A retrospective review was performed on 27 patients with primary hyperparathyroidism who were initially treated at our hospital between 2009 and 2012. The 27 patients ( 4 males, 23 females) ranged in age from 23 to 82 years. Histological examinations revealed 26 parathyroid adenomas and one parathyroid hyperplasia. Ultrasonography, computed tomography and
99mTc Sestamibi scintigraphy were useful modalities for accurately diagnosing the localization of the parathyroid gland tumors. When parathyroid gland tumors were not detectable by
99m Tc Sestamibi scintigraphy,
201TL-
99mTc subtraction scintigraphy was useful for diagnosing the localization. A resection of the enlarged gland was performed in 23 patients, a hemithyroidectomy and parathyroidectomy was performed in three patients and bilateral parathyroidectomy (two glands) was performed in one patient. The serum intact PTH concentration degreased in 16 patients during the operation. Twenty-six of the 27 patients were normocalcemic,however, the other patient had persistent hypercalcemia after the operation. This analysis suggests that measuring the serum intact PTH concentration during surgery is useful. Recurrent laryngeal nerve palsy was not observed in any of the patients, but the tetany and hypocalcemia were noted after the operation in six of the 27 patients.
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