt. Zuerst löste man stumpf den Fistelgang möglicherweise nach oben ab unter dem ungefähr 7 cm langen Hautschnitt am vorderen Kopfnickerrand, und dann nach der linken Tonsillektomie der bläulich verfärbte Fistelgang am hinteren Wundbett wurde ähnlicher Weise stumpf nach unten abgelöst bis der ganze Fistelgang war freibeweglich geworden.(Autoreferat)

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A twenty-six-year-old female noticed a hard tumor on the left parotid gland two years ago. Access attack, dryness of mouth, paralysis of the face, etc. were not noticed. The result of the sialography showed the pressed figure of the left parotid gland.
As a result of the operation it was known that the tumor existed just undei the platysma and roughly adhered to the parotid gland, being enclosed by a smooth capsula. The extracted tumor weighted fifteen grams and was 2.7×3.5×3.5cm. in size.
The result of histopathological research showed that the structure was formed by a gathering of cells in spindle shape or cubic shape, and these cells were connected in a net-like cord, resembling an endothelioma. In these net-like cords, cartilaginous tissue, mucous tissue or their transitional tissue was recognized. Thus this was the mixed tumor of the parotid gland. The incised region was promptly healed without forming a salivary fistula.

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Fundamentals and clinical applications of the low and high polymerised PVP are outlined and some clinical cases of the authors' experience are presented.
Clinical applications of PVP such as plasms expander, antidote, hemostatic, and hydro-metabolism adjusting agent are covered, and also reported are such applications as an anti-allergic agent and applications to virus diseases that have not been referred to so far. As an antidote, its action against streptomycin toxication is referred to especially and as a hydro-metabolism adjusting agent, its clinical application to cases of Meniere's syndrome is covered. Also the actions of low and high polymerised PVP to the “Winterschlaf-Narkose” were reported. The low promoted an awakening from it, and contrariwise, the high had a depot-action on it.
Regarding the characteristics of PVP, the wide field of its application is stressed clinically as well as theoretically with the aid of examples.

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