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Volume 28, Issue 2
Displaying 1-14 of 14 articles from this issue
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Kaoru TOSAKA, Takeru ISHIKAWA1982 Volume 28 Issue 2 Pages 161-173
Published: March 20, 1982
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSFour cases of the lethal midline granuloma or malignant granuloma of the nose were treated by irradiation and chemotherapy, which are generally prescribed for malignant lymphomas.
Clinical, histological and laboratory examination indicated that they were the lethal midline granuloma and clearly differentiated from Wegener's granulomatosis or malignant lymphoma.
All of the cases exhibited primary remission. The four cases were observed up to 38, 22, 14, and 10 months since the beginning of the therapy, showing no local or general recurrence.View full abstractDownload PDF (2944K) -
A Study with Moderate or Moderately-Severe Sensorineural Hearing LossEiko HIROTA, Kazuoki KODERA, Sachiko SAGAWA1982 Volume 28 Issue 2 Pages 174-179
Published: March 20, 1982
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSEfficacies of the hearing aids with different frequency responses were studied in 16 cases of moderate or moderately-severe sensorineural hearing loss.
Cases with similar audiograms were divided into two groups based on their severity of speech intelligibility. Speech discrimination tests using hearing aids of various frequency responses revealed that low frequency amplification of the aids improved the discrimination scores in a group with good speech intelligibility. In the group with poor intelligibility, low frequency amplification did not affect their discrimination scores.
For better selection of a hearing aid, the type of audiogram as well as speech intelligibility should be taken into account.View full abstractDownload PDF (680K) -
Chiharu HIRABAYASHI, Kazuo KAWARADA, Takashi TSUCHIYA1982 Volume 28 Issue 2 Pages 180-183
Published: March 20, 1982
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSA case of sterno-costo-clavicular hyperostosis occurred in a patient with chronic tonsillitis is reported.
A 47-year-old man had suffered from habitual tonsillitis for about fifteen years. In January 1979, he suddenly complained of pain in the right sterno-costo-clavicular joint region. In January 1980, a swelling suddenly appeared in the metacarpophalangeal joint of the left hand in which X-rays revealed hyperostosis. Blood examination revealed leucocytosis and raised ESR.
Histological examination of the biopsied tissue showed nonspecific arthritis on the sterno-clavicular junction. In August 1980, a tonsillectomy was performed. The tonsills were small and histological findings were that of a simple chronic inflammation.
Tonsillectomy was effective for relieving subjective and objective clinical symptoms of the hyperostosis, suggesting the possibility of the tonsillitis being responsible for the hyperostosis.View full abstractDownload PDF (4917K) -
Takuo MAEYAMA, Yuichi KURONO, Noriko HASHIMOTO, Fumiko IIDA, Yasuichi ...1982 Volume 28 Issue 2 Pages 184-187
Published: March 20, 1982
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSA case of a 4 year old girl with lymphangioma of the tongue was treated by CO2 laser surgery under general anesthesia. The tumor was vaporized completely with little bleeding and no subsequent pain.
The course of healing was good and there was no recurrence of the tumor.View full abstractDownload PDF (4449K) -
Ryuji KIYOTA, Shigeru FURUTA, Makoto YAMAMOTO, Takuo NOBORI1982 Volume 28 Issue 2 Pages 188-195
Published: March 20, 1982
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSTwo cases of lateral cervical fistulas originating from the third or the fourth branchial pouch are reported. Case 1 was a 3-year-old girl with the complaints of salivary flow in the fistula of the neck in the left lateral side. This case was diagnosed by observation with a flexible fiberscope for the larynx during retrograde injection of an amount of milk through the external orifice of the fistula. Case 2 was a 44-year-old man who had complaints of a painless swelling in the left side of the neck, dysphagia and husky voice.
Fistulas of these cases were completely removed under general anesthesia. Histologically, the inner surface of the fistula in case 1 was lined by stratified columnar epithelium, and in case 2 it was lined by stratified squamous epithelium.
A review of Japanese literature of lateral cervical fistulae was done and is discussed briefly from the viewpoint of histogenesis.View full abstractDownload PDF (7309K) -
Toru TAKIMOTO, Kazuo MORISHITA, Yohji ISHIBASHI, Fumihiro KAMIDE, Mits ...1982 Volume 28 Issue 2 Pages 196-202
Published: March 20, 1982
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSAnti-nuclear antibodies (ANA) were studied by an immunofluorescent method in 55 patients with head and neck cancer, 10 with tonsillitis and in 16 healthy adults.
The following results were obtained.
1) ANA were found in the sera of about 50% of the patients with nasopharyngeal carcinoma (NPC).
2) High complement-fixing activity of ANA was found in patients with NPC.
3) Six immunofluorescent staining patterns of ANA were observed. One type of anticytoplasmic antibody was observed in patients with NPC.
4) Patients with NPC showed significant increases in serum IgA levels. No correlation was found between the levels of ANA and serum immunoglobulins.View full abstractDownload PDF (2642K) -
Part 1: Anti-EBV Antibody Titration in Patients with Tonsillar DiseasesToru TAKIMOTO, Kazuo MORISHITA, Shigeru ISHIKAWA, Takashi KOMORI, Mits ...1982 Volume 28 Issue 2 Pages 203-207
Published: March 20, 1982
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSUsing an indirect immunofluorescent method, anti-EBV (VCA-IgG, IgM, IgA) antibody titers were measured. The samples were sera of 111 patients with tonsillitis (acute or chronic), 19 patients with adenoid hypertrophy and 4 patients with malignant lymphoma of the tonsils.
the results were In summary:
1) In the group of patients under 6 years old with tonsillitis, we observed a high titers of anti-VCA (IgG) antibody in the majority of cases.
2) In 12 patients, we observed the presence of anti-VCA (IgM) antibody and the results could indicate that these patients had tonsillitis by EBV.
3) There was not any relationship between titers of anti-VCA and ASO (or ASK).
4) Sixty percent of the patients with RA factor had the anti-VCA (IgM) antibody.
This could indicate a relationship between EBV infection and RA factor production.View full abstractDownload PDF (2111K) -
Shun WATANABE, Hiroshi OHKUBO, Kazuto NAGATA, Minoru HIRANO1982 Volume 28 Issue 2 Pages 208-213
Published: March 20, 1982
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSA 70 year old male with polypoidal tumor of the larynx was encountered by the authors. Histological findings revealed sarcoma-like areas with spindle cells and giant cells. The authors could not find the areas of apparent squamous cell carcinoma.
After various staining procedures, the histogenesis of the tumor was considered to be of epithelial origin and so-called carcinosarcoma seemed the most likely diagnosis.
The patient is in favorable condition today, 6 months after total laryngectomy.View full abstractDownload PDF (5716K) -
Toshio ITO1982 Volume 28 Issue 2 Pages 214-227
Published: March 20, 1982
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSThe three-dimensional arrangement of myofibril and mitochondria in five intrinsic laryngeal muscles, i. e. the cricothyroid, thyreoarytenoid, lateral cricoarytenoid, posterior cricoarytenoid and arytenoid muscles, were investigated by means of field emission scanning electron microscopy. The findings were as follows:
1. The basic structure of the myofibril, sarcoplasmic reticulum, transverse tubules and sarcolemma of the intrinsic laryngeal muscle were essentially the same as that of other skeletal muscles of mammals.
2. There are no significant differences in the structures of the five intrinsic laryngeal muscles.
3. Three types of mitochondria were observed underneath the sarcolemma: (1) Many mitochondria of round or rod-like shape,(2) A few elongated mitochondria, running parallel to the myofibrils,(3) Mitochondria with complex shapes e. g. spiral, tree-like and horsebean. The former two shapes were found frequently in the lateral portion of the thyreoarytenoid muscle and in the other four muscles, while the complex shape was found in the medial portion of the thyreoarytenoid muscle.
4. Three types of mitochondria were found between myofibrils: (1) Mitochondria of round or rod-like shape,(2) Elongated mitochondria, running parallel to the myofibrils, and (3) Mitochondira running perpendicular to myofibrils with branches of different shapes. The former two were found frequently in the lateral portion of the thyreoarytenoid muscle and in the other four muscles, while the latter was found in the medial portion of the thyreoarytenoid muscle.View full abstractDownload PDF (18893K) -
Kazuo KAWARADA, Chiharu HIRABAYASHI1982 Volume 28 Issue 2 Pages 228-231
Published: March 20, 1982
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSInterferon has been used for cancer of the head and neck because of its possible antitumor actions. In most cases, however, it has been systemically administered, and high and repeated doses are necessary.
The authors treated 5 cases of laryngeal carcinoma (T1N0M0 or T2N0M0) with 50,000 units of interferon, and observed improvement in some cases.
Since most of the cases had been concomitantly under radiotherapy, the evaluation of the effect of interferon is difficult, but one case where radiotherapy was ineffective, the tumor disappeared after administration of interferon.
The authors believe the improvement is the result of the direct action of interferon and assert that the therapy is a useful measure.View full abstractDownload PDF (3731K) -
Shigeru FURUTA, Katsunori FUKUDA, Hirofumi MATSUYAMA, Yuichi KURONO, K ...1982 Volume 28 Issue 2 Pages 232-237
Published: March 20, 1982
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSInvestigations of a new antibiotic, fosfomycin, were conducted. Concentrations in blood and tissues were studied 1 and 2 hours after administration of either capsule or dry syrup fosfomycin.
Two hours after administration of 2g of the dry syrup, the maximum concentration in blood was 8.31μg/ml, 4.51μg/g in palatine tonsil, 3.92μg in the mucous membrane of the maxillary sinus, 3.18μg/ml in maxillary exudate, 5.26μg/g in nasal polyp, 2.72μ/g in inferior turbinates, and 1.94μg/g in the nasal tumor tissue. No measurable concentration was found in exudate of maxillary cyst.
One hour after administration of 1g of syrup, the maximum blood concentration was 5.57μg/ml.
Two hours after administration of a 2g capsule, the concentration was 7.05μg/ml.View full abstractDownload PDF (679K) -
Yoshimi HARA, Minoru IDE, Tomoyuki NAGAI, Tamotsu MORIMITSU, Masami SH ...1982 Volume 28 Issue 2 Pages 238-244
Published: March 20, 1982
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSBacteriological investigation of the aural discharge in 144 cases of chronic suppurative otitis media from patients who visited our clinic from July 1980 to June 1981 was performed.
Ten ears were treated with KW-1070 (Fortimicin) and its effect was clinically evaluated.
The following conclusions were obtained.
1. Two hundred and twelve cultures were isolated from the 144 specimens. There were gram-positive cocci (51.9%), gram-positive bacilli (11.8%), and gram-negative bacilli (35.4%).
2. KW-1070 was administered to 8 cases (10 ears) with severe chronic otitis media. The clinical efficacy of KW-1070, as measured by diminished ear discharge, was 50%.
3. Bacteriologically, 12 of 20 different species of bacteria disappeared after treatment with KW-1070, however, 8 organisms were still cultured. The bacteriological efficiency of KW-1070, thus is 60%.
4. KW-1070 was significantly effective in one case which showed no sensitivity to AMK.
5. No serious side effects were observed, including hepatic, renal or auditory complication, except one case which showed a small and transient increase in GOT and GPT.View full abstractDownload PDF (750K) -
Satoshi FUKUDA, Yoshihiko TERAYAMA1982 Volume 28 Issue 2 Pages 245-253
Published: March 20, 1982
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSRecurrent aphthous stomatitis (RAS) is one of the common diseases affecting oral mucosa, but its aetiology has not yet been firmly established and its treatment has been unsatisfactory.
Recent immunologic investigations of RAS have focused attention on a possible immunopathogenesis. In this report, 23 patients with RAS were treated with Levamisole, an immunomodulatory agent. Each patient received three tablets a day (150mg) on three consecutive days every fortnight over one month.
The results of this pilot study were as follows.
1) Seventeen of 23 patients (70%) showed beneficial responses. Observed were a lengthening of the time between episodes; a shortening of the duration of the episodes; diminished pain, smartness and local heat; and a decreased number and size of aphthae.
2) Levamisole appeared to have a definite enhancing effect on the cellular immunity as measured by delayed type hypersensitivity to Candida, SK/SD, PPD, Mumps, PHA-P.
3) Several side effects (nausea, headache, granulocytopenia, etc.) were observed during Levamisole therapy, but severe manifestations were not observed. We conclude that Levamisole, a immunomodulator, is effective in treatment of RAS.View full abstractDownload PDF (1098K) -
1982 Volume 28 Issue 2 Pages 255-277
Published: March 20, 1982
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSDownload PDF (3539K)
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